{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:35:55Z","timestamp":1787841355727,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Paroxysmal sympathetic hyper-activity (PSH) is a syndrome characterized by excessive activity of the sympathetic nervous system. The cerebrovascular flow dynamics during the episodes of paroxysmal hyper-activity has also not been clearly examined in the literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case History:<\/jats:title>\n                    <jats:p>A 12-year-old boy with operated exophytic brain stem pilocytic astrocytoma was diagnosed with paroxysmal sympathetic hyper-activity. The trans-cranial Doppler flow characteristics of the bilateral middle cerebral artery and anterior cerebral artery are described in this report.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The diagnosis of PSH requires an index of suspicion on the part of the clinician. The episodes of sympathetic hyper-activity are associated with significant changes in physiologic parameters in the patients including changes in cerebrovascular flow dynamics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0028-3886.355139","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T00:36:16Z","timestamp":1664152576000},"page":"1625-1628","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Trans-cranial Doppler Flow Characteristics of a Child with Paroxysmal Sympathetic Hyper-activity: A Preliminary Report"],"prefix":"10.4103","volume":"70","author":[{"given":"Debajyoti","family":"Datta","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Orissa, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vipin","family":"Chandran","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Orissa, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Orissa, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabi Narayan","family":"Sahu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Orissa, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,8,30]]},"reference":[{"key":"R1-20250921","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1089\/neu.2013.3301","article-title":"Paroxysmal sympathetic hyperactivity after acquired brain injury: Consensus on conceptual definition, nomenclature, and diagnostic criteria","volume":"31","author":"Baguley","year":"2014","journal-title":"J Neurotrauma"},{"key":"R2-20250921","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1055\/s-0040-1713845","article-title":"Paroxysmal sympathetic hyperactivity","volume":"40","author":"Scott","year":"2020","journal-title":"Semin Neurol"},{"key":"R3-20250921","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3389\/fneur.2020.00081","article-title":"Identification and management of paroxysmal sympathetic hyperactivity after traumatic brain injury","volume":"11","author":"Zheng","year":"2020","journal-title":"Front Neurol"},{"key":"R4-20250921","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1080\/02699052.2018.1482002","article-title":"Incidence of paroxysmal sympathetic hyperactivity following traumatic brain injury using assessment tools","volume":"32","author":"Samuel","year":"2018","journal-title":"Brain Inj"},{"key":"R5-20250921","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1007\/s00701-016-2934-x","article-title":"Paroxysmal sympathetic hyperactivity in severe traumatic brain injury","volume":"158","author":"Mathew","year":"2016","journal-title":"Acta neurochir (Wien)"},{"key":"R6-20250921","doi-asserted-by":"crossref","first-page":"254","DOI":"10.4103\/ijmpo.ijmpo_93_18","article-title":"Paroxysmal sympathetic hyperactivity\u2013An under-recognized entity in pediatric brain tumors: Case report and review of literature","volume":"41","author":"Krishnan","year":"2020","journal-title":"Indian J Med Paediatr Oncol"},{"key":"R7-20250921","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1186\/s40064-016-1898-x","article-title":"Paroxysmal sympathetic hyperactivity in brainstem-compressing huge benign tumors: Clinical experiences and literature review","volume":"5","author":"Lee","year":"2016","journal-title":"Springerplus"},{"key":"R8-20250921","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13089-017-0077-9","article-title":"Point-of-care transcranial Doppler by intensivists","volume":"9","author":"Lau","year":"2017","journal-title":"Crit Ultrasound J"},{"key":"R9-20250921","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.surneu.2003.12.007","article-title":"Transcranial Doppler sonography pulsatility index (PI) reflects intracranial pressure (ICP)","volume":"62","author":"Bellner","year":"2004","journal-title":"Surg Neurol"},{"key":"R10-20250921","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/bja\/aet122","article-title":"Sympathetic regulation of cerebral blood flow in humans: A review","volume":"111","author":"ter Laan","year":"2013","journal-title":"Br J Anaesth"}],"container-title":["Neurology India"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.355139","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:51:24Z","timestamp":1787838684000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.355139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/0028-3886.355139","relation":{},"ISSN":["0028-3886","1998-4022"],"issn-type":[{"value":"0028-3886","type":"print"},{"value":"1998-4022","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"2022-01-12","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}