{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:35:02Z","timestamp":1787841302769,"version":"build-2784847793"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Phototherapy is one of the most effective treatment options in vitiligo. Targeted phototherapy devices are becoming more popular as they offer a lot of advantages over the conventional whole-body phototherapy units.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims and Objectives:<\/jats:title>\n                    <jats:p>The present study was conducted to assess the efficacy and safety of a targeted narrowband ultraviolet B (NBUVB) device in vitiligo.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A total of 40 patients of vitiligo were treated with a targeted NBUVB device twice-weekly for a maximum of 30 sessions or until 100% repigmentation, whichever was reached first. The extent of repigmentation achieved was assessed and adverse effects, if any, were also noted down.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      There were 31 responders (77.5%) who achieved repigmentation ranging from 50% to 100%. The onset of repigmentation was seen as early as the 3\n                      <jats:sup>rd<\/jats:sup>\n                      dose in some cases and by the 10\n                      <jats:sup>th<\/jats:sup>\n                      dose in all responders. A total of 97 lesions were treated out of which 45 lesions (46.6%) achieved 90-100% repigmentation. Lesions showing 75% and 50% repigmentation were 14 and 15 in number respectively. 23 lesions failed to show any significant repigmentation at the end of 30 doses. Best response was seen on the face and neck with 20 of the 31 lesions achieving 90-100% repigmentation in this area. Duration of vitiligo was seen to have no statistically significant impact on the repigmentation achieved.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Targeted NBUVB phototherapy seems to be an effective treatment option in localized vitiligo with a rapid onset of repigmentation seen as early as 2\n                      <jats:sup>nd<\/jats:sup>\n                      week of treatment.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0019-5154.139892","type":"journal-article","created":{"date-parts":[[2014,9,2]],"date-time":"2014-09-02T08:29:26Z","timestamp":1409646566000},"page":"485-489","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["Efficacy of Targeted Narrowband Ultraviolet B Therapy in Vitiligo"],"prefix":"10.4103","volume":"59","author":[{"given":"Imran","family":"Majid","sequence":"first","affiliation":[{"name":"From the Department of Dermatology, Government Medical College, Srinagar, Jammu and Kashmir, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250920","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1468-3083.2005.01369.x","article-title":"Psychosocial effects of vitiligo","volume":"20","author":"Ongenae","year":"2006","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"R2-20250920","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1046\/j.1468-3083.2002.00590.x","article-title":"Psychiatric morbidity in vitiligo: Prevalence and correlates in India","volume":"16","author":"Mattoo","year":"2002","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"R3-20250920","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1111\/j.1365-2230.1996.tb00116.x","article-title":"Factors affecting responses on dermatology life quality index items among vitiligo sufferers","volume":"21","author":"Kent","year":"1996","journal-title":"Clin Exp Dermatol"},{"key":"R4-20250920","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1067\/mjd.2001.114752","article-title":"Narrow-band ultraviolet B is a useful and well-tolerated treatment for vitiligo","volume":"44","author":"Scherschun","year":"2001","journal-title":"J Am Acad Dermatol"},{"key":"R5-20250920","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0190-9622(00)90133-6","article-title":"Treatment of generalized vitiligo in children with narrow-band (TL-01) UVB radiation therapy","volume":"42","author":"Njoo","year":"2000","journal-title":"J Am Acad Dermatol"},{"key":"R6-20250920","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.det.2004.11.001","article-title":"Using light in dermatology: An update on lasers, ultraviolet phototherapy, and photodynamic therapy","volume":"23","author":"Hamzavi","year":"2005","journal-title":"Dermatol Clin"},{"key":"R7-20250920","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1111\/j.1468-3083.2006.01546.x","article-title":"Combination of narrow band UVB and topical calcipotriol for the treatment of vitiligo","volume":"20","author":"Goktas","year":"2006","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"R8-20250920","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1365-2230.2005.02037.x","article-title":"Tacalcitol and narrow-band phototherapy in patients with vitiligo","volume":"31","author":"Leone","year":"2006","journal-title":"Clin Exp Dermatol"},{"key":"R9-20250920","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/j.1600-0781.2010.00540.x","article-title":"Does topical tacrolimus ointment enhance the efficacy of narrowband ultraviolet B therapy in vitiligo? 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