{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:30:27Z","timestamp":1787758227043,"version":"build-2784847793"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:p>Vulvo-perineal Crohn's disease is a rare condition either when it is isolated or associated with digestive manifestations. In the former condition named metastatic Crohn's disease, it may constitute a diagnostic challenge and may be confused especially with other infectious or inflammatory disorders. We report a case of vulvo-perineal Crohn's disease in a 46-year-old woman. A 46-year-old woman was diagnosed with a vulvo-perineal Crohn's disease without digestive involvement. There was a chronic edema of the vulva with linear ulcerations on the inguino-crural regions and the buttocks fold, of 3 years. Treatment with metronidazole (1 g\/day for 6 months) led to almost complete healing of the ulcerations with a sustained result. Physicians must be aware of the diverse manifestations and confusing presentations of vulvo-perineal Crohn's disease.<\/jats:p>","DOI":"10.4103\/0019-5154.77568","type":"journal-article","created":{"date-parts":[[2011,3,11]],"date-time":"2011-03-11T01:04:45Z","timestamp":1299805485000},"page":"101-103","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["CHRONIC LINEAR ULCERATIONS OF THE INGUINO-CRURAL AND BUTTOCKS FOLDS"],"prefix":"10.4103","volume":"56","author":[{"given":"Aida","family":"Khaled","sequence":"first","affiliation":[{"name":"Department of Dermatology, Charles Nicolle Hospital - Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Ezzine-Sebai","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Charles Nicolle Hospital - Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Becima","family":"Fazaa","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Charles Nicolle Hospital - Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faten","family":"Zeglaoui","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Charles Nicolle Hospital - Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachida","family":"Zermani","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Charles Nicolle Hospital - Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Ridha","family":"Kamoun","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Charles Nicolle Hospital - Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20260605","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1007\/BF02236866","article-title":"Metastatic Crohn's disease: case report of an unusual variant and review of the literature","volume":"43","author":"Guest","year":"2000","journal-title":"Dis Colon Rectum"},{"key":"R2-20260605","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0151-9638(06)70969-3","article-title":"Vulvar involvement in Crohn's disease: efficacy of metronidazole","volume":"133","author":"Conscience","year":"2006","journal-title":"Ann Dermatol Venereol"},{"key":"R3-20260605","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1159\/000069963","article-title":"Thalidomide in refractory vulvar ulcerations associated with Crohn's disease","volume":"206","author":"Kolivras","year":"2003","journal-title":"Dermatology"},{"key":"R4-20260605","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1365-2230.2006.02079.x","article-title":"Treatment of vulval Crohn's disease with infliximab","volume":"31","author":"Preston","year":"2006","journal-title":"Clin Exp Dermatol"},{"key":"R5-20260605","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/0016-5085(80)90402-3","article-title":"Healing of perineal Crohn's disease with metronidazole","volume":"79","author":"Bernstein","year":"1980","journal-title":"Gastroenterology"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00076423-201156010-00026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:09:29Z","timestamp":1787756969000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00076423-201156010-00026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.4103\/0019-5154.77568","relation":{},"ISSN":["0019-5154","1998-3611"],"issn-type":[{"value":"0019-5154","type":"print"},{"value":"1998-3611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1]]},"assertion":[{"value":"2009-01-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-07-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}