{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:27:18Z","timestamp":1786728438835,"version":"build-2736575974"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the safety, efficacy and potential risks of Artiflex foldable iris-fixated phakic intraocular lens (pIOL) implantation for the management of myopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Seventy-eight eyes of 40 consecutive patients with a mean spherical refraction of \u201311.70 \u00b1 3.77 diopters (D; range \u20135.50 to \u201317.5 D) were included in this prospective, noncomparative, interventional case series. Main parameters assessed were uncorrected visual acuity (UCVA), best-spectacle corrected visual acuity (BSCVA), corneal topography (Orbscan II, BauchandLomb, Rochester, NY, USA), manifest and cycloplegic refractive errors, endothelial cell density (ECD) and applanation tonometry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>After 2 years, BSCVA was 20\/40 or better in 82% of the eyes and UCVA was 20\/40 or better in 84% of the eyes. After 1 month, 1 year, and 2 years, 51.3% (37 of 72 eyes), 58.9% (46 of 78 eyes) and 76.0% (38 of 50 eyes) of eyes gained 1 line or more of BSCVA, respectively. Compared to preoperative values, the mean endothelial cell loss was 2.6% at 1 month, 4.9% at 1 year and 7.4% at 2 years. Pigmented or non-pigmented precipitates were observed in17 eyes (21.7%) which were treated with topical corticosteroids. At the second postoperative year, pigmented precipitates persisted in nine eyes. However, this was not associated with a loss of BSCVA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The implantation of Artiflex pIOL is an effective surgical option for the management of high myopia. The most common complication observed within 2 years of follow-up was accumulation of pigmented precipitates with no effect on the final BSCVA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0301-4738.91340","type":"journal-article","created":{"date-parts":[[2011,12,30]],"date-time":"2011-12-30T11:45:55Z","timestamp":1325245555000},"page":"23-28","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Foldable iris-fixated phakic intraocular lens implantation for the correction of myopia: Two years of follow-up"],"prefix":"10.4103","volume":"60","author":[{"given":"Yusuf","family":"Ozert\u00fcrk","sequence":"first","affiliation":[{"name":"Kartal Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Kubaloglu","sequence":"additional","affiliation":[{"name":"Kartal Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esin Sogutlu","family":"Sari","sequence":"additional","affiliation":[{"name":"Kartal Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arif","family":"Koytak","sequence":"additional","affiliation":[{"name":"Department of Opthalmology, Bezmialem University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musa","family":"Capkin","sequence":"additional","affiliation":[{"name":"Kartal Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levent","family":"Ak\u00e7ay","sequence":"additional","affiliation":[{"name":"Kartal Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pinar Sorgun","family":"Evcili","sequence":"additional","affiliation":[{"name":"Kartal Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20251009","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3928\/1081-597X-20060101-07","article-title":"A quality of life comparison of people wearing spectacles or contact lenses or having undergone refractive surgery","volume":"22","author":"Pesudovs","year":"2006","journal-title":"J Refract Surg"},{"key":"R2-20251009","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S0161-6420(99)90103-3","article-title":"Phakic anterior chamber lenses for the correction of myopia: A 7-year cumulative analysis of complications in 263 cases","volume":"106","author":"Ali\u00f3","year":"1999","journal-title":"Ophthalmology"},{"key":"R3-20251009","doi-asserted-by":"crossref","first-page":"312","DOI":"10.3928\/1081-597X-19980501-15","article-title":"Iatrogenic keratectasia after laser in situ keratomileusis","volume":"14","author":"Seiler","year":"1998","journal-title":"J Refract Surg"},{"key":"R4-20251009","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0161-6420(99)90000-3","article-title":"Complications of laser in situ keratomileusis for the correction of myopia","volume":"106","author":"Stulting","year":"1999","journal-title":"Ophthalmology"},{"key":"R5-20251009","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/S0161-6420(02)01164-8","article-title":"A randomized paired eye comparison of two techniques for treating moderately high myopia: LASIK and Artisan phakic lens","volume":"109","author":"Malecaze","year":"2002","journal-title":"Ophthalmology"},{"key":"R6-20251009","doi-asserted-by":"crossref","first-page":"268","DOI":"10.3928\/1081-597X-19970501-13","article-title":"Surgical correction of high myopia in phakic eyes with Worst-Fechner myopia intraocular lenses","volume":"13","author":"Perez-Santonja","year":"1997","journal-title":"J Refract Surg"},{"key":"R7-20251009","doi-asserted-by":"crossref","first-page":"251","DOI":"10.4103\/0301-4738.27950","article-title":"A retrospective analysis of the first Indian experience on Artisan phakic intraocular lens","volume":"54","author":"Senthil","year":"2006","journal-title":"Indian J Ophthalmol"},{"key":"R8-20251009","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1016\/S0886-3350(02)01210-5","article-title":"Long-term endothelial changes in phakic eyes with posterior chamber intraocular lenses","volume":"28","author":"Dejaco-Ruhswurm","year":"2002","journal-title":"J Cataract Refract Surg"},{"key":"R9-20251009","doi-asserted-by":"crossref","first-page":"286","DOI":"10.3928\/1081-597X-19910701-09","article-title":"Correction of myopia by implantation of a concave Worst-iris claw lens into phakik eyes","volume":"7","author":"Fechner","year":"1991","journal-title":"Refract Corneal Surg"},{"key":"R10-20251009","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.ophtha.2003.05.025","article-title":"Initial results of endothelial cell counts after Artisan lens for phakic eyes: An evaluation of the United States Food and Drug Administration Ophtec Study","volume":"111","author":"Pop","year":"2004","journal-title":"Ophthalmology"},{"key":"R11-20251009","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/S0161-6420(01)00548-6","article-title":"Adjustable refractive surgery: 6-mm Artisan lens plus laser in situ keratomileusis for the correction of high myopia","volume":"108","author":"Guell","year":"2001","journal-title":"Ophthalmology"},{"key":"R12-20251009","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/S0161-6420(02)00964-8","article-title":"Comparison of iris-fixed Artisan lens implantation with Excimer laser in situ keratomileusis in correcting myopia between -9.00 and -19.50 diopters: A randomized study","volume":"109","author":"el Danasoury","year":"2002","journal-title":"Ophthalmology"},{"key":"R13-20251009","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.ophtha.2008.12.059","article-title":"Foldable Artiflex phakic intraocular lens for the correction of myopia: Two-year follow-up results of a prospective European multicenter study","volume":"116","author":"Dick","year":"2009","journal-title":"Ophthalmology"},{"key":"R14-20251009","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/S0886-3350(00)00665-9","article-title":"Searching for the perfect phakic intraocular lens","volume":"26","author":"Kohnen","year":"2000","journal-title":"J Cataract Refract Surg"},{"key":"R15-20251009","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.1016\/j.ophtha.2005.06.036","article-title":"Short-term follow-up after implantation of a foldable iris-fixated intraocular lens in phakic eyes","volume":"112","author":"Tehrani","year":"2005","journal-title":"Ophthalmology"},{"key":"R16-20251009","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/S0161-6420(02)01170-3","article-title":"Artisan phakic intraocular lens for myopia: Short-term results of a prospective, multicenter study: The Artisan Lens Study Group","volume":"109","author":"Maloney","year":"2002","journal-title":"Ophthalmology"},{"key":"R17-20251009","first-page":"630","article-title":"US clinical investigation of the Artisan myopia lens for the correction of high myopia in phakic eyes: Report of the results of phases 1 and 2, and interim phase 3","volume":"71","author":"Alexander","year":"2000","journal-title":"Optometry"},{"key":"R18-20251009","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/S0886-3350(00)00545-9","article-title":"Multicenter study of the Artisan phakic intraocular lens","volume":"26","author":"Budo","year":"2000","journal-title":"J Cataract Refract Surg"},{"key":"R19-20251009","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S0161-6420(02)01447-1","article-title":"Toric phakic intraocular lens: European multicenter study","volume":"110","author":"Dick","year":"2003","journal-title":"Ophthalmology"},{"key":"R20-20251009","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/s00347-004-0990-8","article-title":"Phakic intraocular lenses: Current status and limitations [in German]","volume":"101","author":"Dick","year":"2004","journal-title":"Ophthalmologe"},{"key":"R21-20251009","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.ophtha.2006.09.029","article-title":"Long-term study of Artisan phakic intraocular lens implantation for the correction of moderate to high myopia: Ten-year follow-up results","volume":"114","author":"Tahzib","year":"2007","journal-title":"Ophthalmology"},{"key":"R22-20251009","doi-asserted-by":"crossref","first-page":"634","DOI":"10.3928\/1081-597X-20011101-01","article-title":"Iris-claw phakic intraocular lens for high myopia","volume":"17","author":"Landesz","year":"2001","journal-title":"J Refract Surg"},{"key":"R23-20251009","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.ophtha.2007.05.036","article-title":"Long-term follow-up of endothelial cell change after Artisan phakic intraocular lens implantation","volume":"115","author":"Saxena","year":"2008","journal-title":"Ophthalmology"},{"key":"R24-20251009","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.ajo.2006.07.021","article-title":"Iris-supported phakic lenses (rigid vs foldable version) for treating moderately high myopia: Randomized paired eye comparison","volume":"142","author":"Coullet","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"R25-20251009","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jcrs.2007.08.037","article-title":"Position of rigid and foldable iris-fixated myopic phakic intraocular lens models evaluated by Scheimpflug photography","volume":"34","author":"Kohnen","year":"2008","journal-title":"J Cataract Refract Surg"},{"key":"R27-20251009","doi-asserted-by":"crossref","first-page":"697","DOI":"10.3928\/1081-597X-20021101-06","article-title":"Artisan phakic iris claw intraocular lens for high primary and secondary hyperiopa","volume":"18","author":"Ali\u00f3","year":"2002","journal-title":"J Refract Surg"},{"key":"R28-20251009","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.jcrs.2004.09.034","article-title":"Pigment dispersion and Artisan phakic intraocular lenses: Crystalline lens rise as a safety criterion","volume":"31","author":"Ba\u00efkoff","year":"2005","journal-title":"J Cataract Refract Surg"},{"key":"R29-20251009","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/j.jcrs.2006.02.082","article-title":"Recurrent intraocular inflammation after implantation of the Artiflex phakic intraocular lens for the correction of high myopia","volume":"32","author":"Tahzib","year":"2006","journal-title":"J Cataract Refract Surg"}],"container-title":["Indian Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/02223307-201260010-00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:27:03Z","timestamp":1786724823000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/02223307-201260010-00005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.4103\/0301-4738.91340","relation":{},"ISSN":["0301-4738","1998-3689"],"issn-type":[{"value":"0301-4738","type":"print"},{"value":"1998-3689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1]]},"assertion":[{"value":"2011-01-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-09-10","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}