{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:34:44Z","timestamp":1786649684959,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Germ cell tumor (GCT) is relatively uncommon in intracranial locations. They constitute ~ 0.3-0.6% of intracranial neoplasms and encompass a wide pathologic range. The majority occurs in young adults and occupies the midline locations like pineal gland followed by suprasellar compartment. These tumors are rare in the cerebral hemisphere, basal ganglia, thalamus and ventricles. Neuroimaging studies cannot differentiate GCTs from other tumors, and therefore, the diagnosis usually requires histological confirmation. Germ cell tumors can be divided into major groups including germinomas and nongerminomatous GCTs (NGGCTs). Their proper identification as well as histopathological typing is important as treatment and prognosis vary greatly between different groups. Germinomas have a superior prognosis and are more radiosensitive as compared to non-germinomatous germ cell tumors. Standard management is still controversial. In this case series we are presenting three cases of intracranial germ cell tumors arising in two unusual locations, that is intraventricular and thalamic region. Apart from the clinical, radiological, histopathological and surgical details we also discuss the various aspects of intracranial germ cell tumors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0022-3859.105449","type":"journal-article","created":{"date-parts":[[2013,1,3]],"date-time":"2013-01-03T06:14:27Z","timestamp":1357193667000},"page":"286-289","source":"Crossref","is-referenced-by-count":4,"title":["Intracranial germ cell tumors at unusual locations"],"prefix":"10.4103","volume":"58","author":[{"given":"C","family":"Rana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Krishnani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-10-20240205","doi-asserted-by":"crossref","first-page":"446","DOI":"10.3171\/jns.1997.86.3.0446","article-title":"Primary intracranial germ cell tumors: A clinical analysis of 153 histologically verified cases","volume":"86","author":"Matsutani","year":"1997","journal-title":"J Neurosurg"},{"key":"R2-10-20240205","doi-asserted-by":"crossref","first-page":"2564","DOI":"10.1002\/(SICI)1097-0142(19961215)78:12<2564::AID-CNCR16>3.0.CO;2-U","article-title":"Histoligically confirmed pineal tumors and other germ cell tumors of the brain","volume":"78","author":"Schild","year":"1996","journal-title":"Cancer"},{"key":"R3-10-20240205","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s11060-010-0119-7","article-title":"Germinomas in the basal ganglia: Magnetic resonance imaging classification and the prognosis","volume":"99","author":"Phi","year":"2010","journal-title":"J Neurooncol"},{"key":"R6-10-20240205","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3171\/jns.2002.97.1.0177","article-title":"Diagnostic significance of soluble c-kit in the cerebrospinal fluid of patients with germ cell tumors","volume":"97","author":"Miyanohara","year":"2002","journal-title":"J Neurosurg"},{"key":"R7-10-20240205","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1634\/theoncologist.2008-0037","article-title":"Pediatric central nervous system germ cell tumors: A review","volume":"13","author":"Echevarr\u00eda","year":"2008","journal-title":"Oncologist"},{"key":"R8-10-20240205","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1002\/(SICI)1097-0142(19970201)79:3<558::AID-CNCR19>3.0.CO;2-2","article-title":"Spontaneous regression of primary intracranial germinoma. A case report","volume":"79","author":"Ide","year":"1997","journal-title":"Cancer"},{"key":"R9-10-20240205","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1200\/JCO.2002.20.3.857","article-title":"Induction chemotherapy followed by low-dose involved-field radiotherapy for intracranial germ cell tumors","volume":"20","author":"Aoyama","year":"2002","journal-title":"J Clin Oncol"},{"key":"R10-10-20240205","doi-asserted-by":"crossref","first-page":"56","DOI":"10.2302\/kjm.60.56","article-title":"Intracranial germ cell tumors: efficacy of neoadjuvant chemo-radiotherapy without surgical biopsy","volume":"60","author":"Takahashi","year":"2011","journal-title":"Keio J Med"}],"container-title":["Journal of Postgraduate Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00005257-201258040-00010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:57:03Z","timestamp":1786647423000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00005257-201258040-00010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.4103\/0022-3859.105449","relation":{},"ISSN":["0022-3859"],"issn-type":[{"value":"0022-3859","type":"print"}],"subject":[],"published":{"date-parts":[[2012]]}}}