{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:20:03Z","timestamp":1787847603219,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p>\n                    Klinefelter's syndrome is a sex chromosome abnormality with low androgen level. The varied manifestations of the mental symptoms in some of them, that are inexplicable based on their genotype alone, has fascinated the researchers. We present here a case of Klinefelter's syndrome having a karyotype of mos 47, XXY, and also inversion in 9\n                    <jats:sup>th<\/jats:sup>\n                    chromosome, with schizophrenia. Despite the view that inv 9 is a normal variant, it is still worthwhile to explore whether it has any role in the etiology of schizophrenia especially when it occurs with other genotypic aberrations that are suspected to have relevance to psychiatric disorders including the Klinefelter's syndrome.\n                  <\/jats:p>","DOI":"10.4103\/0019-5545.94655","type":"journal-article","created":{"date-parts":[[2012,4,3]],"date-time":"2012-04-03T09:35:22Z","timestamp":1333445722000},"page":"88-90","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Klinefelter's syndrome (mosaic) with chromosome 9 inv and schizophrenia"],"prefix":"10.4103","volume":"54","author":[{"given":"R.","family":"Ponnudurai","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Sumitha","sequence":"additional","affiliation":[{"name":"Department of Biomedical Science Technology and Research, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teena","family":"Koshy","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solomon S. D.","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Thiruvikraman","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjana","family":"Rani","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20260529","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0140-6736(59)91891-4","article-title":"The chromosomes in a patient showing both mongolism and the Klinefelter syndrome","volume":"1","author":"Ford","year":"1959","journal-title":"Lancet"},{"key":"R4-20260529","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0924-9338(97)83296-8","article-title":"The MINI international neuropsychiatric interview (MINI): A short diagnostic structural interview: Reliability and validity according to the CIDI","volume":"12","author":"Lecrubier","year":"1997","journal-title":"Eur Psychiatry"},{"key":"R6-20260529","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/0006-3223(93)90107-O","article-title":"Pericentric region of chromosome 9 is a possible candidate region for linkage study of schizophrenia","volume":"33","author":"Nanko","year":"1993","journal-title":"Biol Psychiatry"},{"key":"R7-20260529","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0920-9964(02)00504-2","article-title":"Chromosome aberrations in a schizophrenia population","volume":"65","author":"Demirhan","year":"2003","journal-title":"Schizophr Res"},{"key":"R8-20260529","first-page":"281","article-title":"Chromosome X aneuploidy in Brazilian schizophrenic patients","volume":"24","author":"De Moraes","year":"2010","journal-title":"In vivo"},{"key":"R9-20260529","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1093\/schbul\/20.3.495","article-title":"Schizophrenia and sex chromosome anomalies","volume":"20","author":"DeLisi","year":"1994","journal-title":"Schizophrenia Bull"},{"key":"R10-20260529","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1192\/bjp.bp.105.008961","article-title":"Klinefelter's syndrome (Karyotype 47,XXY) and schizophrenia- spectrum pathology","volume":"189","author":"Van Rijn","year":"2006","journal-title":"Brit J Psychiatry"}],"container-title":["Indian Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01363795-201254010-00019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:23:39Z","timestamp":1787844219000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01363795-201254010-00019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.4103\/0019-5545.94655","relation":{},"ISSN":["0019-5545","1998-3794"],"issn-type":[{"value":"0019-5545","type":"print"},{"value":"1998-3794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}