{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:40:40Z","timestamp":1786653640911,"version":"build-2736575974"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal hyper inflammatory condition, if not recognized and treated in time. A high index of suspicion can help identify the condition early. This condition can occur in the primary or secondary form. Secondary HLH or hemophagocytic syndrome (HPS) secondary to infections is an important clinical entity especially in tropical world. In this article, we share our experience with this entity and make an attempt to explore literature about ravenous macrophages which occurs secondary to infections. It is a series of six cases of HLH secondary to infectious disease in our center in a coastal city in South India over last one year with follow up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0022-3859.150904","type":"journal-article","created":{"date-parts":[[2015,2,5]],"date-time":"2015-02-05T07:03:55Z","timestamp":1423119835000},"page":"112-115","source":"Crossref","is-referenced-by-count":11,"title":["Hemophagocytic lymphohistiocytosis secondary to infections"],"prefix":"10.4103","volume":"61","author":[{"given":"P","family":"Kodan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Chakrapani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Shetty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Pavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20240205","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.pcl.2012.03.002","article-title":"Making sense of the cytokine storm: A conceptual framework for understanding, diagnosing, and treating hemophagocytic syndromes","volume":"59","author":"Canna","year":"2012","journal-title":"Pediatr Clin North Am"},{"key":"R3-11-20240205","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1086\/323675","article-title":"The role of infections in primary hemophagocytic lymphohistiocytosis: A case series and review of the literature","volume":"33","author":"Sung","year":"2001","journal-title":"Clin Infect Dis"},{"key":"R5-11-20240205","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1016\/j.amjmed.2013.07.018","article-title":"Fifty, febrile, and fatigued: High ferritin as a clue in diagnosis","volume":"126","author":"Gorlitsky","year":"2013","journal-title":"Am J Med"},{"key":"R6-11-20240205","first-page":"481","article-title":"Hemophagocytic lymphohistiocytosis associated with dermatomyositis: A case report","volume":"77","author":"Thomas","year":"2013","journal-title":"Conn Med"},{"key":"R7-11-20240205","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.autrev.2014.01.058","article-title":"Adult-onset still's disease","volume":"13","author":"Gerfaud-Valentin","year":"2014","journal-title":"Autoimmune Rev"},{"key":"R11-11-20240205","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1002\/pbc.21423","article-title":"Highly elevated ferritin levels and the diagnosis of hemophagocytic lymphohistiocytosis","volume":"50","author":"Allen","year":"2008","journal-title":"Pediatr Blood Cancer"},{"key":"R12-11-20240205","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.jbspin.2011.10.015","article-title":"Hemophagocytic lymphohistiocytosis in adults: Diagnosis and treatment","volume":"79","author":"Larroche","year":"2012","journal-title":"Joint Bone Spine"},{"key":"R13-11-20240205","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1007\/s00134-008-1111-y","article-title":"62; C, Galicier L, Buyse S, Azoulay E. 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