{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:20:53Z","timestamp":1787847653790,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>We report a case of cerebral actinomycosis in a 62-year-old male who presented with right-sided weakness and focal convulsions. MRI scan showed a solid intra axial space occupying lesion in the left frontal lobe. Left parietal craniotomy with intra-operative USG guided aspiration and excision of the mass (containing necrotic material) was done. Actinomyces israelii was isolated from the aspirated material. Patient received ceftriaxone and clindamycin for 12 weeks. Physiotherapy and anti-epileptic drugs were continued. On subsequent follow-up visits, his power improved to 5\/5 in lower limb, 4\/5 in proximal upper limb, 2\/5 in distal upper limb. Actinomycosis can cause diverse clinical manifestations, and therefore clinical suspicion is key to diagnosis. Early diagnosis and treatment can lead to good treatment outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0028-3886.314572","type":"journal-article","created":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T01:30:50Z","timestamp":1619400650000},"page":"475-477","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["A Case of CNS Actinomycosis"],"prefix":"10.4103","volume":"69","author":[{"given":"Harshad S","family":"Limaye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anupa R A","family":"Hinduja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitusha","family":"Verma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradyumna J","family":"Oak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-50-20240907","doi-asserted-by":"crossref","first-page":"e362","DOI":"10.1016\/j.wneu.2018.04.205","article-title":"Central nervous system actinomycosis\u2014A clinicoradiologic and histopathologic analysis","volume":"116","author":"Ravindra","year":"2018","journal-title":"World Neurosurg"},{"key":"R2-50-20240907","first-page":"183","article-title":"Actinomycosis: Etiology, clinical features, diagnosis, treatment, and management","volume":"7","author":"Valour","year":"2014","journal-title":"Infect Drug Resist"},{"key":"R3-50-20240907","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1513\/pats.200907-077AL","article-title":"Bacteria that masquerade as fungi: Actinomycosis\/nocardia","volume":"7","author":"Sullivan","year":"2010","journal-title":"Proc Am Thorac Soc"},{"key":"R5-50-20240907","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3340\/jkns.2011.50.2.147","article-title":"Cerebral actinomycosis: Unusual clinical and radiological findings of an abscess","volume":"50","author":"Ham","year":"2011","journal-title":"J Korean Neurosurg Soc"},{"key":"R6-50-20240907","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1128\/CMR.00100-14","article-title":"Actinomyces and related organisms in human infections","volume":"28","author":"K\u00f6n\u00f6nen","year":"2015","journal-title":"Clin Microbiol Rev"},{"key":"R7-50-20240907","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1093\/clinids\/9.5.855","article-title":"Actinomycosis of the central nervous system","volume":"9","author":"Smego","year":"1987","journal-title":"Rev Infect Dis"},{"key":"R8-50-20240907","doi-asserted-by":"crossref","first-page":"d6099","DOI":"10.1136\/bmj.d6099","article-title":"Actinomycosis","volume":"343","author":"Wong","year":"2011","journal-title":"BMJ"},{"key":"R9-50-20240907","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.anaerobe.2014.05.015","article-title":"Antimicrobial susceptibility of clinical isolates of anaerobic bacteria in Ontario, 2010\u20132011","volume":"28","author":"Marchand-Austin","year":"2014","journal-title":"Anaerobe"},{"key":"R10-50-20240907","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/jac\/dki206","article-title":"Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents","volume":"56","author":"Smith","year":"2005","journal-title":"J Antimicrobial Chemotherapy"}],"container-title":["Neurology India"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.314572","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:26:35Z","timestamp":1787844395000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.314572"}},"subtitle":["Rarer than Rare!"],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/0028-3886.314572","relation":{},"ISSN":["0028-3886"],"issn-type":[{"value":"0028-3886","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]}}}