{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:28:45Z","timestamp":1786649325910,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare condition characterized by the presence of diffuse thrombotic microthrombi and fibrocellular intimal proliferation in the pulmonary vasculature. Its development is linked to the presence of pulmonary tumor microemboli (PTM) and should be suspected in patients with unexplained dyspnea, especially in the presence of adenocarcinoma. PTTM presents in a similar fashion to respiratory disease such as pulmonary embolism, pulmonary hypertension or pneumonia and is usually only diagnosed post-mortem. We report a case of PTTM identified ante-mortem by bronchial biopsy in an 82-year-old woman presenting with a clinical picture of atypical pneumonia. Autopsy confirmed PTTM, from an unknown primary neoplasm.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0022-3859.48439","type":"journal-article","created":{"date-parts":[[2009,2,26]],"date-time":"2009-02-26T23:35:16Z","timestamp":1235691316000},"page":"38-40","source":"Crossref","is-referenced-by-count":14,"title":["Unusual presentation of pulmonary tumor thrombotic microangiopathy with no detectable primary tumor"],"prefix":"10.4103","volume":"55","author":[{"given":"N","family":"Seppala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Cala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Klebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-10-20240205","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1002\/1097-0142(19900801)66:3<587::AID-CNCR2820660330>3.0.CO;2-J","article-title":"Pulmonary tumor thrombotic microangiopathy with hypertenson","volume":"66","author":"Von Herbay","year":"1990","journal-title":"Cancer"},{"key":"R2-10-20240205","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S0140-6736(05)60721-0","article-title":"Cor pulmonale and tumour cell microemboli","volume":"352","author":"Sekizawa","year":"1998","journal-title":"Lancet"},{"key":"R3-10-20240205","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0002-9343(03)00305-X","article-title":"Pulmonary tumor embolism: A review of the literature","volume":"115","author":"Roberts","year":"2003","journal-title":"Am J Med"},{"key":"R4-10-20240205","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1440-1827.2007.02111.x","article-title":"Pulmonary tumor thrombotic microangiopathy resulting from metastatic signet ring cell carcinoma of the stomach","volume":"57","author":"Sakashita","year":"2007","journal-title":"Pathol Int"},{"key":"R5-10-20240205","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S1092-9134(00)90038-8","article-title":"Tumor-related thrombotic pulmonary microangiopathy: Review of pathologic findings and pathophysiologic mechanisms","volume":"4","author":"Pinckard","year":"2000","journal-title":"Ann Diagn Pathol"},{"key":"R6-10-20240205","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ijcard.2006.11.162","article-title":"Fatal Acute pulmonary hypertension caused by pulmonary tumour thrombotic microangiopathy","volume":"124","author":"Keenan","year":"2008","journal-title":"Int J Cardiol"},{"key":"R7-10-20240205","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1136\/jcp.56.11.866","article-title":"Pulmonary tumour microembolism clinically mimicking alveolitis","volume":"56","author":"Lo","year":"2003","journal-title":"J Clin Pathol"},{"key":"R8-10-20240205","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1046\/j.1440-1843.2000.00262.x","article-title":"A case of pulmonary tumour embolism mimicking miliary tuberculosis","volume":"5","author":"Chai","year":"2000","journal-title":"Respirology"},{"key":"R9-10-20240205","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3132\/pcrj.2007.00020","article-title":"Microscopic pulmonary neoplastic emboli: Report of a case with respiratory failure but normal imaging","volume":"16","author":"Chatkin","year":"2007","journal-title":"Prim Care Respir J"},{"key":"R10-10-20240205","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1742-1241.2007.01497.x","article-title":"Pulmonary hypertension and the serotonin hypothesis: Where are we now?","volume":"61","author":"MacLean","year":"2007","journal-title":"Int J Clin Pract"}],"container-title":["Journal of Postgraduate Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00005257-200955010-00010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:52:29Z","timestamp":1786647149000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00005257-200955010-00010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.4103\/0022-3859.48439","relation":{},"ISSN":["0022-3859"],"issn-type":[{"value":"0022-3859","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]}}}