{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:29:42Z","timestamp":1787761782040,"version":"build-2784847793"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:p>\n                    Sepsis is a clinical syndrome characterised by systemic inflammation due to infection. There is a spectrum with severity ranging from sepsis to severe sepsis and septic shock. Even with optimal treatment, mortality due to severe sepsis or septic shock is significant and poses a challenge to management. Antibiotics, source control, resuscitation with fluids, vasopressor and inotropic agents are the main-stay of treatment for septic shock. These may be supplemented with transfusion of red blood cells and or blood products, in the case of anaemia to sustain sufficient oxygen delivery\n                    <jats:sup>[1]<\/jats:sup>\n                    or to manage associated haematological issues. Transfusion in sepsis has always been a debatable issue, especially in relation to choice of the fluid and the role of blood or blood product transfusion.\n                  <\/jats:p>","DOI":"10.4103\/0019-5049.144676","type":"journal-article","created":{"date-parts":[[2014,11,13]],"date-time":"2014-11-13T09:13:59Z","timestamp":1415870039000},"page":"643-646","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Blood transfusion practices in sepsis"],"prefix":"10.4103","volume":"58","author":[{"given":"TVSP","family":"Murthy","sequence":"first","affiliation":[{"name":"Department of Anesthesia and Crtical Care, Command Hospital, Armed Forces Medical College, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20251205","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1001\/jama.288.12.1499","article-title":"Anaemia and blood transfusion in 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