{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:26:04Z","timestamp":1787772364958,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>Acute generalized exanthematous pustulosis (AGEP) is an uncommon and self-limiting skin rash commonly caused by drugs and is characterized by the acute onset of fever, pustulosis, and neutrophilia from 4 to 10 days after the drug intake. We describe a case of AGEP in a 61-year-old woman that was hospitalized for the acute onset of fever, erythroderma, and pustulosis. Clinical history revealed that she had been treating a bacterial inguinal intertrigo for 4 days with ciprofloxacin 500 mg tablets twice daily and desloratadine 5 mg tablet once daily. To the best of our knowledge, this is the third reported case of AGEP caused by ciprofloxacin, supporting two other previous reports.<\/jats:p>","DOI":"10.4103\/0253-7613.201014","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T15:04:50Z","timestamp":1716476690000},"page":"119-120","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Ciprofloxacin induced acute generallised exanthematous pustulosis"],"prefix":"10.4103","volume":"49","author":[{"given":"Caterina","family":"Foti","sequence":"first","affiliation":[{"name":"Dermatological Clinic, Department of Biomedical Science and Human Oncology, University of Bari, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Romita","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Biomedical Science and Human Oncology, University of Bari, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Zanframundo","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Biomedical Science and Human Oncology, University of Bari, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Mastrolonardo","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Unit of Dermatology, University of Foggia, Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianni","family":"Angelini","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Biomedical Science and Human Oncology, University of Bari, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianfranco","family":"Calogiuri","sequence":"additional","affiliation":[{"name":"IV Department of Pneumology, A. Galateo Hospital, San Cesario di Lecce, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eustacchio","family":"Nettis","sequence":"additional","affiliation":[{"name":"Unit of Allergology and Immunology, University of Bari, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Bonamonte","sequence":"additional","affiliation":[{"name":"Dermatological Clinic, Department of Biomedical Science and Human Oncology, University of Bari, Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20260528","doi-asserted-by":"crossref","first-page":"422","DOI":"10.4103\/0019-5154.160529","article-title":"Acute generalized exanthematous pustulosis due to insect bites?","volume":"60","author":"Bhat","year":"2015","journal-title":"Indian J Dermatol"},{"issue":"Suppl 4","key":"R2-20260528","first-page":"6","article-title":"Toxic pustuloderma \u2013 A new entity?","volume":"77","author":"Staughton","year":"1984","journal-title":"J R Soc Med"},{"key":"R3-20260528","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1034\/j.1600-0560.2001.028003113.x","article-title":"Acute generalized exanthematous pustulosis (AGEP) \u2013 A clinical reaction pattern","volume":"28","author":"Sidoroff","year":"2001","journal-title":"J Cutan Pathol"},{"key":"R4-20260528","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1093\/cid\/ciu126","article-title":"Severe cutaneous adverse reactions related to systemic antibiotics","volume":"58","author":"Lin","year":"2014","journal-title":"Clin Infect Dis"},{"key":"R5-20260528","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1111\/j.1365-2133.2007.08156.x","article-title":"Risk factors for acute generalized exanthematous pustulosis (AGEP)-results of a multinational case-control study (EuroSCAR)","volume":"157","author":"Sidoroff","year":"2007","journal-title":"Br J Dermatol"},{"key":"R6-20260528","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1111\/j.1365-4632.2009.04115.x","article-title":"Photoinduced acute exanthematous pustulosis caused by ciprofloxacin and sunlight exposure","volume":"48","author":"Knoell","year":"2009","journal-title":"Int J Dermatol"},{"key":"R7-20260528","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1159\/000087024","article-title":"Ciprofloxacin-induced acute generalized exanthematous pustulosis mimicking bullous drug eruption confirmed by a positive patch test","volume":"211","author":"Hausermann","year":"2005","journal-title":"Dermatology"}],"container-title":["Indian Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01363791-201749010-00023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:41:23Z","timestamp":1787769683000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01363791-201749010-00023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.4103\/0253-7613.201014","relation":{},"ISSN":["0253-7613","1998-3751"],"issn-type":[{"value":"0253-7613","type":"print"},{"value":"1998-3751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"2016-05-30","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-12-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}