{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T03:14:58Z","timestamp":1788578098066,"version":"build-2803163510"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>Although gelastic seizures (GSs) with extrahypothalamic epileptogenic zones such as the frontal, temporal, or parietal lobes have been previously reported, reports of GSs arising from the occipital region are rare. Herein, we describe the seizure propagation pattern of mirthless GSs confirmed by intracranial EEG in a case of MRI-negative occipital lobe epilepsy. In this patient, EEG onset was localized to the right occipital lobe while the onset of laughter coincided with seizure propagation to the right basal temporal region. This finding suggested that the symptomatogenic area for GSs in the occipital lobe may reside in the basal temporal region, and the basal temporal region may play a role in laughing behaviors. This case demonstrated that an elaborate analysis of electroclinical features combined with imaging findings may lead to successful seizure localization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0028-3886.333525","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T01:47:50Z","timestamp":1640656070000},"page":"1813-1816","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["MRI-Negative Occipital Lobe Epilepsy Presenting as Gelastic Seizures"],"prefix":"10.4103","volume":"69","author":[{"given":"Lingli","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-63-20240907","doi-asserted-by":"crossref","first-page":"364","DOI":"10.5152\/npa.2016.12586","article-title":"Epileptic seizures with mirthful laughter","volume":"53","author":"Zeydan","year":"2016","journal-title":"Noro Psikiyatri Ars"},{"key":"R2-63-20240907","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.yebeh.2014.03.024","article-title":"Different localizations underlying cortical gelastic epilepsy: Case series and review of literature","volume":"35","author":"Tran","year":"2014","journal-title":"Epilepsy Behav"},{"key":"R3-63-20240907","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.0013-9580.2005.47704.x","article-title":"Ictal smile lateralizes to the right hemisphere in childhood epilepsy","volume":"46","author":"Fogarasi","year":"2005","journal-title":"Epilepsia"},{"key":"R4-63-20240907","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.3389\/fneur.2018.01013","article-title":"Application of MRI Post-processing in presurgical evaluation of non-lesional cingulate epilepsy","volume":"9","author":"Wang","year":"2018","journal-title":"Front Neurol [Internet"},{"key":"R5-63-20240907","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.1093\/brain\/awr238","article-title":"Imaging the seizure onset zone with stereo-electroencephalography","volume":"134","author":"David","year":"2011","journal-title":"Brain"},{"key":"R6-63-20240907","doi-asserted-by":"crossref","first-page":"872645","DOI":"10.1155\/2015\/872645","article-title":"The classical pathways of occipital lobe epileptic propagation revised in the light of white matter eissection","volume":"2015","author":"Latini","year":"2015","journal-title":"Behav Neurol"},{"key":"R7-63-20240907","first-page":"115","article-title":"Occipital seizures presenting with bilateral visual loss","volume":"51","author":"Hadjikoutis","year":"2003","journal-title":"Neurol India"},{"key":"R8-63-20240907","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1684\/j.1950-6945.2003.tb00014.x","article-title":"From hypothalamic hamartoma to cortex: What can be learnt from depth recordings and stimulation?","volume":"5","author":"Kahane","year":"2004","journal-title":"Epileptic Disord"},{"key":"R9-63-20240907","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1111\/j.1528-1167.2008.01810.x","article-title":"Functional brain mapping of ictal activity in gelastic epilepsy associated with hypothalamic hamartoma: A case report","volume":"50","author":"Leal","year":"2009","journal-title":"Epilepsia"},{"key":"R10-63-20240907","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.neuropsychologia.2016.07.001","article-title":"Smile and laughter elicited by electrical stimulation of the frontal operculum","volume":"89","author":"Caruana","year":"2016","journal-title":"Neuropsychologia"},{"key":"R11-63-20240907","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1093\/brain\/116.4.757","article-title":"Mirth, laughter and gelastic seizures","volume":"116","author":"Arroyo","year":"1993","journal-title":"Brain"},{"key":"R12-63-20240907","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.cortex.2014.11.008","article-title":"Neural correlates of mirth and laughter: A direct electrical cortical stimulation study","volume":"66","author":"Yamao","year":"2015","journal-title":"Cortex"},{"key":"R13-63-20240907","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1684\/j.1950-6945.2005.tb00114.x","article-title":"Gelastic seizures due to right temporal cortical dysplasia","volume":"7","author":"Dericioglu","year":"2005","journal-title":"Epileptic Disord"}],"container-title":["Neurology India"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.333525","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:51:51Z","timestamp":1787755911000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.333525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/0028-3886.333525","relation":{},"ISSN":["0028-3886"],"issn-type":[{"value":"0028-3886","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]}}}