{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T10:29:02Z","timestamp":1788431342466,"version":"build-2803163510"},"reference-count":86,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:p>Frontotemporal dementia (FTD) is an entity that includes a group of neurodegenerative disease with symptoms predominantly pertaining to deficits in behavior, executive function (or) language. FTD is one of the most common type of dementia before 65 years of age and is one of the most underdiagnosed dementia as most often the symptoms overlap with psychiatric manifestations. Based on the clinical features, FTD is further subdivided into behavioral variant FTD (Bv-FTD) and primary progressive dementia (PPA). We searched PubMed, MEDLINE, and Google Scholar for articles about FTD disease published in English between January 1, 1975 till 2018. We used the search terms \u201cfrontotemporal dementia,\u201d \u201cFronto temporal dementia-motor neuron disease,\u201d \u201cdementia,\u201d \u201ccognition,\u201d \u201cbehavioral variant,\u201d and \u201cprimary progressive aphasia.<\/jats:p>","DOI":"10.4103\/0028-3886.329593","type":"journal-article","created":{"date-parts":[[2024,9,7]],"date-time":"2024-09-07T15:06:39Z","timestamp":1725721599000},"page":"1144-1152","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":27,"title":["Frontotemporal Dementia \u2013 Current Concepts"],"prefix":"10.4103","volume":"69","author":[{"given":"Goutham Kumar","family":"Puppala","sequence":"first","affiliation":[{"name":"Department of Neurology, Kasturba Hospital, Manipal, Udupi, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shankar Prasad","family":"Gorthi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kasturba Hospital, Manipal, Udupi, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Chandran","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kasturba Hospital, Manipal, Udupi, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gautham","family":"Gundabolu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kasturba Hospital, Manipal, Udupi, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,10,30]]},"reference":[{"key":"R1-20250925","doi-asserted-by":"crossref","first-page":"88","DOI":"10.2174\/1745017901309010088","article-title":"Epidemiology of early-onset dementia: A review of the literature","volume":"9","author":"Vieira","year":"2013","journal-title":"Clin Pract Epidemiol Ment Health"},{"key":"R2-20250925","first-page":"165","article-title":"Uber die Beziehungen der senilen Hirnatrophie zur Aphasie","volume":"17","author":"Pick","year":"1892","journal-title":"Prager Med Wochenschr"},{"key":"R3-20250925","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/BF02866241","article-title":"Uber eigenartige Krankheitsfalle der spateren Alters","volume":"4","author":"Alzheimer","year":"1911","journal-title":"Z Gesamte Neurol Psychiatr"},{"key":"R4-20250925","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/S1474-4422(08)70169-8","article-title":"Alzheimer's disease and vascular dementia in developing countries: Prevalence, management and risk factors","volume":"7","author":"Kalaria","year":"2008","journal-title":"Lancet Neurol"},{"key":"R6-20250925","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1016\/S0140-6736(05)67889-0","article-title":"Global prevalence of dementia: A Delphi consensus study","volume":"366","author":"Ferri","year":"2005","journal-title":"Lancet"},{"key":"R7-20250925","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1159\/000329862","article-title":"Subtypes of dementia: A study from a memory clinic in India","volume":"32","author":"Alladi","year":"2011","journal-title":"Dement Geriatr Cogn Disord"},{"key":"R8-20250925","first-page":"103","article-title":"Clinical profile of young onset dementia: A study from eastern India","volume":"13","author":"Nandi","year":"2008","journal-title":"Neurol Asia"},{"key":"R9-20250925","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/ana.91","article-title":"Primary progressive aphasia","volume":"49","author":"Mesulam","year":"2001","journal-title":"Ann Neurol"},{"key":"R10-20250925","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1136\/jnnp.51.3.353","article-title":"Dementia of frontal lobe type","volume":"51","author":"Neary","year":"1988","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"R11-20250925","first-page":"65","article-title":"Frontal lobe dementia of non-Alzheimer type","volume":"51","author":"Gustafson","year":"1990","journal-title":"Adv Neurol"},{"key":"R12-20250925","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00401-009-0612-2","article-title":"Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: An update","volume":"119","author":"Mackenzie","year":"2010","journal-title":"Acta Neuropathol"},{"key":"R13-20250925","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1001\/archneurol.2007.38","article-title":"Frontal paralimbic network atrophy in very mild behavioral Variant frontotemporal dementia","volume":"65","author":"Seeley","year":"2008","journal-title":"Arch Neurol"},{"key":"R14-20250925","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1093\/cercor\/bhr004","article-title":"Selective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia","volume":"22","author":"Kim","year":"2012","journal-title":"Cereb Corte\u00d7"},{"key":"R15-20250925","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s00401-011-0839-6","article-title":"Neuropathological background of phenotypical variability in frontotemporal dementia","volume":"122","author":"Josephs","year":"2011","journal-title":"Acta Neuropathol"},{"key":"R16-20250925","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s00401-012-1029-x","article-title":"The genetics and neuropathology of frontotemporal lobar degeneration","volume":"124","author":"Sieben","year":"2012","journal-title":"Acta Neuropathol"},{"key":"R17-20250925","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s00401-011-0845-8","article-title":"A harmonized classification system for FTLD-TDP pathology","volume":"122","author":"Mackenzie","year":"2011","journal-title":"Acta Neuropathol"},{"key":"R18-20250925","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1212\/WNL.0b013e318202038c","article-title":"TDP-43 subtypes are associated with distinct atrophy patterns in frontotemporal dementia","volume":"75","author":"Rohrer","year":"2010","journal-title":"Neurology"},{"key":"R19-20250925","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s00401-010-0765-z","article-title":"Pathological correlates of frontotemporal lobar degeneration in the elderly","volume":"121","author":"Baborie","year":"2011","journal-title":"Acta Neuropathol"},{"key":"R20-20250925","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/00002093-200210000-00001","article-title":"Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank","volume":"16","author":"Barker","year":"2002","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"R21-20250925","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s00401-010-0764-0","article-title":"Distinct pathological subtypes of FTLD-FUS","volume":"121","author":"Mackenzie","year":"2011","journal-title":"Acta Neuropathol"},{"key":"R22-20250925","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1212\/WNL.0b013e3181bf997a","article-title":"The heritability and genetics of Fronto temporal lobar degeneration","volume":"73","author":"Rohrer","year":"2009","journal-title":"Neurology"},{"key":"R23-20250925","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.neurol.2013.07.014","article-title":"Genetics of frontotemporal lobar degeneration: An up-date and diagnosis algorithm","volume":"169","author":"Le Ber","year":"2013","journal-title":"Rev Neurol (Paris)"},{"key":"R24-20250925","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1002\/humu.20785","article-title":"Granulin mutations associated with frontotemporal lobar degeneration and related disorders: An update","volume":"29","author":"Gijselinck","year":"2008","journal-title":"Hum Mutat"},{"key":"R25-20250925","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1007\/s12031-011-9569-4","article-title":"Structure, function, and mechanism of progranulin; the brain and beyond","volume":"45","author":"Toh","year":"2011","journal-title":"J Mol Neurosci"},{"key":"R26-20250925","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.neuron.2011.09.011","article-title":"Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS","volume":"72","author":"DeJesus-Hernandez","year":"2011","journal-title":"Neuron"},{"key":"R27-20250925","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.neuron.2011.09.010","article-title":"A hexanucleotide repeat expansion in C9ORF72is the cause of chromosome 9p21-linked ALS-FTD","volume":"72","author":"Renton","year":"2011","journal-title":"Neuron"},{"key":"R28-20250925","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1093\/brain\/awn061","article-title":"Atypical frontotemporal lobar degeneration with ubiquitin-positive, TDP-43-negative neuronal inclusions","volume":"131","author":"Mackenzie","year":"2008","journal-title":"Brain"},{"key":"R29-20250925","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1002\/humu.22319","article-title":"TARDBP and FUS mutations associated with amyotrophic lateral sclerosis: Summary and update","volume":"34","author":"Lattante","year":"2013","journal-title":"Hum Mutat"},{"key":"R30-20250925","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1007\/s00401-013-1192-8","article-title":"Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD\/ALS","volume":"126","author":"Gendron","year":"2013","journal-title":"Acta Neuropathol"},{"key":"R31-20250925","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1007\/s00401-013-1200-z","article-title":"C9orf72 frontotemporal lobar degeneration is characterised by frequent neuronal sense and antisense RNA foci","volume":"126","author":"Mizielinska","year":"2013","journal-title":"Acta Neuropathol"},{"key":"R32-20250925","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1212\/CON.0000000000000300","article-title":"Frontotemporal Dementias","volume":"22","author":"Finger","year":"2016","journal-title":"Continuum (Minneap Minn)"},{"key":"R34-20250925","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1212\/WNL.0b013e31821103e6","article-title":"Classification of primary progressive aphasia and its variants","volume":"76","author":"Gorno-Tempini","year":"2011","journal-title":"Neurology"},{"key":"R35-20250925","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1093\/brain\/awt163","article-title":"A novel frontal pathway underlies verbal fluency in primary progressive aphasia","volume":"136","author":"Catani","year":"2013","journal-title":"Brain"},{"key":"R36-20250925","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1093\/brain\/awt222","article-title":"Anterior temporal lobe degeneration produces widespread network-driven dysfunction","volume":"136","author":"Guo","year":"2013","journal-title":"Brain"},{"key":"R37-20250925","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.neurobiolaging.2007.05.014","article-title":"Atrophy progression in semantic dementia with asymmetric temporal involvement: A tensor-based morphometry study","volume":"30","author":"Brambati","year":"2009","journal-title":"Neurobiol Aging"},{"key":"R38-20250925","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/ana.10825","article-title":"Cognition and anatomy in three variants of primary progressive aphasia","volume":"55","author":"Gorno-Tempini","year":"2004","journal-title":"Ann Neurol"},{"key":"R39-20250925","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jns.2012.04.002","article-title":"The frontotemporal dementias in a tertiary referral center: Classification and demographic characteristics in a series of 232 cases","volume":"318","author":"Ioannidis","year":"2012","journal-title":"J Neurol Sci"},{"key":"R40-20250925","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1212\/01.WNL.0000091868.28557.B8","article-title":"Left\/right asymmetry of atrophy in Semantic dementia: Behavioral-cognitive implications","volume":"61","author":"Thompson","year":"2003","journal-title":"Neurology"},{"key":"R41-20250925","doi-asserted-by":"crossref","first-page":"2945","DOI":"10.1093\/brain\/awl254","article-title":"Structural anatomy of empathy in neurodegenerative disease","volume":"129","author":"Rankin","year":"2006","journal-title":"Brain"},{"key":"R42-20250925","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1136\/jnnp-2014-309120","article-title":"Differentiating between right-lateralised semantic dementia and behavioural-variant frontotemporal dementia: An examination of clinical characteristics and emotion processing","volume":"86","author":"Kamminga","year":"2015","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"R43-20250925","doi-asserted-by":"crossref","first-page":"2582","DOI":"10.1093\/brain\/awr195","article-title":"Motor neuron dysfunction in Frontotemporal dementia","volume":"134","author":"Burrell","year":"2011","journal-title":"Brain"},{"key":"R44-20250925","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1016\/S0140-6736(15)00461-4","article-title":"Frontotemporal dementia","volume":"386","author":"Bang","year":"2015","journal-title":"Lancet"},{"key":"R45-20250925","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1080\/17470218.2014.980280","article-title":"Past, present, and prospects: Reflections 40 years on from the selective impairment of semantic memory (Warrington, 1975)","volume":"69","author":"McCarthy","year":"2016","journal-title":"Q J Exp Psychol (Hove)"},{"issue":"Suppl 1","key":"R46-20250925","first-page":"S65","article-title":"Frontotemporal dementia: An updated overview","volume":"51","author":"Mohandas","year":"2009","journal-title":"Indian J Psychiatry"},{"key":"R47-20250925","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1212\/WNL.47.1.1","article-title":"Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): Report of the NINDS-SPSP international workshop","volume":"47","author":"Litvan","year":"1996","journal-title":"Neurology"},{"key":"R48-20250925","doi-asserted-by":"crossref","first-page":"1214.e7","DOI":"10.1016\/j.neurobiolaging.2013.12.004","article-title":"C9ORF72 hexanucleotide repeat expansion is a rare cause of schizophrenia","volume":"35","author":"Galimberti","year":"2014","journal-title":"Neurobiol Aging"},{"key":"R49-20250925","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1111\/bdi.12169","article-title":"C9ORF72 hexanucleotide repeat expansion as a rare cause of bipolar disorder","volume":"16","author":"Galimberti","year":"2014","journal-title":"Bipolar Disord"},{"key":"R50-20250925","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.biopsych.2013.01.031","article-title":"Autosomal dominant frontotemporal lobar degeneration due to the C9ORF72 hexanucleotide repeat expansion: Late-onset psychotic clinical presentation","volume":"74","author":"Galimberti","year":"2013","journal-title":"Biol Psychiatry"},{"key":"R51-20250925","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1093\/brain\/awr179","article-title":"Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia","volume":"134","author":"Rascovsky","year":"2011","journal-title":"Brain"},{"key":"R52-20250925","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1067\/mcp.2001.113989","article-title":"Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework","volume":"69","year":"2001","journal-title":"Clin Pharmacol Ther"},{"issue":"Suppl 1","key":"R53-20250925","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/jnc.13656","article-title":"Advances in neuroimaging in frontotemporal dementia","volume":"138","author":"Gordon","year":"2016","journal-title":"J Neurochem"},{"key":"R54-20250925","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3109\/09540261.2013.778822","article-title":"Neuroimaging in frontotemporal dementia","volume":"25","author":"Rohrer","year":"2013","journal-title":"Int Rev Psychiatry"},{"key":"R55-20250925","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1093\/brain\/aww005","article-title":"MRI visual rating scales in the diagnosis of dementia: Evaluation in 184 post-mortem confirmed cases","volume":"139","author":"Harper","year":"2016","journal-title":"Brain"},{"key":"R56-20250925","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1093\/brain\/awp232","article-title":"Distinct anatomical subtypes of the behavioural variant of frontotemporal dementia: A cluster analysis study","volume":"132","author":"Whitwell","year":"2009","journal-title":"Brain"},{"key":"R57-20250925","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1093\/brain\/aws001","article-title":"Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics","volume":"135","author":"Whitwell","year":"2012","journal-title":"Brain"},{"key":"R58-20250925","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1212\/WNL.0b013e31821ccd3c","article-title":"Progression of language decline and cortical atrophy in subtypes of primary Progressive aphasia","volume":"76","author":"Rogalski","year":"2011","journal-title":"Neurology"},{"key":"R59-20250925","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/j.neuroimage.2009.12.088","article-title":"Distinct profiles of brain atrophy in frontotemporal lobar degeneration caused by progranulin and tau mutations","volume":"53","author":"Rohrer","year":"2010","journal-title":"Neuroimage"},{"key":"R60-20250925","first-page":"103","article-title":"Cerebral hypometabolism and grey matter density in MAPT intron 10+3 mutation carriers","volume":"3","author":"Deters","year":"2014","journal-title":"Am J Neurodegener Dis"},{"key":"R61-20250925","doi-asserted-by":"crossref","first-page":"2602","DOI":"10.1002\/hbm.22794","article-title":"MRI signatures of the frontotemporal lobar degeneration continuum","volume":"36","author":"Agosta","year":"2015","journal-title":"Hum Brain Mapp"},{"key":"R62-20250925","doi-asserted-by":"crossref","first-page":"4163","DOI":"10.1002\/hbm.22468","article-title":"Profiles of white matter tract pathology in frontotemporal dementia","volume":"35","author":"Mahoney","year":"2014","journal-title":"Hum Brain Mapp"},{"key":"R63-20250925","doi-asserted-by":"crossref","first-page":"3547","DOI":"10.1002\/hbm.22420","article-title":"Longitudinal white matter changes in frontotemporal dementia subtypes","volume":"35","author":"Lam","year":"2014","journal-title":"Hum Brain Mapp"},{"key":"R64-20250925","doi-asserted-by":"crossref","first-page":"857","DOI":"10.4103\/0028-3886.73745","article-title":"Tc-99m ethylcysteinate dimer SPECT in the differential diagnosis of dementias","volume":"58","author":"Tripathi","year":"2010","journal-title":"Neurol India"},{"key":"R65-20250925","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S1474-4422(09)70299-6","article-title":"Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade","volume":"9","author":"Jack","year":"2010","journal-title":"Lancet Neurol"},{"key":"R66-20250925","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1007\/s00259-016-3335-3","article-title":"Mapping brain morphological and functional conversion patterns in predementia late-onset bvFTD","volume":"43","author":"Morbelli","year":"2016","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"R67-20250925","doi-asserted-by":"crossref","first-page":"3050","DOI":"10.1007\/s00330-015-3696-1","article-title":"Cerebral perfusion and glucose metabolism in Alzheimer's disease and frontotemporal dementia: Two sides of the same coin?","volume":"25","author":"Verfaillie","year":"2015","journal-title":"Eur Radiol"},{"key":"R68-20250925","doi-asserted-by":"crossref","first-page":"e18111","DOI":"10.1371\/journal.pone.0018111","article-title":"Combined evaluation of FDG-PET and MRI improves detection and differentiation of dementia","volume":"6","author":"Dukart","year":"2011","journal-title":"PLoS One"},{"key":"R69-20250925","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.3233\/JAD-160285","article-title":"Diagnostic Accuracy of MRI and Additional [18F] FDG-PET for Behavioral Variant Frontotemporal Dementia in Patients with Late Onset Behavioral Changes","volume":"53","author":"Vijverberg","year":"2016","journal-title":"J Alzheimers Dis"},{"key":"R70-20250925","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/s11682-016-9521-x","article-title":"Pathophysiology of the behavioral variant of frontotemporal lobar degeneration: A study combining MRI and FDG-PET","volume":"11","author":"Buhour","year":"2017","journal-title":"Brain Imaging Behav"},{"key":"R71-20250925","doi-asserted-by":"crossref","first-page":"183","DOI":"10.3233\/JAD-160682","article-title":"The Role of single-subject brain metabolic patterns in the early differential diagnosis of primary progressive aphasias and in prediction of progression to dementia","volume":"55","author":"Cerami","year":"2017","journal-title":"J Alzheimers Dis"},{"key":"R72-20250925","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4103\/0972-3919.90255","article-title":"Spectrum of neurocognitive dysfunction in Indian population on FDG PET\/CT imaging","volume":"26","author":"Sharma","year":"2011","journal-title":"Indian J Nucl Med"},{"key":"R73-20250925","doi-asserted-by":"crossref","first-page":"96","DOI":"10.4103\/0972-3919.90261","article-title":"FDG-PET findings in fronto-temporal dementia: A case report and review of literature","volume":"26","author":"Harisankar","year":"2011","journal-title":"Indian J Nucl Med"},{"key":"R74-20250925","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/mrm.25197","article-title":"Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia","volume":"73","author":"Alsop","year":"2015","journal-title":"Magn Reson Med"},{"key":"R75-20250925","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.nicl.2016.08.001","article-title":"Cerebral blood flow in presymptomatic MAPT and GRN mutation carriers: A Longitudinal arterial spin labeling study","volume":"12","author":"Dopper","year":"2016","journal-title":"Neuroimage Clin"},{"key":"R76-20250925","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1007\/s00330-015-3789-x","article-title":"Early-stage differentiation between presenile Alzheimer's disease and frontotemporal dementia using arterial spin labeling MRI","volume":"26","author":"Steketee","year":"2016","journal-title":"Eur Radiol"},{"key":"R77-20250925","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1212\/01.wnl.0000238163.71349.78","article-title":"Hypoperfusion in frontotemporal dementia and Alzheimer disease by arterial spin labeling MRI","volume":"67","author":"Du","year":"2006","journal-title":"Neurology"},{"key":"R78-20250925","doi-asserted-by":"crossref","first-page":"461","DOI":"10.3389\/fnhum.2013.00461","article-title":"GroupICA dual regression analysis of resting state networks in a behavioral variant of frontotemporal dementia","volume":"7","author":"Rytty","year":"2013","journal-title":"Front Hum Neurosci"},{"key":"R79-20250925","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1016\/j.neurobiolaging.2014.05.017","article-title":"Disrupted brain connectome in semantic variant of primary progressive aphasia","volume":"35","author":"Agosta","year":"2014","journal-title":"Neurobiol Aging"},{"key":"R80-20250925","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1016\/j.neurobiolaging.2011.10.031","article-title":"Granulin mutation drives brain damage and reorganization from Preclinical to symptomatic FTLD","volume":"33","author":"Borroni","year":"2012","journal-title":"Neurobiol Aging"},{"key":"R81-20250925","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.3174\/ajnr.A3695","article-title":"PET approaches for diagnosis of dementia","volume":"35","author":"Ishii","year":"2014","journal-title":"AJNR Am J Neuroradiol"},{"key":"R82-20250925","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1093\/brain\/aww163","article-title":"18F-AV-1451 tau PET imaging correlates strongly with tau neuropathology in MAPT mutation carriers","volume":"139","author":"Smith","year":"2016","journal-title":"Brain"},{"key":"R83-20250925","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.brainresbull.2016.09.002","article-title":"Specialized roles of neurofilament proteins in synapses: Relevance to neuropsychiatric disorders","volume":"126","author":"Yuan","year":"2016","journal-title":"Brain Res Bull"},{"key":"R84-20250925","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1002\/acn3.325","article-title":"Neurofilament light chain: A biomarker for genetic frontotemporal dementia","volume":"3","author":"Meeter","year":"2016","journal-title":"Ann Clin Transl Neurol"},{"key":"R85-20250925","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1083\/jcb.200712039","article-title":"Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival","volume":"181","author":"Van Damme","year":"2008","journal-title":"J Cell Biol"},{"key":"R86-20250925","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1093\/brain\/awn352","article-title":"Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members","volume":"132","author":"Finch","year":"2009","journal-title":"Brain"},{"key":"R87-20250925","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1159\/000333132","article-title":"Optimal plasma progranulin cutoff value for predicting null progranulin mutations in neurodegenerative diseases: A multicenter Italian study","volume":"9","author":"Ghidoni","year":"2012","journal-title":"Neurodegener Dis"},{"key":"R88-20250925","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1159\/000447738","article-title":"Progranulin levels in plasma and cerebrospinal fluid in granulin mutation carriers","volume":"6","author":"Meeter","year":"2016","journal-title":"Dement Geriatr Cogn Dis Extra"}],"container-title":["Neurology India"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.329593","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:40:29Z","timestamp":1787067629000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.329593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":86,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/0028-3886.329593","relation":{},"ISSN":["0028-3886","1998-4022"],"issn-type":[{"value":"0028-3886","type":"print"},{"value":"1998-4022","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"2018-07-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-03","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}