{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:51:54Z","timestamp":1786650714565,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Ophthalmol"],"published-print":{"date-parts":[[2014]]},"DOI":"10.4103\/0301-4738.111213","type":"journal-article","created":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T07:00:42Z","timestamp":1397113242000},"page":"291","source":"Crossref","is-referenced-by-count":10,"title":["Hyperhomocysteinia is a risk factor for retinal venous occlusion: A case control study"],"prefix":"10.4103","volume":"62","author":[{"given":"Rajiv","family":"Khandekar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahad","family":"Al Wadani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gigani","family":"Salim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Al Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salman","family":"Ramzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0301-4738.111213-1","first-page":"1007","volume-title":"Activation of Hageman factor by L-homocystine","author":"Ratnoff","year":"1968","journal-title":"Science"},{"key":"key-10.4103\/0301-4738.111213-2","first-page":"1136","volume-title":"Meta-analysis of plasma homocysteine, serum folate, serum vitamin B(12), and thermolabile MTHFR genotype as risk factors for retinal vascular occlusive disease","author":"Cahill","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"key-10.4103\/0301-4738.111213-3","first-page":"940","volume-title":"Hyperhomocysteinemia and the methylenetetrahydrofolate reductase 677C-T mutation in patients under 50 years of age affected by central retinal vein occlusion","author":"Di","year":"2004","journal-title":"Ophthalmology"},{"key":"key-10.4103\/0301-4738.111213-4","first-page":"4712","volume-title":"Retinal vein occlusion, homocysteine, and methylene tetrahydrofolate reductase genotype","author":"McGimpsey","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"key-10.4103\/0301-4738.111213-5","first-page":"599","volume-title":"Homocysteine determinants and the evidence to what extent homocysteine determines the risk of coronary heart disease","author":"De","year":"2002","journal-title":"Pharmacol Rev"},{"key":"key-10.4103\/0301-4738.111213-6","first-page":"88","volume-title":"genotype and retinal vascular occlusive disease","author":"Cahill","year":"2001","journal-title":"Br J Ophthalmol"},{"key":"key-10.4103\/0301-4738.111213-7","first-page":"181","volume-title":"Homocysteine and retinal vein occlusion: A population-based study.Am J Ophthalmol","author":"Chua","year":"2005","journal-title":""},{"key":"key-10.4103\/0301-4738.111213-8","first-page":"590","volume-title":"Plasma total homocysteine and retinal vascular disease","author":"Martin","year":"2000","journal-title":"Eye (Lond)"},{"key":"key-10.4103\/0301-4738.111213-9","first-page":"259","volume-title":"Berliner S","author":"Kesler","year":"2008","journal-title":"Comparative analysis of homocysteine concentrations in patients with retinal vein occlusion versus thrombotic and atherosclerotic disorders Blood Coagul Fibrinolysis"},{"key":"key-10.4103\/0301-4738.111213-10","first-page":"23","volume-title":"Hyperhomocysteinemia and central retinal vein occlusion in Iranian population","author":"Moghimi","year":"2008","journal-title":"Int Ophthalmol"},{"key":"key-10.4103\/0301-4738.111213-11","doi-asserted-by":"crossref","unstructured":"Selhub J. Homocystiene metabolism. Annu Rev Nutr 1999;19:217-49. http:\/\/www.annualreviews.org\/doi\/pdf\/10.1146\/annurev.nutr.19.1.217 [last accessed on 2011 Oct 7].","DOI":"10.1146\/annurev.nutr.19.1.217"},{"key":"key-10.4103\/0301-4738.111213-12","unstructured":"US Department of Health and Human Services. Nutrition and Your Health: Dietary Guidelines for Americans. 4 th ed. Washington DC: US Government Printing Office; 1995."},{"key":"key-10.4103\/0301-4738.111213-13","first-page":"1448","volume-title":"Dietary strategies for lowering homocysteine concentrations.Am J Clin Nutr","author":"Riddell","year":"2000","journal-title":""},{"key":"key-10.4103\/0301-4738.111213-14","first-page":"852","volume-title":"Effect of dietary patterns on serum homocysteine: Results of a randomized, controlled feeding study.Circulation","author":"Appel","year":"2000","journal-title":""},{"key":"key-10.4103\/0301-4738.111213-15","first-page":"2015","volume-title":"Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis","author":"Homocysteine","year":"2002","journal-title":"JAMA"},{"key":"key-10.4103\/0301-4738.111213-16","first-page":"224","volume-title":"Homocysteine and stroke: Evidence on a causal link from mendelian randomisation","author":"Casas","year":"2005","journal-title":"Lancet"},{"key":"key-10.4103\/0301-4738.111213-17","first-page":"1007","volume-title":"Homocysteinemia is a risk factor for aortic dissection","author":"Takagi","year":"2005","journal-title":"Med Hypotheses"},{"key":"key-10.4103\/0301-4738.111213-18","first-page":"945","volume-title":"Role of hyperhomocysteinemia in aortic disease","author":"Giusti","year":"2004","journal-title":"Cell Mol Biol (Noisy-le-grand)"},{"key":"key-10.4103\/0301-4738.111213-19","first-page":"495","volume-title":"Hyperhomocysteinemia and retinal vascular occlusive disease","author":"Abu","year":"2002","journal-title":"Eur J Ophthalmol"},{"key":"key-10.4103\/0301-4738.111213-20","first-page":"493","volume-title":"Hyperhomocysteinemia: A new risk factor for central retinal vein occlusion","author":"Vine","year":"2000","journal-title":"Trans Am Ophthalmol Soc"},{"key":"key-10.4103\/0301-4738.111213-21","first-page":"1246","volume-title":"Hyperhomocysteinemia and low plasma folate as risk factors for central retinal vein occlusion: a case-control study in a Chinese population.Graefes Arch Clin Exp Ophthalmol","author":"Gao","year":"2006","journal-title":""},{"key":"key-10.4103\/0301-4738.111213-22","first-page":"4067","volume-title":"Plasma homocysteine and cysteine levels in retinal vein occlusion","author":"Pinna","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"key-10.4103\/0301-4738.111213-23","first-page":"633","volume-title":"Hyperhomocysteinaemia: Risk of retinal vascular occlusion","author":"Yaghoubi","year":"2004","journal-title":"East Mediterr Health J"},{"key":"key-10.4103\/0301-4738.111213-24","first-page":"154","volume-title":"Hyperhomocysteinemia in central retinal vein occlusion in young adults","author":"Parodi","year":"2003","journal-title":"Semin Ophthalmol"},{"key":"key-10.4103\/0301-4738.111213-25","first-page":"340","volume-title":"Hyperhomocysteinemia and the MTHFR C677T mutation in central retinal vein occlusion","author":"Larsson","year":"2000","journal-title":"Acta Ophthalmol Scand"},{"key":"key-10.4103\/0301-4738.111213-26","first-page":"233","volume-title":"Atherosclerotic and thrombophilic risk factors in patients with recurrent central retinal vein occlusion","author":"Sodi","year":"2008","journal-title":"Eur J Ophthalmol"},{"key":"key-10.4103\/0301-4738.111213-27","doi-asserted-by":"crossref","unstructured":"Rogers SL, McIntosh RL, Lim L, Mitchell P, Cheung N, Kowalski JW, et al. Natural history of branch retinal vein occlusion: An evidence-based systematic review. Ophthalmology 2010;117:1094-1101. e5.","DOI":"10.1016\/j.ophtha.2010.01.058"},{"key":"key-10.4103\/0301-4738.111213-28","first-page":"307","volume-title":"Retinal vein occlusions: A review for the internist","author":"Marcucci","year":"2011","journal-title":"Intern Emerg Med"},{"key":"key-10.4103\/0301-4738.111213-29","first-page":"989","volume-title":"Homocysteine, folates, and the eye.Eye (Lond)","author":"Wright","year":"2008","journal-title":""},{"key":"key-10.4103\/0301-4738.111213-30","first-page":"308","volume-title":"Retinal vein thrombosis: Risk factors, pathogenesis and therapeutic approach","author":"Prisco","year":"2002","journal-title":"Pathophysiol Haemost Thromb"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:22:09Z","timestamp":1786648929000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0301-4738.111213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014]]}},"alternative-id":["111213"],"URL":"https:\/\/doi.org\/10.4103\/0301-4738.111213","relation":{},"ISSN":["0301-4738"],"issn-type":[{"value":"0301-4738","type":"print"}],"subject":[],"published":{"date-parts":[[2014]]}}}