{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:41:33Z","timestamp":1786653693805,"version":"build-2736575974"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Meningiomas are uncommon neoplasms in the pediatric age group and differ in various aspects from their adult counterparts. They account for 0.4-4.6% of all primary brain tumors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>To retrospectively analyze the clinicopathological and immunohistochemical features of pediatric meningiomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Meningiomas in patients under 18 years of age diagnosed between January 2001 to December 2011 were analyzed retrospectively. The hematoxylin and eosin stained sections and Ki 67 labelling index (LI) were reviewed for all the cases<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The pediatric meningiomas accounted for 1.52% of total meningiomas (15\/983). The mean age at presentation was 12 years with male to female ratio of 1.5:1. The presenting symptoms were headache, seizures, and motor deficits. The histology included 9 cases (60%) of atypical meningioma (WHO grade II) followed by 4 cases (26.67%) of WHO grade-I and 2 cases (13.33%) of anaplastic meningioma (WHO grade III). Five cases had a recurrence. Ki67 LI ranged from 0.5% to 1.5% in grade I, 0.5% to 15% in grade II and 13% to 24% in grade III meningiomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Meningiomas are rare in children and show a male preponderance. There was a higher incidence of atypical and anaplastic meningiomas in pediatric population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0022-3859.147035","type":"journal-article","created":{"date-parts":[[2014,12,15]],"date-time":"2014-12-15T07:14:10Z","timestamp":1418627650000},"page":"32-35","source":"Crossref","is-referenced-by-count":19,"title":["Pediatric meningiomas an aggressive subset"],"prefix":"10.4103","volume":"61","author":[{"given":"M","family":"Hui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MS","family":"Uppin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M Vijaya","family":"Saradhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BP","family":"Sahu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AK","family":"Purohit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Sundaram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-7-20240205","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0090-3019(84)90107-1","article-title":"Intracranial meningiomas in childhood","volume":"21","author":"Chan","year":"1984","journal-title":"Surg Neurol"},{"key":"R2-7-20240205","first-page":"21","article-title":"Intracranial meningiomas in children","volume":"5","author":"Yang","year":"2000","journal-title":"Chin J ClinNeurosurg"},{"key":"R3-7-20240205","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1212\/WNL.17.9.914","article-title":"Congenital meningioma","volume":"17","author":"Mendiratta","year":"1967","journal-title":"Neurology"},{"key":"R4-7-20240205","first-page":"61","article-title":"Meningiomas in children: A study of 18 cases","volume":"4","author":"Mehta","year":"2009","journal-title":"J PediatrNeurosci"},{"key":"R5-7-20240205","doi-asserted-by":"crossref","first-page":"204","DOI":"10.4103\/0028-3886.79140","article-title":"Meningiomas: Correlation of Ki67 with histological grade","volume":"59","author":"Babu","year":"2011","journal-title":"Neurol India"},{"key":"R6-7-20240205","first-page":"134","article-title":"Intracranial meningiomas in children","volume":"12","author":"Drake","year":"1986","journal-title":"PediatrNeurosci 1985"},{"key":"R7-7-20240205","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0090-3019(85)90030-8","article-title":"Antiestrogenic therapy of meningiomas - A pilot study","volume":"24","author":"Markwalder","year":"1985","journal-title":"Surg Neurol"},{"key":"R8-7-20240205","first-page":"112","article-title":"Clinical features and treatment of meningiomas in children: Report of 12 cases and literature review","volume":"44","author":"Liu","year":"2008","journal-title":"PediatrNeurosurg"},{"key":"R9-7-20240205","doi-asserted-by":"crossref","first-page":"447","DOI":"10.3171\/jns.1994.80.3.0447","article-title":"Intracranial meningiomas of the first two decades of life","volume":"80","author":"Germano","year":"1994","journal-title":"J Neurosurg"},{"key":"R10-7-20240205","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/S0022-3476(74)80011-9","article-title":"Meningiomas of childhood andadolescence","volume":"84","author":"Merten","year":"1974","journal-title":"J Pediatr"},{"key":"R11-7-20240205","first-page":"43","article-title":"Intracranial meningiomas of infancy, childhood and adolescence. Review of the literature and addition of 9 case reports","volume":"7","author":"Herz","year":"1980","journal-title":"Childs Brain"},{"key":"R12-7-20240205","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/BF00570253","article-title":"Pediatric cystic meningioma: Report of three cases","volume":"11","author":"Artico","year":"1995","journal-title":"Childs NervSyst"},{"key":"R13-7-20240205","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1002\/1097-0142(197510)36:4<1363::AID-CNCR2820360427>3.0.CO;2-Z","article-title":"Papillary meningioma: A malignant variant of meningioma","volume":"36","author":"Ludwin","year":"1975","journal-title":"Cancer"},{"key":"R14-7-20240205","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1093\/jnen\/60.10.994","article-title":"Aggressive phenotypic and genotypic features in pediatric and NF2-associated meningiomas: Aclinicopathologic study of 53 cases","volume":"60","author":"Perry","year":"2001","journal-title":"J Neuropathol ExpNeurol"},{"key":"R15-7-20240205","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1097\/00006123-200103000-00027","article-title":"MIB-1staining index of pediatric meningiomas","volume":"48","author":"Sandberg","year":"2001","journal-title":"Neurosurgery"}],"container-title":["Journal of Postgraduate Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00005257-201561010-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:41:03Z","timestamp":1786650063000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00005257-201561010-00007"}},"subtitle":["A clinicopathological and immunohistochemical study"],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.4103\/0022-3859.147035","relation":{},"ISSN":["0022-3859"],"issn-type":[{"value":"0022-3859","type":"print"}],"subject":[],"published":{"date-parts":[[2015]]}}}