{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:03:39Z","timestamp":1787169819644,"version":"build-2736575974"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Acute stroke is an important cause of morbidity and mortality. Myocardial injury is an important complication of acute cerebrovascular events. Neurogenic stress cardiomyopathy (NSC) is a condition of acute myocardial systolic dysfunction that can be observed after acute cerebrovascular events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>In this study, we aimed to investigate the relationship between myocardial function assessed by two-dimensional speckle-tracking echocardiography and National Institutes of Health Stroke Scale (NIHSS) score in patients with acute ischemic stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This cross-sectional study screened 97 patients (males, 42; females, 55; 65 \u00b1 16 years) with acute ischemic stroke. Around 17 patients were excluded and 80 patients were studied. Patients were divided into two groups based on the calculated NIHSS score (Group 1, NIHSS score &lt;16; Group 2, NIHSS score \u226516). Demographic, clinical, and laboratory data for all patients were collected. Cardiac function was evaluated by two-dimensional speckle tracking echocardiography within 48 h of admission to the neurology care unit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      There were no significant differences in the demographic parameters of patients. The absolute value of global longitudinal systolic strain (GLS) was significantly higher in Group 1 patients than in Group 2 patients (21.4 \u00b1 2.2 vs 15.9 \u00b1 2.7,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0281). We found that thirteen patients (22%) had normal LVEF and abnormal LV GLS in Group 1 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.036). Eight patients (36%) had normal LVEF and abnormal LV GLS in Group 2 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.042). E\/e', QT on ECG, and serum troponin levels were significantly higher in Group 2 patients than in Group 1 patients (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Our results suggest that GLS is associated with stroke severity on admission in patients with acute ischemic stroke. GLS is an indicator of myocardial deformation with a different from LVEF. GLS can detect early myocardial dysfunction despite preserved LVEF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0028-3886.388123","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T07:01:15Z","timestamp":1697612475000},"page":"933-939","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Assessment of Myocardial Function by Speckle Tracking Echocardiography in Patients with Acute Ischemic Stroke"],"prefix":"10.4103","volume":"71","author":[{"given":"Unal","family":"Ozturk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onder","family":"Ozturk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20240907","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1097\/HJH.0000000000001095","article-title":"Left ventricular ejection 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