{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T03:41:45Z","timestamp":1792381305746,"version":"4.4.0"},"reference-count":28,"publisher":"Medknow","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Dermatol"],"published-print":{"date-parts":[[2013]]},"DOI":"10.4103\/0019-5154.113947","type":"journal-article","created":{"date-parts":[[2013,6,25]],"date-time":"2013-06-25T07:39:52Z","timestamp":1372145992000},"page":"326","source":"Crossref","is-referenced-by-count":6,"title":["The evaluation of the impact of age, skin tags, metabolic syndrome, body mass index, and smoking on homocysteine, endothelin-1, high-sensitive C-reactive protein, and on the heart"],"prefix":"10.4103","volume":"58","author":[{"given":"OmarSoliman","family":"El Safoury","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwa","family":"Ezzat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MahmoudF","family":"Abdelhamid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Shoukry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehssan","family":"Badawy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2581","reference":[{"key":"key-10.4103\/0019-5154.113947-1","first-page":"393","volume-title":"A clinical evaluation of skin tags in relation to obesity, type 2 diabetes mellitus, age, and sex","author":"El","year":"2011","journal-title":"Indian J Dermatol","ISSN":"https:\/\/id.crossref.org\/issn\/0019-5154","issn-type":"print"},{"key":"key-10.4103\/0019-5154.113947-2","first-page":"180","volume-title":"Skin tags: Localization and frequencies according to sex and age","author":"Banik","year":"1987","journal-title":"Dermatologica"},{"key":"key-10.4103\/0019-5154.113947-3","first-page":"577","volume-title":"Skin tags, leptin, metabolic syndrome and change of the life style","author":"El","year":"2011","journal-title":"Indian J Dermatol Venereol Leprol","ISSN":"https:\/\/id.crossref.org\/issn\/0378-6323","issn-type":"print"},{"key":"key-10.4103\/0019-5154.113947-4","first-page":"25","volume-title":"Association between skin tags and insulin resistance","author":"Tamega","year":"2010","journal-title":"An Bras Dermatol"},{"key":"key-10.4103\/0019-5154.113947-5","first-page":"599","volume-title":"Homocysteine determinants and the evidence to what extent homocysteine determines the risk of coronary heart disease","author":"De","year":"2002","journal-title":"Pharmacol Rev"},{"key":"key-10.4103\/0019-5154.113947-6","first-page":"1374","volume-title":"Plasma total homocysteine and hospitalizations for cardiovascular disease: The Hordaland Homocysteine Study","author":"Nurk","year":"2002","journal-title":"Arch Intern Med"},{"key":"key-10.4103\/0019-5154.113947-7","first-page":"1203","volume-title":"Homocysteine level and coronary heart disease incidence: A systematic review and meta-analysis","author":"Humphrey","year":"2008","journal-title":"Mayo Clin Proc"},{"key":"key-10.4103\/0019-5154.113947-8","doi-asserted-by":"crossref","unstructured":"Brunner H, Cockcroft JR, Deanfield J, Donald A, Ferrannini E, Halcox J, et al. Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension. J Hypertens 2005;23:233-46.","DOI":"10.1097\/00004872-200502000-00001"},{"key":"key-10.4103\/0019-5154.113947-9","first-page":"621","volume-title":"Mechanisms of ET-1-induced endothelial dysfunction","author":"Iglarz","year":"2007","journal-title":"J Cardiovasc Pharmacol"},{"key":"key-10.4103\/0019-5154.113947-10","first-page":"415","volume-title":"C-reactive protein levels and coronary artery disease incidence and mortality in apparently healthy men and women: The EPIC-Norfolk prospective population study 1993-2003","author":"Boekholdt","year":"2006","journal-title":"Atherosclerosis"},{"key":"key-10.4103\/0019-5154.113947-11","first-page":"19","volume-title":"Association of high sensitive C-reactive protein (hsCRP) with established cardiovascular risk factors in the Indian population","author":"Jeemon","year":"2011","journal-title":"Nutr Metab (Lond)"},{"key":"key-10.4103\/0019-5154.113947-12","first-page":"499","volume-title":"Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association","author":"Pearson","year":"2003","journal-title":"Circulation"},{"key":"key-10.4103\/0019-5154.113947-13","first-page":"433","volume-title":"Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute\/American Heart Association conference on scientific issues related to definition","author":"Grundy","year":"2004","journal-title":"Circulation"},{"key":"key-10.4103\/0019-5154.113947-14","first-page":"88","volume-title":"Metabolic syndrome and endothelial dysfunction","author":"Fornoni","year":"2005","journal-title":"Curr Hypertens Rep"},{"key":"key-10.4103\/0019-5154.113947-15","first-page":"265","volume-title":"Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: Alterations with plasma homocysteine and pyridoxal 5\u2032-phosphate concentrations","author":"Melnyk","year":"2000","journal-title":"Clin Chem"},{"key":"key-10.4103\/0019-5154.113947-16","first-page":"271","volume-title":"Relationships between plasma levels of type-II phospholipase A2, PAF-acetylhydrolase, leukotriene B4, complements, endothelin-1, and thrombomodulin in patients with sepsis","author":"Takakuwa","year":"1994","journal-title":"Res Commun Chem Pathol Pharmacol"},{"key":"key-10.4103\/0019-5154.113947-17","first-page":"1839","volume-title":"Development and validation of an automated and ultrasensitive immunoturbidimetric assay for C-reactive protein","author":"Borque","year":"2000","journal-title":"Clin Chem"},{"key":"key-10.4103\/0019-5154.113947-18","first-page":"433","volume-title":"Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute\/American Heart Association conference on scientific issues related to definition","author":"Grundy","year":"2004","journal-title":"Circulation"},{"key":"key-10.4103\/0019-5154.113947-19","first-page":"1079","volume-title":"The pathogenesis of coronary artery disease.A possible role for methionine metabolism","author":"Wilcken","year":"1976","journal-title":"J Clin Invest"},{"key":"key-10.4103\/0019-5154.113947-20","first-page":"2426","volume-title":"Endothelin in coronary endothelial dysfunction and early atherosclerosis in humans","author":"Lerman","year":"1995","journal-title":"Circulation"},{"key":"key-10.4103\/0019-5154.113947-21","first-page":"193","volume-title":"The metabolic profile in patients with skin tags","author":"Sari","year":"2010","journal-title":"Clin Exp Med"},{"key":"key-10.4103\/0019-5154.113947-22","first-page":"20","volume-title":"A study of androgen and estrogen receptors alpha, beta in skin tags","author":"El","year":"2010","journal-title":"Indian J Dermatol","ISSN":"https:\/\/id.crossref.org\/issn\/0019-5154","issn-type":"print"},{"key":"key-10.4103\/0019-5154.113947-23","first-page":"577","volume-title":"Skin tags, leptin, metabolic syndrome and change of the life style","author":"El","year":"2011","journal-title":"Indian J Dermatol Venereol Leprol","ISSN":"https:\/\/id.crossref.org\/issn\/0378-6323","issn-type":"print"},{"key":"key-10.4103\/0019-5154.113947-24","first-page":"1552","volume-title":"Assessment of serum leptin, insulin resistance and metabolic syndrome in patients with skin tags","author":"Shaheen","year":"2012","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"key-10.4103\/0019-5154.113947-25","first-page":"873","volume-title":"Skin tags and the atherogenic lipid profile","author":"Crook","year":"2000","journal-title":"J Clin Pathol"},{"key":"key-10.4103\/0019-5154.113947-26","first-page":"371","volume-title":"Skin tags and atherosclerotic risk factors","author":"Erdo\u00f0an","year":"2005","journal-title":"J Dermatol"},{"key":"key-10.4103\/0019-5154.113947-27","first-page":"226","volume-title":"Acrochordon, diabetes and associations","author":"Bhargava","year":"1996","journal-title":"Indian J Dermatol Venereol Leprol","ISSN":"https:\/\/id.crossref.org\/issn\/0378-6323","issn-type":"print"},{"key":"key-10.4103\/0019-5154.113947-28","first-page":"299","volume-title":"Dermatoses in 156 obese adults","author":"Garc\u00eda-Hidalgo","year":"1999","journal-title":"Obes Res"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T11:11:34Z","timestamp":1498043494000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.e-ijd.org\/text.asp?2013\/58\/4\/326\/113947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013]]}},"alternative-id":["113947"],"URL":"https:\/\/doi.org\/10.4103\/0019-5154.113947","relation":{},"ISSN":["0019-5154"],"issn-type":[{"value":"0019-5154","type":"print"}],"subject":[],"published":{"date-parts":[[2013]]}}}