{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:48:14Z","timestamp":1787071694218,"version":"build-2736575974"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:p>We describe for the first time, the perioperative care of a patient with a rare combination of Eisenmenger syndrome with \u03b2-thalassemia major presenting for splenectomy. Patients with Eisenmenger syndrome have polycythemia because of chronic hypoxia but our patient was anaemic and had thrombocytopenia because of thalassemia major. The management of such a case can be challenging for any anaesthesiologist because of severe V\/Q mismatch (high shunt fraction and restrictive lung disease because of hypersplenism), decreased oxygen carrying capacity (anaemia) and increased risk of haemorrhage (thrombocytopenia), along with the potential increase in intracardiac shunt during anaesthesia.<\/jats:p>","DOI":"10.4103\/0019-5049.79892","type":"journal-article","created":{"date-parts":[[2011,5,7]],"date-time":"2011-05-07T10:43:39Z","timestamp":1304765019000},"page":"187-189","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Anaesthetic management of a patient with Eisenmenger syndrome and \u03b2-thalassemia major for splenectomy"],"prefix":"10.4103","volume":"55","author":[{"given":"Nishkarsh","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, PGIMER and Associated Dr. RML Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarbjot","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, PGIMER and Associated Dr. RML Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Goila","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, PGIMER and Associated Dr. RML Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mridula","family":"Pawar","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, PGIMER and Associated Dr. RML Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20251205","doi-asserted-by":"crossref","first-page":"9049","DOI":"10.1007\/BF03011038","article-title":"The anaesthetic management of the child with Eisenmenger syndrome","volume":"42","author":"Lyons","year":"1995","journal-title":"Can J Anaesth"},{"key":"R2-20251205","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/s00540-005-0328-y","article-title":"Anesthetic management of a patient with beta-thalassemia intermedia undergoing splenectomy","volume":"9","author":"Kitoh","year":"2005","journal-title":"J Anesth"},{"key":"R4-20251205","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1213\/00000539-199306000-00028","article-title":"Anesthetic implications of adults with congenital heart disease","volume":"76","author":"Baum","year":"1993","journal-title":"Anesth Analg"},{"key":"R5-20251205","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/S0735-1097(98)00554-3","article-title":"Noncardiac surgery in Eisenmenger syndrome","volume":"33","author":"Ammash","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"R6-20251205","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1053\/j.jvca.2004.11.019","article-title":"Tetralogy of Fallot repair in a patient with betathalassemia major","volume":"19","author":"Venugopal","year":"2005","journal-title":"J Cardiothorac VascAnesth"}],"container-title":["Indian Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01762628-201155020-00020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:51:16Z","timestamp":1787068276000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01762628-201155020-00020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.4103\/0019-5049.79892","relation":{},"ISSN":["0019-5049","0976-2817"],"issn-type":[{"value":"0019-5049","type":"print"},{"value":"0976-2817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}