{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T21:20:20Z","timestamp":1790025620423,"version":"4.0.1"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Dengue is a common viral infection worldwide, though its neurological manifestations are infrequent (2%\u201311% in recent years) and can be varied as the Dengue virus per se is a non-neurotropic virus. Neurological manifestations of Dengue usually result from multisystem dysfunction which may be secondary to vascular leak or it can be due to direct virus invasion (dengue encephalitis) or an immunological phenomenon which is triggered by dengue infection (demyelinating disorders). Here we present two cases of dengue fever associated demyelinating disorders in two pediatric patients aptly depicting the two spectra of the disease. One of them is a case of fatal acute hemorrhagic leukoencephalopathy (AHLE) in a 3-year-old girl, that developed severe neurological sequelae while the other one is a case of an Acute disseminated Encephalomyelitis (ADEM) in a 3-year-old boy who had recovered with timely immunomodulatory therapy and appropriate management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0028-3886.349659","type":"journal-article","created":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T03:55:57Z","timestamp":1692849357000},"page":"1244-1246","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Dengue Associated Demyelinating Disorders \u2013 A Report of 2 Cases"],"prefix":"10.4103","volume":"70","author":[{"given":"Mimi","family":"Ganguly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabhas P","family":"Giri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mausumi","family":"Mukherjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harshita","family":"Jagwani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arundhati","family":"Banerjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-75-20241013","doi-asserted-by":"crossref","first-page":"S70","DOI":"10.12980\/APJTB.4.2014C1006","article-title":"Dengue encephalitis-A rare manifestation of dengue fever","volume":"4","author":"Madi","year":"2014","journal-title":"Asian Pac J Trop Biomed"},{"key":"R2-75-20241013","doi-asserted-by":"crossref","first-page":"581","DOI":"10.4103\/0028-3886.68654","article-title":"Neurological complications of dengue infection","volume":"58","author":"Murthy","year":"2010","journal-title":"Neurol India"},{"key":"R3-75-20241013","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.4081\/ni.2012.e15","article-title":"Dengue: A new challenge for neurology","volume":"4","author":"Puccioni-Sohler","year":"2012","journal-title":"Neurol Int"},{"key":"R4-75-20241013","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1212\/WNL.0000000000002877","article-title":"Consensus definitions for pediatric MS and other demyelinating disorders in childhood","volume":"87","author":"Tardieu","year":"2016","journal-title":"Neurology"},{"key":"R5-75-20241013","doi-asserted-by":"crossref","first-page":"e0005715","DOI":"10.1371\/journal.pntd.0005715","article-title":"Post-dengue acute disseminated encephalomyelitis: A case report and meta-analysis","volume":"11","author":"Kamel","year":"2017","journal-title":"PLoS Negl Trop Dis"},{"key":"R7-75-20241013","doi-asserted-by":"crossref","first-page":"52","DOI":"10.4103\/0972-9062.213331","article-title":"Acute disseminated encephalomyelitis and dengue fever: Comment","volume":"49","author":"Zaki","year":"2012","journal-title":"J Vector Borne Dis"},{"key":"R8-75-20241013","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jocn.2017.05.033","article-title":"Acute disseminated encephalomyelitis in dengue viral infection","volume":"43","author":"Wan Sulaiman","year":"2017","journal-title":"J Clin Neurosci"}],"container-title":["Neurology India"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.349659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:30:00Z","timestamp":1786725000000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.349659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/0028-3886.349659","relation":{},"ISSN":["0028-3886"],"issn-type":[{"value":"0028-3886","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}