{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T12:08:04Z","timestamp":1787832484925,"version":"build-2784847793"},"reference-count":15,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T00:00:00Z","timestamp":1758153600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T00:00:00Z","timestamp":1758153600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["S. Afr. j. radiol."],"abstract":"<jats:p>Background:\u00a0Intussusception is a common cause of paediatric bowel obstruction requiring urgent management to prevent ischaemia. Fluoroscopy-guided air enema reduction (FGAR) is the standard non-surgical treatment for uncomplicated cases.Objectives:\u00a0To identify factors associated with FGAR outcomes in paediatric intussusception.Method:\u00a0A retrospective analytical study was conducted at Universitas Academic Hospital, Bloemfontein, South Africa, including 110 patients with radiologically confirmed intussusception from November 2016 to December 2022. Data encompassed demographics, clinical presentation, laboratory results, and imaging findings.Results:\u00a0Among 110 cases (median age 7 months, symptom duration 2 days), 37 were primarily surgically managed, while 73 underwent FGAR attempts (31 successful, 42 unsuccessful, requiring surgery). Of the 79 surgical cases, 24 had manual reduction without resection. Unsuccessful FGAR was significantly associated with younger age (p\u00a0= 0.0249), dehydration (p\u00a0= 0.0299), ascites (p\u00a0= 0.0172), and increased outer wall intussusception diameter on ultrasound (p\u00a0= 0.0026).Conclusion:\u00a0In this South African cohort, unsuccessful FGAR was linked to younger age, dehydration, ascites, and larger intussusception size on ultrasound. Early recognition and routine ultrasound use are critical in resource-limited settings to enhance non-surgical outcomes and reduce surgical burden.Contribution:\u00a0This study identifies predictors of FGAR failure in a low-resource context, informing clinical decision-making and addressing a gap in the literature on intussusception management in low- and middle-income countries.<\/jats:p>","DOI":"10.4102\/sajr.v29i1.3155","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T07:52:07Z","timestamp":1757922727000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Risk factors associated with the outcomes of fluoroscopy guided pneumatic enema reductions of intussusceptions"],"prefix":"10.4102","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8472-2817","authenticated-orcid":false,"given":"Cornelia M.","family":"Kamffer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7787-7324","authenticated-orcid":false,"given":"Hilge","family":"Du Preez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5045-8728","authenticated-orcid":false,"given":"Jacques","family":"Janse van Rensburg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2025,9,18]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Younes A, Lee S, Lee JI, Seo JM, Jung SM. Factors associated with failure of pneumatic reduction in children with ileocolic intussusception. Children. 2021;8(2):136. https:\/\/doi.org\/10.3390\/children8020136","DOI":"10.3390\/children8020136"},{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Thanh Xuan N, Huu Son N, Huu Thien H. Treatment outcome of acute intussusception in children under two years of age: A prospective Cohort study. Cureus. 2020;12(4):e7729. https:\/\/doi.org\/10.7759\/cureus.7729","DOI":"10.7759\/cureus.7729"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Edwards EA, Pigg N, Courtier J, Zapala MA, MacKenzie JD, Phelps AS. Intussusception: Past, present and future. Pediatr Radiol. 2017;47:1101\u20131108. https:\/\/doi.org\/10.1007\/s00247-017-3878-x","DOI":"10.1007\/s00247-017-3878-x"},{"key":"ref3","unstructured":"Jain S, Haydel MJ. Child intussusception [updated 2023 Apr 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025."},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Hwa Kim P, Hwang J, Mang Yoon H, et al. Predictors of failed enema reduction in children with intussusception: A systematic review and meta-analysis. Eur Radiol. 2021;31:8081\u20138097. https:\/\/doi.org\/10.1007\/s00330-021-07935-5","DOI":"10.1007\/s00330-021-07935-5"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Liu ST, Tang XB, Li H, Chen D, Lei J, Bai YZ. Ultrasound-guided hydrostatic reduction versus fluoroscopy-guided air reduction for pediatric intussusception: A multi-center, prospective, cohort study. World J Emerg Surg. 2021;16(1):3. https:\/\/doi.org\/10.1186\/s13017-020-00346-9","DOI":"10.1186\/s13017-020-00346-9"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Akello VV, Cheung M, Kurigamba G, et al. Pediatric intussusception in Uganda: Differences in management and outcomes with high-income countries. J Pediatr Surg. 2020;55(3):530\u2013534. https:\/\/doi.org\/10.1016\/j.jpedsurg.2019.07.003","DOI":"10.1016\/j.jpedsurg.2019.07.003"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Pindyck T, Parashar U, Mwenda JM, et al. Risk factors associated with increased mortality from intussusception in African infants. J Pediatr Gastroenterol Nutr. 2020;70(1):20\u201324. https:\/\/doi.org\/10.1097\/MPG.0000000000002487","DOI":"10.1097\/MPG.0000000000002487"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Tran CD, Cheung C, Archambeau B, Dong F, Neeki MM. Pediatric intussusception following COVID-19 infection: A rare presentation. Cureus. 2022;14(3):e23488. https:\/\/doi.org\/10.7759\/cureus.23488","DOI":"10.7759\/cureus.23488"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Lee HJ. Plain abdominal radiography in infants and children. Korean J Pediatr Gastroenterol Nutr. 2011;14(2):130. https:\/\/doi.org\/10.5223\/kjpgn.2011.14.2.130","DOI":"10.5223\/kjpgn.2011.14.2.130"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Charles T, Penninga L, Reurings JC, Berry MCJ. Intussusception in children: A clinical review. Acta Chirurgica Belgica. 2015;115:327\u2013333. https:\/\/doi.org\/10.1080\/00015458.2015.11681124","DOI":"10.1080\/00015458.2015.11681124"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Kim JH. US features of transient small bowel intussusception in pediatric patients. Korean J Radiol. 2004;5(3):178\u2013184. https:\/\/doi.org\/10.3348\/kjr.2004.5.3.178","DOI":"10.3348\/kjr.2004.5.3.178"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Fakhry T, Fawzy AN, Mahdy AT. The efficacy of delayed, repeated reduction enema in management of intussusception. Ann Pediatr Surg. 2021;17(1):7. https:\/\/doi.org\/10.1186\/s43159-021-00072-0","DOI":"10.1186\/s43159-021-00072-0"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Sujka JA, Dalton B, Gonzalez K, et al. Emergency department discharge following successful radiologic reduction of ileocolic intussusception in children: A protocol based prospective observational study. J Pediatr Surg. 2019;54(8):1609\u20131612. https:\/\/doi.org\/10.1016\/j.jpedsurg.2018.08.042","DOI":"10.1016\/j.jpedsurg.2018.08.042"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Khorana J, Singhavejsakul J, Ukarapol N, Laohapensang M, Wakhanrittee J, Patumanond J. Enema reduction of intussusception: The success rate of hydrostatic and pneumatic reduction. Ther Clin Risk Manag. 2015;11:1837\u20131842. https:\/\/doi.org\/10.2147\/TCRM.S92169","DOI":"10.2147\/TCRM.S92169"}],"container-title":["South African Journal of Radiology"],"original-title":[],"link":[{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/3155\/3893","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/3155\/3894","content-type":"application\/epub+zip","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/3155\/3895","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/3155\/3896","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/viewFile\/3155\/3896","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T12:50:49Z","timestamp":1758891049000},"score":1,"resource":{"primary":{"URL":"https:\/\/sajr.org.za\/index.php\/sajr\/article\/view\/3155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,18]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12,10]]}},"URL":"https:\/\/doi.org\/10.4102\/sajr.v29i1.3155","relation":{},"ISSN":["2078-6778","1027-202X"],"issn-type":[{"value":"2078-6778","type":"electronic"},{"value":"1027-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9,18]]}}}