{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:35:52Z","timestamp":1787841352149,"version":"build-2784847793"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:p>\n                    <jats:bold>Burkholderia pseudomallei<\/jats:bold>\n                    , a Gram-negative bacillus is the causative agent of Melioidosis, a glanders-like disease, primarily a disease of animals. Melioidosis has been only a rare and sporadic disease in humans outside its endemic region. Currently, diagnosis of\n                    <jats:italic toggle=\"yes\">B. pseudomallei<\/jats:italic>\n                    in the clinical laboratory is very difficult, owing to low awareness of physicians to the nonspecific clinical manifestations, lack of responsiveness among microbiologists outside endemic areas, identification systems in the average sentinel laboratory, and the biosafety conditions necessary to process these organisms. We report a case of chronic left hip joint effusion in a known case of diabetes mellitus. Gram stain of computed tomography (CT)-guided aspirate from the joint revealed Gram-negative bacilli along with pus cells. Culture was confirmed as\n                    <jats:italic toggle=\"yes\">Burkholderia pseudomallei<\/jats:italic>\n                    on\n                    <jats:italic toggle=\"yes\">Vitek2C<\/jats:italic>\n                    , which was sensitive to ceftazidime and trimethoprim\/sulfmethoxazole. Unfortunately, patient could not be started on appropriate antibiotics due to delay in detection and patient succumbed to severe septicemia. This case is reported to highlight importance of automated identification and sensitivity especially in nonendemic areas and unusual antibiogram of this organism for which disc diffusion method is not standardized.\n                  <\/jats:p>","DOI":"10.4103\/0377-4929.125373","type":"journal-article","created":{"date-parts":[[2014,1,18]],"date-time":"2014-01-18T01:32:10Z","timestamp":1390008730000},"page":"460-463","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Chronic suppurative joint effusion due to burkholderia pseudomallei: A case report"],"prefix":"10.4103","volume":"56","author":[{"given":"Madhavi","family":"Deshmukh","sequence":"first","affiliation":[{"name":"Department of Microbiology, Dhruv Pathology and Molecular Diagnostic Laboratory, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shailendra","family":"Mundhada","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Dhruv Pathology and Molecular Diagnostic Laboratory, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250920","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1086\/318116","article-title":"Endemic Melioidosis in tropical Northern Australia:10- year prospective study and review of literature","volume":"3","author":"Currie","year":"2000","journal-title":"Clin Infect Dis"},{"key":"R2-20250920","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1128\/CMR.4.1.52","article-title":"Melioidosis: Tip of iceberg","volume":"4","author":"Dance","year":"1991","journal-title":"Clin Microbiol Rev"},{"key":"R3-20250920","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1586\/14760584.7.9.1357","article-title":"Strategies toward vaccines against Burkholderia mallei and Burkholderia pseudomallei","volume":"7","author":"Bondi","year":"2008","journal-title":"Expert Rev Vaccines"},{"issue":"1","key":"R7-20250920","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1128\/CMR.4.1.52","article-title":"Melioidosis: The tip of the iceberg?","volume":"4","year":"1991","journal-title":"D A Dance Clin. 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Rev."},{"key":"R8-20250920","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1259\/bjr\/15785231","article-title":"Spectrum of imaging findings in melioidosis","volume":"82","author":"Muttarak","year":"2009","journal-title":"Br J Radiol"},{"key":"R9-20250920","first-page":"140","article-title":"Melioidosis: An emerging infectious disease","volume":"51","author":"Raja","year":"2005","journal-title":"J Postgrad Med"},{"key":"R11-20250920","first-page":"679","article-title":"Halving the mortality of severe melioidosis by ceftazidime","volume":"2","author":"White","year":"1989","journal-title":"Lancet"},{"key":"R12-20250920","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1093\/jac\/24.3.295","article-title":"The antimicrobial susceptibility of Pseudomanas pseudomallei: Emergence of resistance in vitro and during treatment","volume":"24","author":"Dance","year":"1989","journal-title":"J Antimicrob Chemother"},{"key":"R13-20250920","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/jac\/37.3.611","article-title":"In-vitro activity of carbapenem antibiotics against beta-lactam susceptible and resistant strains of Burkholderia pseudomallei","volume":"37","author":"Smith","year":"1996","journal-title":"J Antimicrob Chemother"},{"key":"R14-20250920","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1128\/AAC.48.5.1763-1765.2004","article-title":"Outcomes of patients with melioidosis treated with meropenem. Antimicrob","volume":"48","author":"Cheng","year":"2004","journal-title":"Agents Chemother"},{"key":"R15-20250920","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/infdis\/153.1.167","article-title":"In vitro susceptibilty of strains of Pseudomonas pseudomallei isolated in Thailand and Hong Kong to some newer \u03b2 -lactam antibiotics and quinolone derivatives","volume":"153","author":"Chau","year":"1986","journal-title":"J Infect Dis"},{"key":"R16-20250920","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1086\/520218","article-title":"A comparison of chloramphenicol, trimethoprim-sulfamethoxazole, and doxycycline with doxycycline alone as maintenance therapy for melioidosis","volume":"29","author":"Chaowagul","year":"1999","journal-title":"Clin Infect Dis"},{"key":"R17-20250920","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1099\/jmm.0.45766-0","article-title":"Evaluation of lipopolysaccharide and capsular polysaccharide as subunit vaccines against experimental melioidosis","volume":"53","author":"Nelson","year":"2004","journal-title":"J Med Microbiol"}],"container-title":["Indian Journal of Pathology and Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00004270-201356040-00032","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:50:12Z","timestamp":1787838612000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00004270-201356040-00032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.4103\/0377-4929.125373","relation":{},"ISSN":["0377-4929","0974-5130"],"issn-type":[{"value":"0377-4929","type":"print"},{"value":"0974-5130","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10]]}}}