{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:34:48Z","timestamp":1786649688480,"version":"build-2736575974"},"reference-count":87,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:p>Acne Vulgaris is one of the most common skin disorders which dermatologists have to treat. It mainly affect adolescent, though may present at any age. In recent years, due to better understanding of the pathogenesis of acne, new therapeutic modalities and various permutation and combinations have been designed. In topical agents; benzoyl peroxide, antibiotics, retinoids, etc are the mainstay of treatment; can be given in combinations. While systemic therapy includes oral antibiotics, hormonal therapy, and isotretinoin, depending upon the need of patients it has to be selected. Physical treatment in the form of lesion removal, photo-therapy is also helpful in few of them. Since various old and new topical and systemic agents are available to treat acne, it sometime confuse treating dermatologist. To overcome this, panel of physicians and researchers worked together as a global alliance and task force to improve outcomes in acne treatment. They have tried to give consensus recommendation for the treatment of acne. Successful management of acne needs careful selection of anti-acne agents according to clinical presentation and individual patient needs.<\/jats:p>","DOI":"10.4103\/0019-5154.77543","type":"journal-article","created":{"date-parts":[[2011,3,11]],"date-time":"2011-03-11T01:04:45Z","timestamp":1299805485000},"page":"7-13","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":77,"title":["ACNE VULGARIS TREATMENT: THE CURRENT SCENARIO"],"prefix":"10.4103","volume":"56","author":[{"given":"Sanjay K","family":"Rathi","sequence":"first","affiliation":[{"name":"Consultant Dermatologist, Siliguri, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20260605","first-page":"43.1","article-title":"Disorders of the sebaceous glands","author":"Simpson","year":"2004","journal-title":"Rook's Text book of Dermatology"},{"key":"R2-20260605","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1111\/j.1346-8138.1991.tb03122.x","article-title":"Pathogenesis and pathognesis-related treatment of acne","volume":"18","author":"Gollnick","year":"1991","journal-title":"J Dermatol"},{"key":"R3-20260605","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/0190-9622(95)90416-6","article-title":"New understanding of the pathogenesis of acne","volume":"32","author":"Leyden","year":"1995","journal-title":"J Am Acad Dermatol"},{"key":"R6-20260605","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1365-4362.1996.tb01644.x","article-title":"Treatment of acne vulgaris: Combination of 3% erythromycin and 5% benzoyl peroxide in a gel compared to clindamycin phosphate lotion","volume":"35","author":"Packman","year":"1996","journal-title":"Int J Dermatol"},{"key":"R8-20260605","first-page":"263","article-title":"Water-based versus alcohol-based benzoyl peroxide preparations in the treatment of acne vulgaris","volume":"172","author":"Fyrand","year":"1986","journal-title":"Dermatologica"},{"key":"R9-20260605","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1111\/j.1365-4362.1986.tb04534.x","article-title":"Comparing 2.5%, 5% and 10% benzoyl peroxide on inflammatory acne vulgaris","volume":"25","author":"Mills","year":"1986","journal-title":"Int J Dermatol"},{"key":"R10-20260605","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/j.1365-2133.1995.tb05014.x","article-title":"The short term treatment of acne vulgaris with benzoyl peroxide: Effects on the surface and follicular cutaneous microflora","volume":"132","author":"Bojor","year":"1995","journal-title":"Br J Dermatol"},{"key":"R11-20260605","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3109\/09546639009086737","article-title":"Topical antibiotics for the treatment of acne vulgaris: A critical evaluation of the literature on their clinical benefit and comparative efficacy","volume":"1","author":"Eady","year":"1990","journal-title":"J Dermatol Treat"},{"key":"R12-20260605","first-page":"106","article-title":"Comparison of two concentrations of tretinoin solution in the topical treatment of acne vulgaris","volume":"216","author":"Krishnan","year":"1976","journal-title":"Practitioner"},{"key":"R13-20260605","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/S0190-9622(96)90443-0","article-title":"A comparison of the efficacy and safety of adapalene gel 0.1% and tretinoin gel 0.025% in the treatment of acne vulgaris: A multicentric trial","volume":"34","author":"Shalita","year":"1996","journal-title":"J Am Acad Dermatol"},{"key":"R14-20260605","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.clinthera.2005.02.009","article-title":"Topical tretinoin in inflammatory acne: A retrospective, investigator-blinded, vehicle-controlled, photographic assessment","volume":"27","author":"Leyden","year":"2005","journal-title":"Clin Ther"},{"key":"R15-20260605","first-page":"14","article-title":"The mechanism of topical retinoids","volume":"75","author":"Kang","year":"2005","journal-title":"Cutis"},{"key":"R16-20260605","doi-asserted-by":"crossref","first-page":"4323","DOI":"10.1016\/j.bmc.2006.02.041","article-title":"Retinoic acid metabolism blocking agents (RAMBAs) for treatment of cancer and dermatological disease","volume":"14","author":"Njar","year":"2006","journal-title":"Bioorg Med Chem"},{"key":"R17-20260605","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.clindermatol.2004.03.009","article-title":"Acne; 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