{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:39:29Z","timestamp":1787071169609,"version":"build-2736575974"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:p>\n                    A 40-year-old male human immunodeficiency virus (HIV) -positive patient on highly active antiretroviral therapy (HAART) developed bilateral cervical lymphadenopathy with fine needle aspiration cytology (FNAC) showing yeast cells of\n                    <jats:italic toggle=\"yes\">Penicillium marneffei<\/jats:italic>\n                    . The adenopathy disappeared after 9 months of itraconazole therapy at a dose of 200 mg\/day. Seven years later and 2 days following second-line HAART, the patient presented with generalized papulonodules and ulceronecrotic lesions. Biopsy of the skin lesion revealed plenty of yeast forms dividing by binary fission morphologically resembling\n                    <jats:italic toggle=\"yes\">Penicillium marneffei<\/jats:italic>\n                    . Significant improvement was observed at 2 weeks of starting itraconazole 400 mg\/day. After 3 months, the dose was reduced to 200 mg\/day and advised to continue for 6 months. Penicillosis presenting initially in the form of cervical adenopathy and later, developing typical skin lesions rapidly progressing to ulcerative and necrotic erosions may be due to continued immunosuppression followed by immune reconstitution inflammatory syndrome (IRIS).\n                  <\/jats:p>","DOI":"10.4103\/0019-5154.152607","type":"journal-article","created":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T19:02:31Z","timestamp":1758481351000},"page":"215-215","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Ulceronecrotic Penicillosis"],"prefix":"10.4103","volume":"60","author":[{"given":"Romita","family":"Bachaspatimayum","sequence":"first","affiliation":[{"name":"From the Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Science, Imphal, Manipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thangjamang","family":"Haokip","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Science, Imphal, Manipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Zamzachin","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Science, Imphal, Manipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanglem Elizabeth","family":"Devi","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Science, Imphal, Manipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-20250921","first-page":"71","article-title":"Penicillosis marneffei infection in Non-HIV-infected patients","volume":"28","author":"Plongla","year":"2011","journal-title":"J Infect Dis Antimicrob Agents"},{"key":"R3-20250921","doi-asserted-by":"crossref","first-page":"2","DOI":"10.5070\/D36J96F72F","article-title":"Penicillium marneffei infection in an African man","volume":"16","author":"Yap","year":"2010","journal-title":"Dermatol Online J"},{"key":"R5-20250921","doi-asserted-by":"crossref","first-page":"e78","DOI":"10.1086\/318703","article-title":"First Cases of Disseminated Penicilliosis Marneffei Infection among Patients with Acquired Immunodeficiency Syndrome in Vietnam","volume":"32","author":"Hien","year":"2001","journal-title":"Clin Infect Dis"},{"key":"R6-20250921","article-title":"Penicillium marneffei infection in AIDS","author":"Wong","year":"2011","journal-title":"Patholog Res Int 2011"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00076423-201560020-00055","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:42:32Z","timestamp":1787067752000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00076423-201560020-00055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3]]},"references-count":4,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.4103\/0019-5154.152607","relation":{},"ISSN":["0019-5154","1998-3611"],"issn-type":[{"value":"0019-5154","type":"print"},{"value":"1998-3611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3]]},"assertion":[{"value":"2013-07-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}