{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:41:15Z","timestamp":1786653675446,"version":"build-2736575974"},"reference-count":43,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:p>Therapeutic transfusion techniques such as apheresis and phlebotomy are frequently used in intensive care units. Use of the apheresis technique for the treatment of various diseases in critically ill patients is growing day by day. There are increasing evidences for using apheresis as a primary therapy or as an adjunct to other therapies for various diseases such as thrombotic thrombocytopenic purpura, haemolytic uremic syndrome, drug toxicities, autoimmune disease, sepsis and fulminant hepatic failure. Apheresis is an invasive procedure. It has significant physiologic consequences, so the care of these patients requires continuous supervision. Phlebotomy is performed as an intervention for some disease management. Its use is nowadays restricted to conditions such as polycythaemia, haemochromatosis and porphyria cutanea tarda. In this review, we have looked at various indications, procedure and complications of apheresis and phlebotomy in critical care unit.<\/jats:p>","DOI":"10.4103\/0019-5049.144685","type":"journal-article","created":{"date-parts":[[2014,11,13]],"date-time":"2014-11-13T09:13:59Z","timestamp":1415870039000},"page":"672-678","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["Role of therapeutic apheresis and phlebotomy techniques in anaesthesia and critical care"],"prefix":"10.4103","volume":"58","author":[{"given":"Neeta","family":"Bose","sequence":"first","affiliation":[{"name":"Department of Anesthesia, Gujarat Medical Education and Research Society, Gotri, Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitendra","family":"Kanzariya","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, PSMC, Karamsad, Anand, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-20251205","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/j.1744-9987.1997.tb00143.x","article-title":"Efficacy and limitation of apheresis therapy in critical care","volume":"1","author":"Hirasawa","year":"1997","journal-title":"Ther Apher"},{"key":"R3-20251205","doi-asserted-by":"crossref","first-page":"789","DOI":"10.7326\/0003-4819-58-5-789","article-title":"Plasmapheresis therapy in macroglobulinemia","volume":"58","author":"Solomon","year":"1963","journal-title":"Ann Intern Med"},{"key":"R4-20251205","doi-asserted-by":"crossref","first-page":"377","DOI":"10.3181\/00379727-80-19629","article-title":"A method of human plasmapheresis","volume":"80","author":"Adams","year":"1952","journal-title":"Proc Soc Exp Biol Med"},{"key":"R6-20251205","doi-asserted-by":"crossref","first-page":"3676","DOI":"10.1182\/blood.V86.10.3676.bloodjournal86103676","article-title":"Surgery and anesthesia in sickle cell disease. 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