{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:27:28Z","timestamp":1786728448825,"version":"build-2736575974"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Objective:<\/jats:title>\n                    <jats:p>In our study, we aimed to evaluate the sleep disturbances of patients diagnosed with restless legs syndrome (RLS) regarding their mental health according to the severity of the disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>The study included 166 patients diagnosed with RLS and 161 healthy controls in the same age interval as patients. Sleep disturbances of patients were defined with the \u201cpersonal information form\u201d (PIF) prepared by the researchers, while the mental health status of patients was defined with the \u201cBrief Symptom Inventory\u201d (BSI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      All RLS patients had an increase in BSI subscale points, with a positive correlation to disease severity, and subscale points were significantly higher than the control group (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.05). Those with the \u201cfrequent waking\u201d problem had higher BSI subscale points compared to those without the problem (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt;0.01 or 0.001). Those with \u201cwaking with respiratory distress,\u201d \u201cdaytime sleepiness,\u201d \u201cvery early waking,\u201d and \u201csleep disorder\u201d problems had statistically significantly high BSI subscale points for all subscales, apart from hostility, compared to those without these problems (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt;0.01 or 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>It is considered that assessment of sleep disturbances causing disrupted quality of life and mood disorders is beneficial for the treatment of patients with RLS. Our study data appears to be related to the result that sleep disturbances and mental health disruptions might be associated with the disease severity among RLS patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0028-3886.383850","type":"journal-article","created":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T04:21:33Z","timestamp":1692850893000},"page":"693-698","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Assessment of Sleep Disturbances on Mental Health in Patients with Restless Legs Syndrome"],"prefix":"10.4103","volume":"71","author":[{"given":"H\u00fclya","family":"Olgun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamer","family":"Yazar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berna B","family":"\u00c7akmak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeliz K","family":"Ar\u0131c\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-12-20240907","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/j.jagp.2016.04.003","article-title":"Restless legs syndrome and depression: Effect mediation by disturbed sleep and periodic limb movements","volume":"24","author":"Koo","year":"2016","journal-title":"Am J Geriatr Psychiatry"},{"key":"R2-12-20240907","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.sleep.2019.02.022","article-title":"Serum C-reactive protein\/albumin ratio and restless legs syndrome","volume":"58","author":"Yazar","year":"2019","journal-title":"Sleep Med"},{"key":"R3-12-20240907","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/j.jocn.2014.01.007","article-title":"Olanzapine-induced restless legs syndrome","volume":"21","author":"Zhao","year":"2014","journal-title":"J Clin Neurosci"},{"key":"R4-12-20240907","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.sleep.2014.03.025","article-title":"Restless legs syndrome\/Willis-Ekbom disease diagnostic criteria: Updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria--history, rationale, description, and significance","volume":"15","author":"Allen","year":"2014","journal-title":"Sleep Med"},{"key":"R5-12-20240907","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1093\/ndt\/gfh654","article-title":"Restless legs syndrome, insomnia and quality of life in patients on maintenance dialysis","volume":"20","author":"Mucsi","year":"2005","journal-title":"Nephrol Dial Transplant"},{"key":"R6-12-20240907","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1111\/j.1440-1819.2008.01825.x","article-title":"Restless legs syndrome and its relationship with insomnia symptoms and daytime distress: Epidemiological survey in Sweden","volume":"62","author":"Broman","year":"2008","journal-title":"Psychiatry Clin Neurosci"},{"key":"R7-12-20240907","doi-asserted-by":"crossref","first-page":"5","DOI":"10.2337\/diaspect.29.1.5","article-title":"Physiology of sleep","volume":"29","author":"Carley","year":"2016","journal-title":"Diabetes Spectr"},{"key":"R8-12-20240907","first-page":"241","article-title":"Sleep disorders: Classification and treatment","volume":"27","author":"Keskin","year":"2018","journal-title":"Arch Med Rev J"},{"key":"R9-12-20240907","first-page":"553","article-title":"Sleep deprivation: Impact on cognitive performance","volume":"3","author":"Alhola","year":"2007","journal-title":"Neuropsychiatr Dis Treat"},{"key":"R10-12-20240907","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.sleep.2018.10.008","article-title":"Insomnia symptoms and short sleep duration predict trajectory of mental health symptoms","volume":"54","author":"Biddle","year":"2019","journal-title":"Sleep Med"},{"key":"R11-12-20240907","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1378\/chest.08-1834","article-title":"Update on sleep and psychiatric disorders","volume":"135","author":"Sateia","year":"2009","journal-title":"Chest"},{"key":"R12-12-20240907","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0022-3956(97)00002-2","article-title":"Prevalence of DSM-IV diagnostic criteria of insomnia: Distinguishing insomnia related to mental disorders from sleep disorders","volume":"31","author":"Ohayon","year":"1997","journal-title":"J Psychiatr Res"},{"key":"R13-12-20240907","doi-asserted-by":"crossref","first-page":"S395","DOI":"10.1002\/mds.21665","article-title":"Clinical significance of RLS","volume":"22","author":"Hening","year":"2007","journal-title":"Mov Disord"},{"key":"R14-12-20240907","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.jsmc.2015.05.009","article-title":"Restless legs syndrome and psychiatric disorders","volume":"10","author":"Mackie","year":"2015","journal-title":"Sleep Med Clin"},{"key":"R15-12-20240907","doi-asserted-by":"crossref","first-page":"505","DOI":"10.2147\/nedt.2006.2.4.505","article-title":"The biopsychosocial effects of restless legs syndrome (RLS)","volume":"2","author":"Becker","year":"2006","journal-title":"Neuropsychiatr Dis Treat"},{"key":"R16-12-20240907","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.2147\/NDT.S174552","article-title":"Investigation of alexithymia and levels of anxiety and depression among patients with restless legs syndrome","volume":"14","author":"Yilmaz","year":"2018","journal-title":"Neuropsychiatr Dis Treat"},{"key":"R17-12-20240907","doi-asserted-by":"crossref","first-page":"513","DOI":"10.2147\/nedt.2006.2.4.513","article-title":"Effects of restless legs syndrome (RLS) on sleep","volume":"2","author":"Bogan","year":"2006","journal-title":"Neuropsychiatr Dis Treat"},{"key":"R19-12-20240907","first-page":"44","article-title":"A study of the Brief Symptom Inventory in Turkish Youth","volume":"9","author":"\u015eahin","year":"1994","journal-title":"T\u00fcrk Psikoloji Dergisi"},{"key":"R20-12-20240907","first-page":"205","article-title":"Assessment of mental health of carers according to patient stage of idiopathic Parkinson's disease","volume":"71","author":"Yazar","year":"2018","journal-title":"Ideggyogy Sz"},{"key":"R21-12-20240907","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1007\/s10072-018-3293-6","article-title":"Assessment of the mental health of carers according to the stage of patients with diagnosis of Alzheimer-type dementia","volume":"39","author":"Yazar","year":"2018","journal-title":"Neurol Sci"},{"key":"R22-12-20240907","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S1389-9457(02)00258-7","article-title":"Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome","volume":"4","author":"Walters","year":"2003","journal-title":"Sleep Med"},{"key":"R23-12-20240907","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1378\/chest.14-0970","article-title":"International classification of sleep disorders-third edition: Highlights and modifications","volume":"146","author":"Sateia","year":"2014","journal-title":"Chest"},{"key":"R25-12-20240907","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1176\/appi.neuropsych.15030055","article-title":"Psychiatric comorbidities in restless legs syndrome","volume":"28","author":"Kallweit","year":"2016","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"R26-12-20240907","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1111\/j.1468-1331.2007.01966.x","article-title":"Low RLS prevalence and awareness in central Greece: An epidemiological survey","volume":"14","author":"Hadjigeorgiou","year":"2007","journal-title":"Eur J Neurol"},{"key":"R27-12-20240907","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.sleep.2018.03.011","article-title":"The bidirectional relationship between sleep duration and depression in community-dwelling middle-aged and elderly individuals: Evidence from a longitudinal study","volume":"52","author":"Sun","year":"2018","journal-title":"Sleep Med"},{"key":"R28-12-20240907","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s00415-005-0604-7","article-title":"\u201cAnxietas tibiarum\u201d. Depression and anxiety disorders in patients with restless legs syndrome","volume":"252","author":"Winkelmann","year":"2005","journal-title":"J Neurol"},{"key":"R29-12-20240907","doi-asserted-by":"crossref","first-page":"887","DOI":"10.4306\/pi.2017.14.6.887","article-title":"Individuals with restless legs syndrome tend to have severe depressive symptoms: Findings from a community-based cohort study","volume":"14","author":"Cho","year":"2017","journal-title":"Psychiatry Investig"},{"key":"R30-12-20240907","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1176\/jnp.2008.20.1.101","article-title":"Restless legs syndrome is associated with DSM-IV major depressive disorder and panic disorder in the community","volume":"20","author":"Lee","year":"2008","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"R31-12-20240907","first-page":"1069","article-title":"Restless legs syndrome in a community sample of Korean adults: Prevalence, impact on quality of life, and association with DSM-IV psychiatric disorders","volume":"32","author":"Cho","year":"2009","journal-title":"Sleep"},{"key":"R32-12-20240907","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.sleep.2019.01.029","article-title":"Sleep mediates the association between adolescent screen time and depressive symptoms","volume":"57","author":"Li","year":"2019","journal-title":"Sleep Med"},{"key":"R33-12-20240907","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.sleep.2017.07.016","article-title":"Relapse insomnia increases greater risk of anxiety and depression: Evidence from a population-based 4-year cohort study","volume":"38","author":"Chen","year":"2017","journal-title":"Sleep Med"},{"key":"R34-12-20240907","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1212\/WNL.0000000000003388","article-title":"Practice guideline summary: Treatment of restless legs syndrome in adults: Report of the guideline development, dissemination, and implementation subcommittee of the American Academy of Neurology","volume":"87","author":"Winkelman","year":"2016","journal-title":"Neurology"},{"key":"R35-12-20240907","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1185\/03007995.2014.918029","article-title":"Diagnosis, comorbidities, and management of restless legs syndrome","volume":"30","author":"Becker","year":"2014","journal-title":"Curr Med Res Opin"},{"key":"R36-12-20240907","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/1477-7525-9-73","article-title":"Psychological distress of patients suffering from restless legs syndrome: A cross-sectional study","volume":"9","author":"Scholz","year":"2011","journal-title":"Health Qual Life Outcomes"},{"key":"R37-12-20240907","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1007\/s11325-013-0800-0","article-title":"Psychosomatic symptom profiles in patients with restless legs syndrome","volume":"17","author":"Kim","year":"2013","journal-title":"Sleep Breath"},{"key":"R38-12-20240907","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/j.mcna.2014.06.009","article-title":"Psychiatric disorders and sleep \u0131ssues","volume":"98","author":"Sutton","year":"2014","journal-title":"Medical Clin North Am"}],"container-title":["Neurology India"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.383850","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:27:11Z","timestamp":1786724831000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0028-3886.383850"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/0028-3886.383850","relation":{},"ISSN":["0028-3886"],"issn-type":[{"value":"0028-3886","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]}}}