{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T23:01:59Z","timestamp":1777330919112,"version":"3.51.4"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"24","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,12,20]]},"DOI":"10.4103\/0366-6999.195472","type":"journal-article","created":{"date-parts":[[2016,12,9]],"date-time":"2016-12-09T09:36:54Z","timestamp":1481276214000},"page":"2907-2912","source":"Crossref","is-referenced-by-count":17,"title":["Long-term Effects of Antihypertensive Drug Use and New-onset Osteoporotic Fracture in Elderly Patients"],"prefix":"10.1097","volume":"129","author":[{"given":"Hung-Yi","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai-Yan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei-Ling","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Sheng","family":"Liou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwo-Ping","family":"Jong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-2-20210129","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1536\/ihj.49.205","article-title":"Long-term effects of antihypertensive drugs on the risk of new-onset diabetes in elderly Taiwanese hypertensives","volume":"49","author":"Liou","year":"2008","journal-title":"Int Heart J"},{"key":"R2-2-20210129","first-page":"2740","article-title":"Prevalence of osteoporosis and vertebral fractures and related factors in patients with ankylosing spondylitis","volume":"127","author":"Ulu","year":"2014","journal-title":"Chin Med J"},{"key":"R3-2-20210129","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1007\/s00198-011-1881-x","article-title":"Persistence with intravenous zoledronate in elderly patients with osteoporosis","volume":"23","author":"Lee","year":"2012","journal-title":"Osteoporos Int"},{"key":"R4-2-20210129","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1007\/s00198-006-0172-4","article-title":"An estimate of the worldwide prevalence and disability associated with osteoporotic fractures","volume":"17","author":"Johnell","year":"2006","journal-title":"Osteoporos Int"},{"key":"R5-2-20210129","doi-asserted-by":"crossref","first-page":"206","DOI":"10.2174\/1874467208666150507105105","article-title":"Essential roles of intracellular calcium release channels in muscle, brain, metabolism, and aging","volume":"8","author":"Nordin","year":"2015","journal-title":"Curr Mol Pharmacol"},{"key":"R6-2-20210129","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1097\/MD.0000000000000532","article-title":"Risk factors and incidence of repeat osteoporotic fractures among the elderly in Taiwan: A population-based cohort study","volume":"94","author":"Hsiao","year":"2015","journal-title":"Medicine (Baltimore"},{"key":"R7-2-20210129","doi-asserted-by":"crossref","first-page":"516","DOI":"10.7326\/0003-4819-133-7-200010030-00010","article-title":"Low-dose hydrochlorothiazide and preservation of bone mineral density in older adults. A randomized, double-blind, placebo-controlled trial","volume":"133","author":"LaCroix","year":"2000","journal-title":"Ann Intern Med"},{"key":"R8-2-20210129","first-page":"2909","article-title":"GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women","volume":"91","author":"Lepsen","year":"2015","journal-title":"J Clin Endocrinol Metab"},{"key":"R9-2-20210129","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0895-7061(03)00845-8","article-title":"Effect of quinapril, quinapril-hydrochlorothiazide, and enalapril on the bone mass of hypertensive subjects: Relationship with angiotensin converting enzyme polymorphisms","volume":"16","author":"P\u00e9rez-Castrill\u00f3n","year":"2003","journal-title":"Am J Hypertens"},{"key":"R10-2-20210129","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/j.1365-2796.2006.01695.x","article-title":"Effects of antihypertensive drug treatments on fracture outcomes: A meta-analysis of observational studies","volume":"260","author":"Wiens","year":"2006","journal-title":"J Intern Med"},{"key":"R11-2-20210129","doi-asserted-by":"crossref","first-page":"E610","DOI":"10.1503\/cmaj.131330","article-title":"Assessment and management of falls in older people","volume":"186","author":"Kwan","year":"2014","journal-title":"CMAJ"},{"key":"R12-2-20210129","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1210\/jc.2014-4180","article-title":"Relationship of bone metabolism biomarkers and periodontal disease: The Osteoporotic Fractures in Men (MrOS) Study","volume":"91","author":"Schulze-Sp\u00e4te","year":"2015","journal-title":"J Clin Endocrinol Metab"},{"key":"R13-2-20210129","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1001\/archinternmed.2008.526","article-title":"Loop diuretic use and fracture in postmenopausal women: Findings from the Women's Health Initiative","volume":"169","author":"Carbone","year":"2009","journal-title":"Arch Intern Med"},{"key":"R14-2-20210129","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1002\/jbmr.356","article-title":"Risk of fractures in older adults using antihypertensive medications","volume":"26","author":"Solomon","year":"2011","journal-title":"J Bone Miner Res"},{"key":"R15-2-20210129","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1001\/jama.1991.03460030076032","article-title":"Thiazide diuretics and the risk of hip fracture. Results from the Framingham Study","volume":"265","author":"Felson","year":"1991","journal-title":"JAMA"},{"key":"R16-2-20210129","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1056\/NEJM199208273270908","article-title":"The prevention and treatment of osteoporosis","volume":"327","author":"Riggs","year":"1992","journal-title":"N Engl J Med"},{"key":"R17-2-20210129","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1056\/NEJM199002013220502","article-title":"Thiazide diuretic agents and the incidence of hip fracture","volume":"322","author":"LaCroix","year":"1990","journal-title":"N Engl J Med"},{"key":"R18-2-20210129","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1002\/jcp.25096","article-title":"Beta adrenergic receptor stimulation suppresses cell migration in association with cell cycle transition in osteoblasts-live imaging analyses based on FUCCI system","volume":"231","author":"Katsumura","year":"2016","journal-title":"J Cell Physiol"},{"key":"R19-2-20210129","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0092-8674(02)01049-8","article-title":"Leptin regulates bone formation via the sympathetic nervous system","volume":"111","author":"Takeda","year":"2002","journal-title":"Cell"},{"key":"R20-2-20210129","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1111\/ggi.12359","article-title":"Medication use and fall-risk assessment for falls in an acute care hospital","volume":"15","author":"Chiu","year":"2015","journal-title":"Geriatr Gerontol Int"},{"key":"R21-2-20210129","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1001\/jama.292.11.1326","article-title":"Use of beta-blockers and risk of fractures","volume":"292","author":"Schlienger","year":"2004","journal-title":"JAMA"},{"key":"R22-2-20210129","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1007\/s00198-007-0354-8","article-title":"Beta-blocker use and risk of fractures in men and women from the general population: The MONICA\/KORA Augsburg Cohort Study","volume":"18","author":"Meisinger","year":"2007","journal-title":"Osteoporos Int"},{"key":"R23-2-20210129","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1359\/JBMR.041202","article-title":"beta-Blocker use, BMD, and fractures in the study of osteoporotic fractures","volume":"20","author":"Reid","year":"2005","journal-title":"J Bone Miner Res"},{"key":"R24-2-20210129","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1111\/j.1532-5415.2005.53178_7.x","article-title":"Beta-blocker use, bone mineral density, and fracture risk in older women: Results from the Epidemiologie de l\u2019Osteoporose Prospective Study","volume":"53","author":"Levasseur","year":"2005","journal-title":"J Am Geriatr Soc"},{"key":"R25-2-20210129","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1001\/2013.jamainternmed.469","article-title":"The risk of hip fracture after initiating antihypertensive drugs in the elderly","volume":"172","author":"Butt","year":"2012","journal-title":"Arch Intern Med"},{"key":"R26-2-20210129","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1097\/01.hjh.0000203845.26690.cb","article-title":"Treatment with beta-blockers, ACE inhibitors, and calcium-channel blockers is associated with a reduced fracture risk: A nationwide case-control study","volume":"24","author":"Rejnmark","year":"2006","journal-title":"J Hypertens"},{"key":"R27-2-20210129","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s00441-015-2115-x","article-title":"Effects of the 1, 4-dihydropyridine L-type calcium channel blocker benidipine on bone marrow stromal cells","volume":"361","author":"Ma","year":"2015","journal-title":"Cell Tissue Res"},{"key":"R28-2-20210129","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1111\/joim.12339","article-title":"Efficacy, effectiveness and side effects of medications used to prevent fractures","volume":"277","author":"Reid","year":"2015","journal-title":"J Intern Med"},{"key":"R29-2-20210129","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/s00774-012-0389-6","article-title":"Fracture risk is increased by the complication of hypertension and treatment with calcium channel blockers in postmenopausal women with type 2 diabetes","volume":"31","author":"Takaoka","year":"2013","journal-title":"J Bone Miner Metab"},{"key":"R30-2-20210129","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ijcard.2015.01.072","article-title":"Risk of fractures in subjects with antihypertensive medications: A nationwide claim study","volume":"184","author":"Choi","year":"2015","journal-title":"Int J Cardiol"}],"container-title":["Chinese Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.4103\/0366-6999.195472","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T19:41:47Z","timestamp":1623958907000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00029330-201612200-00002"}},"subtitle":["A Population-based Longitudinal Cohort Study"],"short-title":[],"issued":{"date-parts":[[2016,12,20]]},"references-count":30,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.4103\/0366-6999.195472","relation":{},"ISSN":["0366-6999"],"issn-type":[{"value":"0366-6999","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12,20]]}}}