{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T11:10:09Z","timestamp":1791803409163,"version":"4.3.4"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:p>\n                    Folliculitis et perifolliculitis capitis abscedens et suffodiens is a rare disease of unknown etiology. It is a suppurative process that involves the scalp, eventually resulting in extensive scarring and irreversible alopecia. The condition is also known as \u2018acne necrotica miliaris\u2019 or \u2018Proprionibacterium\u2019 folliculitis. Most often the disease affects men of African-American or African-Caribbean descent between 20 and 40 years of age. The clinical picture is determined by fluctuating painful fistule-forming conglomerates of abscesses in the region of the occipital scalp. The cause of scalp folliculitis is not well understood. It is generally considered to be an inflammatory reaction to components of the hair follicle, particularly the micro-organisms. These include: bacteria (especially Propionibacterium acnes, but in severe cases, also\n                    <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                    ), Yeasts (Malassezia species) and mites (Demodex folliculorum). The initial histopathologic finding is an exclusively neutrophilic infiltration followed by a granulomatous infiltrate. The treatment of the disease is usually difficult and often disappointing. Successful treatment with isotretinoin 1 mg\/kg body mass could be achieved only after regular systematic administration in the course of 3-4 months. Here we describe a patient with eruptive purulent form of the disease, which has been controlled with combination therapy: systemic antibiosis with metronidazole and clindamycin, dermatosurgical removal of single nodular formations, and isotretinoin 1 mg\/kg body mass for 3-5 months.\n                  <\/jats:p>","DOI":"10.4103\/0019-5154.82492","type":"journal-article","created":{"date-parts":[[2011,6,30]],"date-time":"2011-06-30T00:54:09Z","timestamp":1309395249000},"page":"318-320","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":27,"title":["FOLLICULITIS ET PERIFOLLICULITIS CAPITIS ABSCEDENS ET SUFFODIENS CONTROLLED WITH A COMBINATION THERAPY: SYSTEMIC ANTIBIOSIS (METRONIDAZOLE PLUS CLINDAMYCIN), DERMATOSURGICAL APPROACH, AND HIGH-DOSE ISOTRETINOIN"],"prefix":"10.4103","volume":"56","author":[{"given":"Georgi","family":"Tchernev","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology, Trakian University, Medical Faculty, Stara Zagora, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250920","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1159\/000242207","article-title":"Dermatitis follicularis et perifollicularis conglobata","volume":"10","author":"Spritzer","year":"1903","journal-title":"Dermatol Zeitschrift"},{"key":"R2-20250920","first-page":"122","article-title":"Folliculitis et perifolliculitis capitis abscedens et suffodiens: case presentation","volume":"15","author":"Hoffmann","year":"1908","journal-title":"Dermatol Zeitschrift"},{"key":"R3-20250920","first-page":"617","article-title":"Systemic inflammatory reactions and extracutaneous manifestations of Acne vulgaris","volume":"61","author":"Luderschmidt","year":"1986","journal-title":"Z Hautkr"},{"key":"R4-20250920","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0190-9622(81)70068-9","article-title":"Squamous cell carcinoma arising in dissecting perifolliculitis of the scalp. A case report and review of secondary squamous cell carcinomas","volume":"4","author":"Curry","year":"1981","journal-title":"J Am Acad Dermatol"},{"key":"R5-20250920","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1600-0560.1997.tb01572.x","article-title":"Folliculotropic mycosis fungoides with large-cell transformation presenting as dissecting cellulitis of the scalp","volume":"24","author":"Gilliam","year":"1997","journal-title":"J Cutan Pathol"},{"key":"R6-20250920","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1001\/archderm.1962.01590030076010","article-title":"Perifolliculitis capitis abscedens et suffodiens. A report of six cases","volume":"85","author":"Moyer","year":"1962","journal-title":"Arch Dermatol"},{"key":"R7-20250920","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1001\/archderm.1992.01680200039004","article-title":"Perifolliculitis capitis abscedens et suffodiens. Resolution with combination therapy","volume":"128","author":"Shaffer","year":"1992","journal-title":"Arch Dermatol"},{"key":"R8-20250920","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1001\/archderm.1985.01660080082019","article-title":"Perifolliculitis capitis abscedens et suffodiens (Hoffman). Complete healing associated with oral zinc therapy","volume":"121","author":"Berne","year":"1985","journal-title":"Arch Dermatol"},{"key":"R9-20250920","first-page":"328","article-title":"Perifolliculitis capitis abscedens and suffidiens. Efficacy of isotretinoin","volume":"121","author":"Dubost-Brama","year":"1994","journal-title":"Ann Dermatol Venereol"},{"key":"R10-20250920","first-page":"195","article-title":"Dissecting cellulitis of the scalp treated with rifampicin and isotretinoin: case reports","volume":"82","author":"Georgala","year":"2008","journal-title":"Cutis"},{"key":"R11-20250920","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1111\/j.1468-3083.2005.01215.x","article-title":"Perifolliculitis capitis abscedens et suffodiens","volume":"19","author":"Ljubojevic","year":"2005","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"R12-20250920","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1001\/archderm.1956.01550030058005","article-title":"Perifolliculitis capitis abscedens et suffodiens; its successful treatment with x-ray epilation","volume":"73","author":"McMullan","year":"1956","journal-title":"AMA Arch Derm"},{"key":"R13-20250920","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/j.1524-4725.1989.tb03608.x","article-title":"Treatment of perifolliculitis capitis abscedens et suffodiens with the carbon dioxide laser","volume":"15","author":"Glass","year":"1989","journal-title":"J Dermatol Surg Oncol"},{"key":"R14-20250920","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2310\/7750.2007.00004","article-title":"Perifolliculitis capitis abscedens et suffodiens in an 18-year-old Aboriginal Canadian patient: case report and review of the literature","volume":"11","author":"Varshney","year":"2007","journal-title":"J Cutan Med Surg"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00076423-201156030-00016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:48:59Z","timestamp":1787838539000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00076423-201156030-00016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.4103\/0019-5154.82492","relation":{},"ISSN":["0019-5154","1998-3611"],"issn-type":[{"value":"0019-5154","type":"print"},{"value":"1998-3611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5]]},"assertion":[{"value":"2010-04-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-10-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}