{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:17:49Z","timestamp":1787847469138,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:p>\n                    Agranulocytosis is a rare complication of levamisole. We report a 22-year-old female who developed agranulocytosis due to levamisole. The patient initially presented with salmonellosis and agranulocytosis, and then she recovered with treatment. However, 2 months after discharge, she again presented with tonsillitis and agranulocytosis. This time the family revealed that she had been taking levamisole. Though\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    infection is a recognized cause of agranulocytosis, any patient presenting with repeated agranulocytosis after an initial recovery should make the clinician suspect another cause, especially drug-induced. A case of\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    infection where levamisole was an unsuspecting cause of agranulocytosis has not been described in indexed literature. Recurrent agranulocytosis due to repeated exposure to levamisole has also not been described.\n                  <\/jats:p>","DOI":"10.4103\/0253-7613.165177","type":"journal-article","created":{"date-parts":[[2015,9,16]],"date-time":"2015-09-16T06:44:00Z","timestamp":1442385840000},"page":"565-566","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["A case of recurrent agranulocytosis due to levamisole"],"prefix":"10.4103","volume":"47","author":[{"given":"Abraham M.","family":"Ittyachen","sequence":"first","affiliation":[{"name":"Department of Medicine, Malankara Orthodox Syrian Church Medical College, Kolenchery, Ernakulam District, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohan B.","family":"Jose","sequence":"additional","affiliation":[{"name":"Department of Medicine, Malankara Orthodox Syrian Church Medical College, Kolenchery, Ernakulam District, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jobin R.","family":"Benjamin","sequence":"additional","affiliation":[{"name":"Department of Medicine, Malankara Orthodox Syrian Church Medical College, Kolenchery, Ernakulam District, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20260528","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/MOH.0b013e32834da9ef","article-title":"Agranulocytosis and other consequences due to use of illicit cocaine contaminated with levamisole","volume":"19","author":"Buchanan","year":"2012","journal-title":"Curr Opin Hematol"},{"key":"R2-20260528","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1136\/ewjm.172.4.248","article-title":"Severe neutropenia: A diagnostic approach","volume":"172","author":"Munshi","year":"2000","journal-title":"West J Med"},{"key":"R3-20260528","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1038\/2091084a0","article-title":"Tetramisole (R 8299), a new, potent broad spectrum anthelmintic","volume":"209","author":"Thienpont","year":"1966","journal-title":"Nature"},{"key":"R4-20260528","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1007\/s002800050576","article-title":"A phase I study of 5-fluorouracil, leucovorin and levamisole","volume":"39","author":"Cleary","year":"1997","journal-title":"Cancer Chemother Pharmacol"},{"key":"R5-20260528","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1023\/A:1014214122167","article-title":"Efficacy of albendazole and levamisole against gastrointestinal nematodes of sheep and goats in Morogoro, Tanzania","volume":"34","author":"Keyyu","year":"2002","journal-title":"Trop Anim Health Prod"},{"key":"R6-20260528","first-page":"151","article-title":"Drug-induced agranulocytosis in Salmonella infection","volume":"34","author":"Ovchinnikov","year":"1971","journal-title":"Sov Med"},{"key":"R7-20260528","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/clpt.1981.154","article-title":"A method for estimating the probability of adverse drug reactions","volume":"30","author":"Naranjo","year":"1981","journal-title":"Clin Pharmacol Ther"}],"container-title":["Indian Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01363791-201547050-00020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:19:25Z","timestamp":1787843965000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01363791-201547050-00020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.4103\/0253-7613.165177","relation":{},"ISSN":["0253-7613","1998-3751"],"issn-type":[{"value":"0253-7613","type":"print"},{"value":"1998-3751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"2015-03-29","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-08-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}