{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:37:37Z","timestamp":1787071057725,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Near-infrared spectroscopy (NIRS) is known to determine the adequacy of regional cerebral oxygen supply. NIRS values during anesthetic induction depends upon various factors such as anesthetic agents, inspired oxygen fraction, blood carbon dioxide levels and systemic blood pressure. Also high intracranial pressure (ICP) can lead to reduced NIRS values, secondary to increased cerebral vascular resistance induced decrease in cerebral blood flow. However optimal hyperventilation instituted as a bridge to definitive ICP management is difficult to ascertain as hypocapnia due to poorly titrated hyperventilation can potentially worsen ICP. Here we describe a novel application of NIRS-guided hyperventilation during anesthesia induction in a brain tumor patient with raised ICP features and impending uncal herniation as suggested by computed tomography (CT) scan, with ipsilateral baseline reduced NIRS values. These ipsilateral NIRS values further reduced significantly during anesthesia induction even before profound bradycardia occurred, which promptly improved to baseline following hyperventilation.<\/jats:p>","DOI":"10.4103\/0028-3886.355096","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T00:36:16Z","timestamp":1664152576000},"page":"1665-1667","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Near-Infrared Spectroscopy\u2013Guided Hyperventilation for Transient Intracranial Pressure Control during Anesthesia Induction in a Patient with Impending Uncal Herniation"],"prefix":"10.4103","volume":"70","author":[{"given":"Salini","family":"Varma","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Neuro Anesthesia Division, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranganatha","family":"Praveen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Neuro Anesthesia Division, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay P.","family":"Hrishi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Neuro Anesthesia Division, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manikandan","family":"Sethuraman","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Neuro Anesthesia Division, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, 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India"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.355096","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:40:52Z","timestamp":1787067652000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.355096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/0028-3886.355096","relation":{},"ISSN":["0028-3886","1998-4022"],"issn-type":[{"value":"0028-3886","type":"print"},{"value":"1998-4022","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"2021-12-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-13","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}