{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T17:47:47Z","timestamp":1785433667524,"version":"3.56.0"},"reference-count":43,"publisher":"AOSIS","issue":"1","license":[{"start":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:00:00Z","timestamp":1770854400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Conductive hearing loss (CHL) results from impaired mechanical transmission of sound through the external or middle ear and is commonly associated with conditions such as otosclerosis, cholesteatoma, ossicular discontinuity, congenital malformations and trauma. Less frequently, it may arise from vascular or neoplastic lesions. Imaging plays a central role in the evaluation of CHL, with high-resolution CT (HRCT) regarded as the gold standard for initial assessment because of its superior spatial resolution in detecting bony pathologies, including fenestral otosclerosis, ossicular chain defects, third-window lesions and trauma-related disruptions. MRI complements HRCT by providing excellent soft tissue contrast, facilitating the detection of postoperative cholesteatoma via non-echo-planar diffusion-weighted imaging and the characterisation of vascular tumours such as glomus tympanicum. CT angiography (CTA), while not routinely indicated, can be valuable for identifying vascular anomalies and aiding surgical planning in selected cases. Technical considerations, such as optimised scan parameters, strategies for radiation dose reduction in paediatric patients and the integration of multiple imaging modalities, are essential for accurate diagnosis and effective treatment planning. Collectively, HRCT, MRI and CTA provide a structured, evidence-based framework for the comprehensive evaluation and management of CHL.\nContribution:\u00a0This review synthesises current evidence on HRCT, MRI and CTA in the assessment of CHL, emphasising their complementary roles, protocol optimisation and multimodal integration to enhance diagnostic accuracy and surgical guidance in both paediatric and adult populations.<\/jats:p>","DOI":"10.4102\/sajr.v30i1.3278","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T09:30:09Z","timestamp":1770802209000},"update-policy":"https:\/\/doi.org\/10.4102\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Multimodal imaging in conductive hearing loss: Optimising CT, MRI and CTA for accurate diagnosis and management"],"prefix":"10.4102","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1992-2561","authenticated-orcid":false,"given":"Athanasios","family":"Vlachodimitropoulos","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03c3d1v10","id-type":"ROR","asserted-by":"publisher"}],"name":"General University Hospital of Patras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0592-6921","authenticated-orcid":false,"given":"Michail","family":"Athanasopoulos","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03c3d1v10","id-type":"ROR","asserted-by":"publisher"}],"name":"General University Hospital of Patras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3033-2687","authenticated-orcid":false,"given":"Afroditi","family":"Lepida","sequence":"additional","affiliation":[{"name":"Primary Health Care Center of Agios Alexios, Patras, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2249-7068","authenticated-orcid":false,"given":"Pinelopi","family":"Samara","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0315ea826","id-type":"ROR","asserted-by":"publisher"}],"name":"Children's Hospital Agia Sophia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6419-2107","authenticated-orcid":false,"given":"Ioannis E.","family":"Papachristos","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Biotypos, Chalandri, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1725-4806","authenticated-orcid":false,"given":"Theodoros","family":"Stathas","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03c3d1v10","id-type":"ROR","asserted-by":"publisher"}],"name":"General University Hospital of Patras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0642-6697","authenticated-orcid":false,"given":"Spyridon","family":"Lygeros","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03c3d1v10","id-type":"ROR","asserted-by":"publisher"}],"name":"General University Hospital of Patras"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5685-4999","authenticated-orcid":false,"given":"Georgios","family":"Batsaouras","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03c3d1v10","id-type":"ROR","asserted-by":"publisher"}],"name":"General University Hospital of Patras"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2580","published-online":{"date-parts":[[2026,2,12]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Zahnert T. The differential diagnosis of hearing loss. Dtsch Arztebl Int. 2011;108(25):433\u2013443; quiz 444. https:\/\/doi.org\/10.3238\/arztebl.2011.0433","DOI":"10.3238\/arztebl.2011.0433"},{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Merchant SN, Rosowski JJ. Conductive hearing loss caused by third-window lesions of the inner ear. Otol Neurotol. 2008;29(3):282\u2013289. https:\/\/doi.org\/10.1097\/mao.0b013e318161ab24","DOI":"10.1097\/MAO.0b013e318161ab24"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Touska P, Connor SEJ. Imaging of the temporal bone. Clin Radiol. 2020;75(9):658674. https:\/\/doi.org\/10.1016\/j.crad.2020.06.013","DOI":"10.1016\/j.crad.2020.06.013"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Cho IK, Jung JY, Yoo DS, Suh MW. 3-Dimensional reconstruction of the venous system in patients suffering from pulsatile tinnitus. Acta Otolaryngol. 2012;132(3):285\u2013289. https:\/\/doi.org\/10.3109\/00016489.2011.631190","DOI":"10.3109\/00016489.2011.631190"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Xu N, Ding H, Tang R, et al. Comparative study of the sensitivity of ultra-high-resolution CT and high-resolution CT in the diagnosis of isolated fenestral otosclerosis. Insights Imaging. 2023;14(1):211. https:\/\/doi.org\/10.1186\/s13244-023-01562-y","DOI":"10.1186\/s13244-023-01562-y"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Belden CJ, Weg N, Minor LB, Zinreich SJ. CT evaluation of bone dehiscence of the superior semicircular canal as a cause of sound- and\/or pressure-induced vertigo. Radiology. 2003;226(2):337\u2013343. https:\/\/doi.org\/10.1148\/radiol.2262010897","DOI":"10.1148\/radiol.2262010897"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Hahn Y, Diaz R, Hartman J, Bobinski M, Brodie H. Assessing stapes piston position using computed tomography: A cadaveric study. Otol Neurotol. 2009;30(2):223\u2013230. https:\/\/doi.org\/10.1097\/MAO.0b013e31818de5cd","DOI":"10.1097\/MAO.0b013e31818de5cd"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Uz Zaman S, Rangankar V, Muralinath K, Shah V, Gowtham K, Pawar R. Temporal bone cholesteatoma: Typical findings and evaluation of diagnostic utility on high resolution computed tomography. Cureus. 2022;14(3):e22730. https:\/\/doi.org\/10.7759\/cureus.22730","DOI":"10.7759\/cureus.22730"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Bar\u00e1th K, Huber AM, St\u00e4mpfli P, Varga Z, Kollias S. Neuroradiology of cholesteatomas. AJNR Am J Neuroradiol. 2011;32(2):221\u2013229. https:\/\/doi.org\/10.3174\/ajnr.A2052","DOI":"10.3174\/ajnr.A2052"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Lee TC, Aviv RI, Chen JM, Nedzelski JM, Fox AJ, Symons SP. CT grading of otosclerosis. 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AJR Am J Roentgenol. 2004;182(5):1305\u20131312. https:\/\/doi.org\/10.2214\/ajr.182.5.1821305","DOI":"10.2214\/ajr.182.5.1821305"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Thelen J, Bhatt AA. Multimodality imaging of paragangliomas of the head and neck. Insights Imaging. 2019;10(1):29. https:\/\/doi.org\/10.1186\/s13244-019-0701-2","DOI":"10.1186\/s13244-019-0701-2"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Deep NL, Besch-Stokes JG, Lane JI, Driscoll CLW, Carlson ML. Paget\u2019s disease of the temporal bone: A single-institution contemporary review of 27 patients. Otol Neurotol. 2017;38(6):907\u2013915. https:\/\/doi.org\/10.1097\/MAO.0000000000001430","DOI":"10.1097\/MAO.0000000000001430"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Amilibia E, P\u00e9rez-Grau M, Callejo \u00c0, Cuadras P, Roca-Ribas F, Puyalto P. CT assessment of otic capsule bone density in paget\u2019s disease of the temporal bone and its relationship with hearing loss. Otol Neurotol. 2021;42(6):e788\u2013e794. https:\/\/doi.org\/10.1097\/MAO.0000000000003077","DOI":"10.1097\/MAO.0000000000003077"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Nguyen T, Pulickal G, Singh A, Lingam R. Conductive hearing loss with a \u2018dry middle ear cleft\u2019 \u2013 A comprehensive pictorial review with CT. Eur J Radiol. 2019;110:74\u201380. https:\/\/doi.org\/10.1016\/j.ejrad.2018.11.024","DOI":"10.1016\/j.ejrad.2018.11.024"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Naumann IC, Porcellini B, Fisch U. Otosclerosis: Incidence of positive findings on high-resolution computed tomography and their correlation to audiological test data. Ann Otol Rhinol Laryngol. 2005;114(9):709\u2013716. https:\/\/doi.org\/10.1177\/000348940511400910","DOI":"10.1177\/000348940511400910"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Kanzara T, Virk JS. Diagnostic performance of high resolution computed tomography in otosclerosis. World J Clin Cases. 2017;5(7):286\u2013291. https:\/\/doi.org\/10.12998\/wjcc.v5.i7.286","DOI":"10.12998\/wjcc.v5.i7.286"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Marchioni D, Valerini S, Mattioli F, Alicandri-Ciufelli M, Presutti L. Radiological assessment of the sinus tympani: Temporal bone HRCT analyses and surgically related findings. Surg Radiol Anat. 2015;37(4):385\u2013392. https:\/\/doi.org\/10.1007\/s00276-014-1366-7","DOI":"10.1007\/s00276-014-1366-7"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Touska P, Connor SEJ. ESR Essentials: Imaging of middle ear cholesteatoma-practice recommendations by the European Society of Head and Neck Radiology. Eur Radiol. 2025;35(4):2053\u20132064. https:\/\/doi.org\/10.1007\/s00330-024-11021-x","DOI":"10.1007\/s00330-024-11021-x"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Gulati M, Gupta S, Prakash A, Garg A, Dixit R. HRCT imaging of acquired cholesteatoma: A pictorial review. Insights Imaging. 2019;10(1):92. https:\/\/doi.org\/10.1186\/s13244-019-0782-y","DOI":"10.1186\/s13244-019-0782-y"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Basson OJ, Van Lierop AC. The role of HRCT in the evaluation of patients with chronic otitis media. J Laryngol Otol. 2009;123(2):177\u201381.","DOI":"10.1017\/S0022215108002454"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"De Foer B, Vercruysse JP, Bernaerts A, et al. Middle ear cholesteatoma: Non-echo-planar diffusion-weighted MR imaging versus delayed gadolinium-enhanced T1-weighted MR imaging \u2013 Value in detection. Radiology. 2010;255(3):866\u2013872. https:\/\/doi.org\/10.1148\/radiol.10091140","DOI":"10.1148\/radiol.10091140"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"Lingam RK, Nash R, Majithia A, Kalan A, Singh A. Non-echoplanar diffusion weighted imaging in the detection of post-operative middle ear cholesteatoma: Navigating beyond the pitfalls to find the pearl. Insights Imaging. 2016;7(5): https:\/\/doi.org\/10.1007\/s13244-016-0516-3","DOI":"10.1007\/s13244-016-0516-3"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Choi DL, Gupta MK, Rebello R, Archibald JD. Cost-comparison analysis of diffusion weighted magnetic resonance imaging (DWMRI) versus second look surgery for the detection of residual and recurrent cholesteatoma. J Otolaryngol Head Neck Surg. 2019;48(1):58. https:\/\/doi.org\/10.1186\/s40463-019-0384-1","DOI":"10.1186\/s40463-019-0384-1"},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"Lin EP, Chin BB, Fishbein L, et al. Head and neck paragangliomas: An update on the molecular classification, state-of-the-art imaging, and management recommendations. Radiol Imaging Cancer. 2022;4(3):e210088. https:\/\/doi.org\/10.1148\/rycan.210088","DOI":"10.1148\/rycan.210088"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"Purohit B, Op de Beeck K, Hermans R. Role of MRI as first-line modality in the detection of previously undiagnosed otosclerosis: A single tertiary institute experience. Insights Imaging. 2020;11(1):71. https:\/\/doi.org\/10.1186\/s13244-020-00878-3","DOI":"10.1186\/s13244-020-00878-3"},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"Lazzerini F, Forli F, Capobianco S, et al. Current trends in imaging for otosclerosis and the potential role of photon-counting computed tomography. Acta Otorhinolaryngol Ital. 2025;45(Suppl. 1):S18\u2013S28. https:\/\/doi.org\/10.14639\/0392-100X-suppl.1_3-45-2025-A1335","DOI":"10.14639\/0392-100X-suppl.1_3-45-2025-A1335"},{"key":"ref29","doi-asserted-by":"crossref","unstructured":"Chang YS, Reinshagen KL. Radiologic evaluation of conductive hearing loss. Oper Tech Otolaryngol Head Neck Surg. 2024;35(4):18\u201325.","DOI":"10.1016\/j.otot.2024.01.003"},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Expert Panel on Neurological Imaging; Agarwal M, Juliano AF, et al. ACR Appropriateness Criteria\u00ae inflammatory ear disease. J Am Coll Radiol. 2025;22(5S):S300\u2013S318.","DOI":"10.1016\/j.jacr.2025.02.026"},{"key":"ref31","doi-asserted-by":"crossref","unstructured":"Revanth S, Nagadi AN, Murthy S, et al. Utility of Non-EPI DWI MRI imaging in cholesteatoma: The indian perspective. Indian J Otolaryngol Head Neck Surg. 2022;74(Suppl 3):3919\u20133926. https:\/\/doi.org\/10.1007\/s12070-021-02704-8","DOI":"10.1007\/s12070-021-02704-8"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"Lingam RK, Bassett P. A meta-analysis on the diagnostic performance of non-echoplanar diffusion-weighted imaging in detecting middle ear cholesteatoma: 10 years on. Otol Neurotol. 2017;38(4):521\u2013528. https:\/\/doi.org\/10.1097\/MAO.0000000000001353","DOI":"10.1097\/MAO.0000000000001353"},{"key":"ref33","doi-asserted-by":"crossref","unstructured":"Zhong S, Zuo W. An update on temporal bone paragangliomas. Curr Treat Options Oncol. 2023;24(10):1392\u20131407. https:\/\/doi.org\/10.1007\/s11864-023-01127-7","DOI":"10.1007\/s11864-023-01127-7"},{"key":"ref34","doi-asserted-by":"crossref","unstructured":"Neves F, Huwart L, Jourdan G, et al. Head and neck paragangliomas: Value of contrast-enhanced 3D MR angiography. AJNR Am J Neuroradiol. 2008;29(5):883\u2013889. https:\/\/doi.org\/10.3174\/ajnr.A0948","DOI":"10.3174\/ajnr.A0948"},{"key":"ref35","unstructured":"Van den Berg R, Verbist BM, Mertens BJ, Van der Mey AG, Van Buchem MA. Head and neck paragangliomas: Improved tumor detection using contrast-enhanced 3D time-of-flight MR angiography as compared with fat-suppressed MR imaging techniques. AJNR Am J Neuroradiol. 2004;25(5):863\u2013870."},{"key":"ref36","unstructured":"Krishnan A, Mattox DE, Fountain AJ, Hudgins PA. CT arteriography and venography in pulsatile tinnitus: Preliminary results. AJNR Am J Neuroradiol. 2006;27(8):1635\u20131638."},{"key":"ref37","doi-asserted-by":"crossref","unstructured":"Vangrinsven G, Bernaerts A, Deckers F, Van Dinther J, Zarowski A, De Foer B. Beyond the otoscope: An imaging review of congenital cholesteatoma. Insights Imaging. 2024;15(1):194. https:\/\/doi.org\/10.1186\/s13244-024-01761-1","DOI":"10.1186\/s13244-024-01761-1"},{"key":"ref38","doi-asserted-by":"crossref","unstructured":"Potsic WP, Samadi DS, Marsh RR, Wetmore RF. A staging system for congenital cholesteatoma. Arch Otolaryngol Head Neck Surg. 2002;128(9):1009\u20131012. https:\/\/doi.org\/10.1001\/archotol.128.9.1009","DOI":"10.1001\/archotol.128.9.1009"},{"key":"ref39","doi-asserted-by":"crossref","unstructured":"Wegner I, Van Waes AM, Bittermann AJ, et al. A systematic review of the diagnostic value of CT imaging in diagnosing otosclerosis. Otol Neurotol. 2016;37(1):9\u201315. https:\/\/doi.org\/10.1097\/MAO.0000000000000924","DOI":"10.1097\/MAO.0000000000000924"},{"key":"ref40","doi-asserted-by":"crossref","unstructured":"Singh VK, Badhwar S, D\u2019Souza J, Indrajit IK. Glomus tympanicum. Med J Armed Forces India. 2004;60(2):200\u2013203. https:\/\/doi.org\/10.1016\/S0377-1237(04)80125-4","DOI":"10.1016\/S0377-1237(04)80125-4"},{"key":"ref41","doi-asserted-by":"crossref","unstructured":"Rashma R, Kumar J, Garg A, et al. Low-dose versus standard-dose normal temporal bone CT in children: A comparison study. Egypt J Radiol Nucl Med. 2024;55:85. https:\/\/doi.org\/10.1186\/s43055-024-01254-7","DOI":"10.1186\/s43055-024-01254-7"},{"key":"ref42","doi-asserted-by":"crossref","unstructured":"Malviya S, Voepel-Lewis T, Eldevik OP, Rockwell DT, Wong JH, Tait AR. Sedation and general anaesthesia in children undergoing MRI and CT: Adverse events and outcomes. 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