{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T23:57:23Z","timestamp":1789257443957,"version":"build-2803163510"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:p>Rabson-Mendenhall syndrome (RMS) is a rare genetic disorder characterized by growth retardation, dysmorphisms, lack of subcutaneous fat, acanthosis nigricans, enlarged genitalia, hirsutism, dysplastic dentition, coarse facial features, abnormal glucose homeostasis, hyperinsulinemia and pineal hyperplasia. Herein, we describe a 13-year-old girl with physical features of RMS who presented to us on account of acanthosis nigricans.<\/jats:p>","DOI":"10.4103\/0019-5154.143579","type":"journal-article","created":{"date-parts":[[2014,10,29]],"date-time":"2014-10-29T03:05:15Z","timestamp":1414551915000},"page":"633-633","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Rabson-Mendenhall Syndrome"],"prefix":"10.4103","volume":"59","author":[{"given":"Iffat","family":"Hassan","sequence":"first","affiliation":[{"name":"From the Department of Dermatology, STD and Leprosy SMHS Hospital, Government Medical College, Srinagar, Jammu and Kashmir, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hinah","family":"Altaf","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, STD and Leprosy SMHS Hospital, Government Medical College, Srinagar, Jammu and Kashmir, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atiya","family":"Yaseen","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, STD and Leprosy SMHS Hospital, Government Medical College, Srinagar, Jammu and Kashmir, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250921","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1093\/ajcp\/26.3.283","article-title":"Familial hypertrophy of pineal body, hyperplasia of adrenal cortex and diabetes mellitus; report of 3 cases","volume":"26","author":"Rabson","year":"1956","journal-title":"Am J Clin Pathol"},{"key":"R2-20250921","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1136\/adc.50.9.703","article-title":"Familial insulin resistant diabetes, multiple somatic anomalies, and pineal hyperplasia","volume":"50","author":"West","year":"1975","journal-title":"Arch Child Dis"},{"key":"R3-20250921","first-page":"799","article-title":"Impaired growth in Rabson-Mendenhall syndrome: Lack of effect of growth hormone and insulin-like growth factor I","volume":"79","author":"Longo","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"key":"R4-20250921","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1023\/A:1012411709972","article-title":"Decreased half-life of insulin-like growth factor I in Rabson-Mendenhall syndrome","volume":"24","author":"Longo","year":"2001","journal-title":"J Inherit Metab Dis"},{"key":"R5-20250921","first-page":"1","article-title":"Rabson Mendenhall Syndrome: A case report","volume":"4","author":"Alaei Mohammad","year":"2010","journal-title":"Iran J Child Neurol"},{"key":"R6-20250921","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1093\/hmg\/11.12.1465","article-title":"Genotype-phenotype correlation in inherited severe insulin resistance","volume":"11","author":"Longo","year":"2002","journal-title":"Hum Mol Genet"},{"key":"R7-20250921","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1097\/01.md.0000133625.73570.54","article-title":"Clinical course of genetic diseases of the insulin receptor (Type A and Rabson-Mendenhall syndromes): A 30-year prospective","volume":"83","author":"Musso","year":"2004","journal-title":"Medicine (Baltimore)"},{"key":"R8-20250921","doi-asserted-by":"crossref","first-page":"70","DOI":"10.4103\/0019-5359.13906","article-title":"Rabson-Mendenhall syndrome","volume":"59","author":"Kumar","year":"2005","journal-title":"Indian J Med Sci"},{"key":"R9-20250921","doi-asserted-by":"crossref","first-page":"499","DOI":"10.4103\/0019-5154.103077","article-title":"Leprechaunism: A case report","volume":"57","author":"Sen","year":"2012","journal-title":"Indian J Dermatol"},{"key":"R10-20250921","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1210\/jc.2003-031952","article-title":"Efficacy of recombinant methionyl human leptin therapy for the extreme insulin resistance of the Rabson Mendenhall syndrome","volume":"89","author":"Cochran","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"R11-20250921","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1111\/j.1365-4632.2008.03591.x","article-title":"Rabson-Mendenhall syndrome","volume":"47","author":"Parveen","year":"2008","journal-title":"Int J Dermatol"},{"key":"R12-20250921","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s10266-009-0106-7","article-title":"Sameena Parveen. Rabson-Mendenhall syndrome: Two case reports and a brief review of the literature","volume":"98","author":"Bathi","year":"2010","journal-title":"Odontology"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00076423-201459060-00045","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:43:02Z","timestamp":1787067782000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00076423-201459060-00045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.4103\/0019-5154.143579","relation":{},"ISSN":["0019-5154","1998-3611"],"issn-type":[{"value":"0019-5154","type":"print"},{"value":"1998-3611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"2012-06-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-11-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}