{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T08:12:59Z","timestamp":1793779979036,"version":"4.6.1"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anesth Essays Res"],"published-print":{"date-parts":[[2016]]},"DOI":"10.4103\/0259-1162.164675","type":"journal-article","created":{"date-parts":[[2015,9,8]],"date-time":"2015-09-08T02:17:32Z","timestamp":1441678652000},"page":"3","source":"Crossref","is-referenced-by-count":16,"title":["Irreversible pulpitis and achieving profound anesthesia: Complexities and managements"],"prefix":"10.4103","volume":"10","author":[{"given":"Hamid","family":"Badrian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jalil","family":"Modaresi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amin","family":"Davoudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roya","family":"Sabzian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0259-1162.164675-1","first-page":"201","volume-title":"Inflammation and dental pain in man","author":"Ahlquist","year":"1994","journal-title":"Endod Dent Traumatol"},{"key":"key-10.4103\/0259-1162.164675-2","first-page":"244","volume-title":"The effect of systemically administered recombinant human nerve growth factor in healthy human subjects","author":"Petty","year":"1994","journal-title":"Ann Neurol"},{"key":"key-10.4103\/0259-1162.164675-3","first-page":"517","volume-title":"A pilot study of the clinical problem of regionally anesthetizing the pulp of an acutely inflamed mandibular molar","author":"Wallace","year":"1985","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"key-10.4103\/0259-1162.164675-4","first-page":"438","volume-title":"Effect of pulp inflammation on nerve impulse quality with or without anesthesia","author":"Modaresi","year":"2008","journal-title":"J Endod"},{"key":"key-10.4103\/0259-1162.164675-5","first-page":"7","volume-title":"Why can't you achieve adequate regional anesthesia in the presence of infection?","author":"Najjar","year":"1977","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"key-10.4103\/0259-1162.164675-6","first-page":"163","volume-title":"Inflammatory mediators potentiate pain induced by experimental tissue acidosis","author":"Steen","year":"1996","journal-title":"Pain"},{"key":"key-10.4103\/0259-1162.164675-7","first-page":"749","volume-title":"Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin","author":"LaMotte","year":"1992","journal-title":"J Physiol"},{"key":"key-10.4103\/0259-1162.164675-8","first-page":"365785","volume-title":"Dental pulp testing: A review","author":"Chen","year":"2009","journal-title":"Int J Dent"},{"key":"key-10.4103\/0259-1162.164675-9","first-page":"4","volume-title":"Dental injury models: Experimental tools for understanding neuroinflammatory interactions and polymodal nociceptor functions","author":"Byers","year":"1999","journal-title":"Crit Rev Oral Biol Med"},{"key":"key-10.4103\/0259-1162.164675-10","unstructured":"Ingle J, Walton R, Malamed S, Coil J, Khademi J, Kahn F. Preparation for endodontic treatment. In: Ingle JI, Bakland LK, editors. Endodontics. 5th ed. Hamilton: BC Decker Inc.; 2002. p. 357-404."},{"key":"key-10.4103\/0259-1162.164675-11","first-page":"247","volume-title":"Failure of inferior alveolar nerve block in endodontics","author":"Potocnik","year":"1999","journal-title":"Endod Dent Traumatol"},{"key":"key-10.4103\/0259-1162.164675-12","first-page":"26","volume-title":"Local anesthetic failure in endodontics","author":"Hargreaves","year":"2002","journal-title":"Endod Topics"},{"key":"key-10.4103\/0259-1162.164675-13","first-page":"120","volume-title":"Comparing the quality of anaesthesia in normal and inflamed teeth by pulp testing","author":"Modaresi","year":"2005","journal-title":"Aust Endod J"},{"key":"key-10.4103\/0259-1162.164675-14","first-page":"89","volume-title":"Differential block of sensory neuronal voltage-gated sodium channels by lacosamide [(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide], lidocaine, and carbamazepine","author":"Sheets","year":"2008","journal-title":"J Pharmacol Exp Ther"},{"key":"key-10.4103\/0259-1162.164675-15","doi-asserted-by":"crossref","unstructured":"Gould HJ 3rd, England JD, Soignier RD, Nolan P, Minor LD, Liu ZP, et al. Ibuprofen blocks changes in Na v 1.7 and 1.8 sodium channels associated with complete Freund's adjuvant-induced inflammation in rat. J Pain 2004;5:270-80.","DOI":"10.1016\/j.jpain.2004.04.005"},{"key":"key-10.4103\/0259-1162.164675-16","first-page":"399","volume-title":"The efficacy comparison of ibuprofen, acetaminophen-codeine, and placebo premedication therapy on the depth of anesthesia during treatment of inflamed teeth","author":"Modaresi","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"key-10.4103\/0259-1162.164675-17","first-page":"1450","volume-title":"The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis","author":"Parirokh","year":"2010","journal-title":"J Endod"},{"key":"key-10.4103\/0259-1162.164675-18","first-page":"5","volume-title":"Effectiveness of premedication with analgesics vs placebo for success of inferior alveolar nerve block in irreversible pulpitis","author":"Wali","year":"2012","journal-title":"Int J Prosthodont Restor Dent"},{"key":"key-10.4103\/0259-1162.164675-19","first-page":"676","volume-title":"Anesthetic efficacy of the supplemental intraosseous injection of 3% mepivacaine in irreversible pulpitis","author":"Reisman","year":"1997","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"key-10.4103\/0259-1162.164675-20","first-page":"1366","volume-title":"Selective opioid inhibition of small nociceptive neurons","author":"Taddese","year":"1995","journal-title":"Science"},{"key":"key-10.4103\/0259-1162.164675-21","first-page":"90","volume-title":"Peripheral opioid analgesia in teeth with symptomatic inflamed pulps","author":"Uhle","year":"1997","journal-title":"Anesth Prog"},{"key":"key-10.4103\/0259-1162.164675-22","first-page":"379","volume-title":"Effect of preoperative ibuprofen on the success of the inferior alveolar nerve block in patients with irreversible pulpitis","author":"Oleson","year":"2010","journal-title":"J Endod"},{"key":"key-10.4103\/0259-1162.164675-23","first-page":"209","volume-title":"Preoperative oral nonsteroidal anti-inflammatory drugs for the success of the inferior alveolar nerve block in irreversible pulpitis treatment: A systematic review and meta-analysis based on randomized controlled trials","author":"Li","year":"2012","journal-title":"Quintessence Int"}],"container-title":["Anesthesia: Essays and Researches"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:41:59Z","timestamp":1786650119000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0259-1162.164675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016]]}},"alternative-id":["164675"],"URL":"https:\/\/doi.org\/10.4103\/0259-1162.164675","relation":{},"ISSN":["0259-1162"],"issn-type":[{"value":"0259-1162","type":"print"}],"subject":[],"published":{"date-parts":[[2016]]}}}