{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T10:01:15Z","timestamp":1789725675172,"version":"4.0.1"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Pharmacol"],"published-print":{"date-parts":[[2016]]},"DOI":"10.4103\/0253-7613.186189","type":"journal-article","created":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T01:25:14Z","timestamp":1471483514000},"page":"424","source":"Crossref","is-referenced-by-count":13,"title":["Effect of nitrergic system on colonic motility in a rat model of irritable bowel syndrome"],"prefix":"10.4103","volume":"48","author":[{"given":"TijenKaya","family":"Temiz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omer","family":"Demir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma","family":"Simsek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YusufCem","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selen","family":"Bahceci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baris","family":"Karadas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asli","family":"Celik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gokhan","family":"Koyluoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0253-7613.186189-1","first-page":"1480","volume-title":"Functional bowel disorders","author":"Longstreth","year":"2006","journal-title":"Gastroenterology"},{"key":"key-10.4103\/0253-7613.186189-2","first-page":"1499","volume-title":"Colonic motility abnormality in patients with irritable bowel syndrome exhibiting abdominal pain and diarrhea","author":"Chey","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"key-10.4103\/0253-7613.186189-3","first-page":"725","volume-title":"Colonic tone and motility in patients with irritable bowel syndrome","author":"Vassallo","year":"1992","journal-title":"Mayo Clin Proc"},{"key":"key-10.4103\/0253-7613.186189-4","first-page":"18","volume-title":"A tutorial on the diffusibility and reactivity of free nitric oxide","author":"Lancaster","year":"1997","journal-title":"Nitric Oxide"},{"key":"key-10.4103\/0253-7613.186189-5","first-page":"903","volume-title":"Nitric oxide in gastrointestinal health and disease","author":"Shah","year":"2004","journal-title":"Gastroenterology"},{"key":"key-10.4103\/0253-7613.186189-6","first-page":"223","volume-title":"Neuronal nitric oxide synthase: Structure, subcellular localization, regulation, and clinical implications","author":"Zhou","year":"2009","journal-title":"Nitric Oxide"},{"key":"key-10.4103\/0253-7613.186189-7","first-page":"529","volume-title":"Targeting nitric oxide in the gastrointestinal tract","author":"Dijkstra","year":"2004","journal-title":"Curr Opin Investig Drugs"},{"key":"key-10.4103\/0253-7613.186189-8","first-page":"666","volume-title":"Role of neuronal nitric oxide synthase in colonic distension-induced hyperalgesia in distal colon of neonatal maternal separated male rats","author":"Tjong","year":"2011","journal-title":"Neurogastroenterol Motil"},{"key":"key-10.4103\/0253-7613.186189-9","first-page":"237","volume-title":"Increase in neurokinin-1 receptor-mediated colonic motor response in a rat model of irritable bowel syndrome","author":"La","year":"2005","journal-title":"World J Gastroenterol"},{"key":"key-10.4103\/0253-7613.186189-10","first-page":"777","volume-title":"Rectal mucosal nitric oxide in differentiation of inflammatory bowel disease and irritable bowel syndrome","author":"Reinders","year":"2005","journal-title":"Clin Gastroenterol Hepatol"},{"key":"key-10.4103\/0253-7613.186189-11","first-page":"27","volume-title":"The urinary 5-hydroxyindole acetic acid and plasma nitric oxide levels in irritable bowel syndrome: A preliminary study","author":"Yazar","year":"2005","journal-title":"Scott Med J"},{"key":"key-10.4103\/0253-7613.186189-12","first-page":"948","volume-title":"Effect of the 5-HT4 receptor and serotonin transporter on visceral hypersensitivity in rats","author":"Yan","year":"2012","journal-title":"Braz J Med Biol Res"},{"key":"key-10.4103\/0253-7613.186189-13","first-page":"1771","volume-title":"Rectal distention testing in patients with irritable bowel syndrome: Sensitivity, specificity, and predictive values of pain sensory thresholds","author":"Bouin","year":"2002","journal-title":"Gastroenterology"},{"key":"key-10.4103\/0253-7613.186189-14","first-page":"120","volume-title":"Asian motility studies in irritable bowel syndrome","author":"Lee","year":"2010","journal-title":"J Neurogastroenterol Motil"},{"key":"key-10.4103\/0253-7613.186189-15","first-page":"672","volume-title":"Antinociceptive effect of chronic lithium on visceral hypersensitivity in a rat model of diarrhea-predominant irritable bowel syndrome: The role of nitric oxide pathway","author":"Shamshiri","year":"2009","journal-title":"J Gastroenterol Hepatol"},{"key":"key-10.4103\/0253-7613.186189-16","first-page":"221","volume-title":"New insight into the functioning of nitric oxide-receptive guanylyl cyclase: Physiological and pharmacological implications","author":"Garthwaite","year":"2010","journal-title":"Mol Cell Biochem"},{"key":"key-10.4103\/0253-7613.186189-17","first-page":"G275","volume-title":"Nitrergic regulation of colonic transit in rats","author":"Mizuta","year":"1999","journal-title":"Am J Physiol"},{"key":"key-10.4103\/0253-7613.186189-18","first-page":"132","volume-title":"The spontaneous mechanical activity of the circular smooth muscle of the rabbit colon in vitro","author":"Benabdallah","year":"2008","journal-title":"Pharmacol Res"},{"key":"key-10.4103\/0253-7613.186189-19","first-page":"89","volume-title":"Effect of change in an inhibitory neurotransmitter of the myenteric plexus on the pathogenetic mechanism of irritable bowel syndrome subgroups in rat models","author":"Xu","year":"2006","journal-title":"Chin J Dig Dis"},{"key":"key-10.4103\/0253-7613.186189-20","first-page":"521","volume-title":"The role of nitric oxide and L-type calcium channel blocker in the contractility of rabbit ileum in vitro","author":"Ragy","year":"2012","journal-title":"J Physiol Biochem"},{"key":"key-10.4103\/0253-7613.186189-21","first-page":"393","volume-title":"Plasma nitrate concentration in infective gastroenteritis and inflammatory bowel disease","author":"Dykhuizen","year":"1996","journal-title":"Gut"},{"key":"key-10.4103\/0253-7613.186189-22","first-page":"980","volume-title":"The involvement of nitric oxide synthase neurons in enteric neuropathies","author":"Rivera","year":"2011","journal-title":"Neurogastroenterol Motil"},{"key":"key-10.4103\/0253-7613.186189-23","first-page":"485","volume-title":"Protective effect of S-nitroso-N-acetyl-penicillamine in endotoxin-induced acute intestinal damage in the rat","author":"Boughton-Smith","year":"1990","journal-title":"Eur J Pharmacol"}],"container-title":["Indian Journal of Pharmacology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T14:44:25Z","timestamp":1786632265000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0253-7613.186189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016]]}},"alternative-id":["186189"],"URL":"https:\/\/doi.org\/10.4103\/0253-7613.186189","relation":{},"ISSN":["0253-7613"],"issn-type":[{"value":"0253-7613","type":"print"}],"subject":[],"published":{"date-parts":[[2016]]}}}