{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T18:46:42Z","timestamp":1773773202943,"version":"3.50.1"},"reference-count":29,"publisher":"King Faisal Specialist Hospital and Research Centre","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Saudi Medicine"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.4103\/0256-4947.65255","type":"journal-article","created":{"date-parts":[[2010,7,8]],"date-time":"2010-07-08T08:49:21Z","timestamp":1278578961000},"page":"278-283","source":"Crossref","is-referenced-by-count":18,"title":["Cardiovascular disease markers in women with polycystic ovary syndrome with emphasis on asymmetric dimethylarginine and homocysteine"],"prefix":"10.5144","volume":"30","author":[{"given":"Ahmed M.","family":"Mohamadin","sequence":"first","affiliation":[{"name":"From the Department of Obstetrics and Gynecology, Clinical Biochemistry, College of Medicine, Taibah University, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fawzia A.","family":"Habib","sequence":"additional","affiliation":[{"name":"From the Department of Obstetrics and Gynecology, Clinical Biochemistry, College of Medicine, Taibah University, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulrahman A.","family":"Al-Saggaf","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Clinical Biochemistry, College of Medicine, Taibah University, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3134","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"583","DOI":"10.2217\/17455057.4.6.583","article-title":"Role of androgen excess on metabolic aberrations and cardiovascular risk in women with polycystic ovary syndrome","volume":"4","author":"Christakou CD","year":"2008","journal-title":"Womens Health (Lond Engl)"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.atherosclerosis.2008.09.010","article-title":"Polycystic ovary syndrome is associated with severe platelet and endothelial dysfunction in both obese and lean subjects","volume":"204","author":"Rajendran S","year":"2009","journal-title":".Atherosclerosis"},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1093\/humrep\/den239","article-title":"Clinical and biochemical characteristics of polycystic ovary syndrome in Korean women","volume":"23","author":"Chae SJ","year":"2008","journal-title":"Hum Reprod"},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.numecd.2008.05.004","article-title":"Insulin resistance and polycystic ovary syndrome","volume":"18","author":"Galluzzo A","year":"2008","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"e_1_3_2_6_2","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1161\/01.CIR.103.10.1410","article-title":"Polycystic ovary syndrome is associated with endothelial dysfunction","volume":"103","author":"Paradisi G","year":"2001","journal-title":"Circulation"},{"key":"e_1_3_2_7_2","doi-asserted-by":"crossref","first-page":"987","DOI":"10.2459\/JCM.0b013e32830b58d4","article-title":"Cardiovascular risk in women with polycystic ovary syndrome","volume":"9","author":"Giallauria F","year":"2008","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"e_1_3_2_8_2","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1042\/CS20080218","article-title":"A comprehensive assessment of endothelial function in overweight women with and without polycystic ovary syndrome","volume":"116","author":"Moran LJ","year":"2009","journal-title":"Clin Sci (Lond)"},{"key":"e_1_3_2_9_2","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1177\/1358836X0501000106","article-title":"Insulin resistance: Potential role of the endogenous nitric oxide synthase inhibitor ADMA","volume":"10","author":"Sydow K","year":"2005","journal-title":"Vasc Med"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S1567-5688(03)00035-7","article-title":"Hyperhomocysteinemia, endothelial dysfunction, and cardiovascular risk: The potential role of ADMA","volume":"4","author":"Lentz SR","year":"2003","journal-title":"Atheroscler Suppl"},{"key":"e_1_3_2_11_2","doi-asserted-by":"crossref","first-page":"S122","DOI":"10.1016\/j.diabres.2008.09.024","article-title":"ADMA, cardiovascular disease and diabetes","volume":"82","author":"Krzyzanowska K","year":"2008","journal-title":"Diabetes Res Clin Pract"},{"key":"e_1_3_2_12_2","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1161\/CIRCULATIONAHA.108.838268","article-title":"Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community","volume":"119","author":"B\u00f6ger RH","year":"2009","journal-title":"Circulation"},{"key":"e_1_3_2_13_2","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1002\/biof.17","article-title":"Contributions of hyperhomocysteinemia to atherosclerosis: Causal relationship and potential mechanisms","volume":"35","author":"Zhou J","year":"2009","journal-title":"Biofactors"},{"key":"e_1_3_2_14_2","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/10641950802233049","article-title":"Plasma homocysteine concentrations and insulin resistance in preeclampsia","volume":"28","author":"Malek-khosravi S","year":"2009","journal-title":"Hypertens Pregnancy"},{"key":"e_1_3_2_15_2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1080\/08860220701813350","article-title":"Positive Correlation of CRP and Fibrinogen Levels as Cardiovascular Risk Factors in Early Stage of Continuous Ambulatory Peritoneal Dialysis Patients","volume":"30","author":"Tekin IO","year":"2008","journal-title":"Ren Fail"},{"key":"e_1_3_2_16_2","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1046\/j.1365-2796.2002.01019.x","article-title":"Inflammatory bio-markers and cardiovascular risk prediction","volume":"252","author":"Blake GJ","year":"2002","journal-title":"J Intern Med"},{"key":"e_1_3_2_17_2","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1111\/j.1471-0528.2006.01008.x","article-title":"PCOS according to the Rotterdam consensus criteria: Change in prevalence among WHO-II anovulation and association with metabolic factors","volume":"113","author":"Broekmans FJ","year":"2006","journal-title":"BJOG"},{"key":"e_1_3_2_18_2","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S0015-0282(16)41415-9","article-title":"Plasma testosterone free index: A better indicator of plasma androgen activity?","volume":"26","author":"Clark AF","year":"1975","journal-title":"Fertil Steril"},{"key":"e_1_3_2_19_2","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/BF00280883","article-title":"Homeostatic model assessment: Insulin resistance and _-cell function from fasting plasma glucose and insulin concentrations in man","volume":"28","author":"Matthews DR","year":"1985","journal-title":"Diabetologia"},{"key":"e_1_3_2_20_2","first-page":"199","article-title":"Lipid and lipoprotein profile in women with polycystic ovary syndrome","volume":"86","author":"Macut D","year":"2008","journal-title":"Can J Physiol Pharmacol"},{"key":"e_1_3_2_21_2","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1210\/jc.2007-1756","article-title":"A more atherogenic serum lipoprotein profile is present in women with polycystic ovary syndrome: A case-control study","volume":"93","author":"Valkenburg O","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_3_2_22_2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ijgo.2008.01.023","article-title":"Prevalence of symptoms associated with polycystic ovary syndrome","volume":"102","author":"Lindholm A","year":"2008","journal-title":"Int J Gynaecol Obstet"},{"key":"e_1_3_2_23_2","first-page":"67","article-title":"Androgen excess and cardiovascular risk","volume":"32","author":"Rizzo M","year":"2007","journal-title":"Minerva Endocrinol"},{"key":"e_1_3_2_24_2","first-page":"800","article-title":"Testosterone worsens endothelial dysfunction associated with hypercholesterolemia and environmental tobacco smoke exposure in male rabbit aorta","volume":"29","author":"Hutchison SJ","year":"1997","journal-title":"J Am Coll Cardiol"},{"key":"e_1_3_2_25_2","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1210\/jc.2007-0842","article-title":"Asymmetrical dimethylarginine, inflammatory and metabolic parameters in women with polycystic ovary syndrome before and after metformin treatment","volume":"93","author":"Heutling D","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_3_2_26_2","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.atherosclerosis.2004.05.014","article-title":"Acute hyperhomocysteinemia decreases NO bioavailability in healthy adults","volume":"176","author":"Romerio SC","year":"2004","journal-title":"Atherosclerosis"},{"key":"e_1_3_2_27_2","doi-asserted-by":"crossref","first-page":"H2649","DOI":"10.1152\/ajpheart.00548.2005","article-title":"Mechanisms of homocysteine-induced oxidative stress","volume":"289","author":"Tyagi N","year":"2005","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"e_1_3_2_28_2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ejogrb.2006.10.015","article-title":"Plasma homocysteine and polycystic ovary syndrome: The missed link","volume":"131","author":"Badawy A","year":"2007","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"e_1_3_2_29_2","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1161\/01.HYP.0000258405.25330.80","article-title":"Asymmetric Dimethylarginine and Reduced Nitric Oxide Bioavailability in Young Black African Men","volume":"49","author":"Melikian N","year":"2007","journal-title":"Hypertens"},{"key":"e_1_3_2_30_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0009-8981(03)00338-3","article-title":"Serum concentrations of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine in patients with chronic kidney diseases","volume":"336","author":"Fleck C","year":"2003","journal-title":"Clin Chim Acta"}],"container-title":["Annals of Saudi Medicine"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,6,2]],"date-time":"2023-06-02T00:15:08Z","timestamp":1685664908000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.annsaudimed.net\/doi\/10.4103\/0256-4947.65255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["10.4103\/0256-4947.65255"],"URL":"https:\/\/doi.org\/10.4103\/0256-4947.65255","relation":{},"ISSN":["0256-4947","0975-4466"],"issn-type":[{"value":"0256-4947","type":"print"},{"value":"0975-4466","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7]]}}}