{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:23:53Z","timestamp":1787844233182,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Non-convulsive status epileptics (NCSE) is a common neurological emergency necessitating rapid assessment and management, but is often underdiagnosed as it lacks specific electroencephalographic features. The diagnostic value of periodic lateralized epileptiform discharges (PLEDs) in NCSE is still unclear. Herein, we reported a case with NCSE manifesting as PLEDs and coma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Report:<\/jats:title>\n                    <jats:p>A 62-year-old man presented with epileptic seizures. Based on clinical and radiological profiles, he was diagnosed with frontal hemorrhage, coma, and NCSE. An electroencephalogram (EEG) revealed PLEDs. A combined antiepileptic regimen was initiated and, over a follow-up period of 2 months, a favorable outcome was achieved.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>EEG may help identify potential NCSE in comatose patients, and PLEDs can be an atypical manifestation of NCSE, which can be effectively treated with antiepileptic drugs. The emphasis in NCSE is on early identification and individualized therapeutic regimens.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0028-3886.317237","type":"journal-article","created":{"date-parts":[[2021,5,30]],"date-time":"2021-05-30T03:14:08Z","timestamp":1622344448000},"page":"733-736","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Non-Convulsive Status Epileptics Presenting with Periodic Lateralized Epileptiform Discharges and Coma after Cerebral Hemorrhage"],"prefix":"10.4103","volume":"69","author":[{"given":"Zhuo","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaojia","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoyang","family":"Jing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyu","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihong","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-40-20240907","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1212\/WNL.55.9.1421-a","article-title":"Prevalence of nonconvulsive status epilepticus in comatose patients","volume":"55","author":"Towne","year":"2000","journal-title":"Neurology"},{"key":"R2-40-20240907","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.seizure.2008.06.013","article-title":"Non-convulsive status epilepticus; The rate of occurrence in a general hospital","volume":"18","author":"Alroughani","year":"2009","journal-title":"Seizure"},{"key":"R3-40-20240907","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.spen.2010.06.009","article-title":"Nonconvulsive status epilepticus and continuous spike and slow wave of sleep in children","volume":"17","author":"Akman","year":"2010","journal-title":"Semin Pediatr Neurol"},{"key":"R4-40-20240907","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0013-4694(96)95726-0","article-title":"Periodic lateralized epileptiform discharges (PLEDs) following stroke are associated with metabolic abnormalities","volume":"102","author":"Neufeld","year":"1997","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"R5-40-20240907","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1016\/S1388-2457(00)00466-1","article-title":"Multifocal periodic lateralized epileptiform discharges (PLEDs): EEG features and clinical correlations","volume":"111","author":"Lawn","year":"2000","journal-title":"Clin Neurophysiol"},{"key":"R6-40-20240907","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1111\/j.1528-1157.1998.tb01311.x","article-title":"Nonconvulsive status epilepticus in the critically ill elderly","volume":"39","author":"Litt","year":"1998","journal-title":"Epilepsia"},{"key":"R7-40-20240907","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1136\/postgradmedj-2015-133537","article-title":"Non-convulsive status epilepticus: A practical approach to diagnosis in confused older people","volume":"91","author":"Woodford","year":"2015","journal-title":"Postgrad Med J"}],"container-title":["Neurology India"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.317237","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:15:20Z","timestamp":1787843720000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.317237"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/0028-3886.317237","relation":{},"ISSN":["0028-3886"],"issn-type":[{"value":"0028-3886","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}