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Diligent clinical evaluation and a battery of tests are required for making a definitive diagnosis. Newer advanced diagnostic techniques, such as diffusion-weighted magnetic resonance imaging (MRI), perfusion-weighted MRI, magnetic resonance spectroscopy, single-photon emission tomography and positron emission tomography may help in establishing the etiology. However, early brain biopsy is often needed because several of these diseases are potentially life-threatening.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0022-3859.70939","type":"journal-article","created":{"date-parts":[[2010,10,7]],"date-time":"2010-10-07T04:58:33Z","timestamp":1286427513000},"page":"307-316","source":"Crossref","is-referenced-by-count":77,"title":["Multiple ring-enhancing lesions of the brain"],"prefix":"10.4103","volume":"56","author":[{"given":"RK","family":"Garg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MK","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-18-20240205","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S1474-4422(06)70597-X","article-title":"Pitfalls in the diagnosis of brain tumours","volume":"5","author":"Omuro","year":"2006","journal-title":"Lancet Neurol"},{"key":"R2-18-20240205","doi-asserted-by":"crossref","first-page":"101","DOI":"10.5858\/133.1.101","article-title":"Intracranial lesions mimicking neoplasms","volume":"133","author":"Cunliffe","year":"2009","journal-title":"Arch Pathol Lab Med"},{"key":"R3-18-20240205","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1148\/rg.272065155","article-title":"Patterns of contrast enhancement in the brain and meninges","volume":"27","author":"Smirniotopoulos","year":"2007","journal-title":"Radiographics"},{"key":"R4-18-20240205","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.jns.2007.09.012","article-title":"Multiple ring enhancing brain lesions on computed tomography: an Indian perspective","volume":"266","author":"Garg","year":"2008","journal-title":"J Neurol Sci"},{"key":"R5-18-20240205","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s00234-005-0024-5","article-title":"Pattern of T2 hypointensity associated with ring-enhancing brain lesions can help to differentiate pathology","volume":"48","author":"Schwartz","year":"2006","journal-title":"Neuroradiology"},{"key":"R6-18-20240205","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s11940-008-0033-x","article-title":"Brain metastases","volume":"10","author":"Eichler","year":"2008","journal-title":"Curr Treat Options Neurol"},{"key":"R7-18-20240205","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1001\/archneur.1979.00500460064009","article-title":"Computerized tomography in intracranial metastases","volume":"36","author":"Weisberg","year":"1979","journal-title":"Arch Neurol"},{"key":"R8-18-20240205","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1227\/01.NEU.0000182774.54193.37","article-title":"Neuroimaging of Metastatic Brain Disease","volume":"57","author":"Young","year":"2005","journal-title":"Neurosurgery"},{"key":"R9-18-20240205","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1552-6569.2003.tb00185.x","article-title":"Brain CT and MRI findings in 100 consecutive patients with intracranial tuberculoma","volume":"13","author":"Wasay","year":"2003","journal-title":"J Neuroimaging"},{"key":"R10-18-20240205","first-page":"867","article-title":"Magnetization transfer MR imaging in CNS tuberculosis","volume":"20","author":"Gupta","year":"1999","journal-title":"Am J Neuroradiol"},{"key":"R11-18-20240205","first-page":"171","article-title":"Diagnostic criteria for neurocysticercosis: some modifications are needed for Indian patients","volume":"52","author":"Garg","year":"2004","journal-title":"Neurol India"},{"key":"R12-18-20240205","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1212\/WNL.57.2.177","article-title":"Proposed diagnostic criteria for neurocysticercosis","volume":"57","author":"Del Brutto","year":"2001","journal-title":"Neurology"},{"key":"R13-18-20240205","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1007\/s00701-003-0113-3","article-title":"Acute demyelination: diagnostic difficulties and the need for brain biopsy","volume":"145","author":"Maarouf","year":"2003","journal-title":"Acta Neurochir (Wien"},{"key":"R14-18-20240205","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1212\/WNL.54.7.1427","article-title":"Open-ring sign: highly specific for atypical brain demyelination","volume":"54","author":"Masdeu","year":"2000","journal-title":"Neurology"},{"key":"R15-18-20240205","first-page":"171","article-title":"Neuroimaging of AIDS. 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