{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:05:13Z","timestamp":1790809513374,"version":"4.1.0"},"reference-count":36,"publisher":"Scientific Scholar","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Dermatol Venereol Leprol"],"published-print":{"date-parts":[[2013]]},"DOI":"10.4103\/0378-6323.120723","type":"journal-article","created":{"date-parts":[[2013,10,29]],"date-time":"2013-10-29T09:18:52Z","timestamp":1383038332000},"page":"772","source":"Crossref","is-referenced-by-count":21,"title":["Estimation of serum level of interleukin-17 and interleukin-4 in leprosy, towards more understanding of leprosy immunopathogenesis"],"prefix":"10.25259","volume":"79","author":[{"given":"Enas","family":"Attia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihan","family":"Hussein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noha","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwa","family":"Abdallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanaa","family":"Emam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","reference":[{"key":"key-10.4103\/0378-6323.120723-1","first-page":"1079","volume-title":"Leprosy","author":"Lockwood","year":"2006","journal-title":"Clin Evid"},{"key":"key-10.4103\/0378-6323.120723-2","first-page":"255","volume-title":"Classification of leprosy according to immunity.A five-group system","author":"Ridley","year":"1966","journal-title":"Int J Lepr Other Mycobact Dis"},{"key":"key-10.4103\/0378-6323.120723-3","first-page":"441","volume-title":"Genetics of susceptibility to leprosy","author":"Fitness","year":"2002","journal-title":"Genes Immun"},{"key":"key-10.4103\/0378-6323.120723-4","first-page":"1209","volume-title":"Leprosy","author":"Britton","year":"2004","journal-title":"Lancet"},{"key":"key-10.4103\/0378-6323.120723-5","first-page":"385","volume-title":"In vivo responses to Mycobacterium leprae: Antigen presentation, interleukin-2 production, and immune cell phenotypes in naturally occurring leprosy lesions","author":"Longley","year":"1985","journal-title":"Int J Lepr Other Mycobact Dis"},{"key":"key-10.4103\/0378-6323.120723-6","first-page":"749","volume-title":"Immunohistologic assessment of cytokine production of infiltrating cells in various forms of leprosy","author":"Arnoldi","year":"1990","journal-title":"Am J Pathol"},{"key":"key-10.4103\/0378-6323.120723-7","first-page":"277","volume-title":"Defining protective responses to pathogens: Cytokine profiles in leprosy lesions","author":"Yamamura","year":"1991","journal-title":"Science"},{"key":"key-10.4103\/0378-6323.120723-8","first-page":"3639","volume-title":"IL-12 regulates T helper type 1 cytokine responses in human infectious disease","author":"Sieling","year":"1994","journal-title":"J Immunol"},{"key":"key-10.4103\/0378-6323.120723-9","first-page":"3413","volume-title":"Immunohistochemical analysis of cellular infiltrate and gamma interferon, interleukin-12, and inducible nitric oxide synthase expression in leprosy type 1 (reversal) reactions before and during prednisolone treatment","author":"Little","year":"2001","journal-title":"Infect Immun"},{"key":"key-10.4103\/0378-6323.120723-10","first-page":"1427","volume-title":"Expression of Toll-like receptor 2 on human Schwann cells: A mechanism of nerve damage in leprosy","author":"Oliveira","year":"2003","journal-title":"Infect Immun"},{"key":"key-10.4103\/0378-6323.120723-11","first-page":"80","volume-title":"Leprosy reactions.New knowledge","author":"Naafs","year":"1994","journal-title":"Trop Geogr Med"},{"key":"key-10.4103\/0378-6323.120723-12","first-page":"1470","volume-title":"Cytokine patterns of immunologically mediated tissue damage","author":"Yamamura","year":"1992","journal-title":"J Immunol"},{"key":"key-10.4103\/0378-6323.120723-13","first-page":"541","volume-title":"Cytokine mRNA expression in Leprosy: Possible role for interferon gamma and interleukin 12 in reactions (RR and ENL)","author":"Moraes","year":"1999","journal-title":"Scand J Immunol"},{"key":"key-10.4103\/0378-6323.120723-14","first-page":"333","volume-title":"High levels of inflammatory cytokines are associated with poor clinical response to steroid treatment and recurrent episodes of type 1 reactions in leprosy","author":"Manandhar","year":"2002","journal-title":"Clin Exp Immunol"},{"key":"key-10.4103\/0378-6323.120723-15","first-page":"175","volume-title":"Neopterin as a marker for immune system activation","author":"Murr","year":"2002","journal-title":"Curr Drug Metab"},{"key":"key-10.4103\/0378-6323.120723-16","first-page":"5483","volume-title":"Human IL-17: A novel cytokine derived from T cells","author":"Yao","year":"1995","journal-title":"J Immunol"},{"key":"key-10.4103\/0378-6323.120723-17","first-page":"1123","volume-title":"Interleukin 17-producing CD4+effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages","author":"Harrington","year":"2005","journal-title":"Nat Immunol"},{"key":"key-10.4103\/0378-6323.120723-18","first-page":"1133","volume-title":"A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17","author":"Park","year":"2005","journal-title":"Nat Immunol"},{"key":"key-10.4103\/0378-6323.120723-19","first-page":"429","volume-title":"B-cell stimulatory factor-1\/interleukin 4","author":"Paul","year":"1987","journal-title":"Annu Rev Immunol"},{"key":"key-10.4103\/0378-6323.120723-20","first-page":"2620","volume-title":"Interleukin-17 promotes angiogenesis and tumor growth","author":"Numasaki","year":"2003","journal-title":"Blood"},{"key":"key-10.4103\/0378-6323.120723-21","unstructured":"WHO Expert Committee on Leprosy. World Health Organ Tech Rep Ser 1988;768:1-51."},{"key":"key-10.4103\/0378-6323.120723-22","first-page":"888","volume-title":"Interleukin-17 and type 17 helper T cells","author":"Miossec","year":"2009","journal-title":"N Engl J Med"},{"key":"key-10.4103\/0378-6323.120723-23","first-page":"513","volume-title":"Increased (6 exon) interleukin-7 production after M.tuberculosis infection and soluble interleukin-7 receptor expression in lung tissue","author":"Rane","year":"2011","journal-title":"Genes Immun"},{"key":"key-10.4103\/0378-6323.120723-24","first-page":"296","volume-title":"Susceptibility to pulmonary disease due to Mycobacterium avium-intracellulare complex may reflect low IL-17 and high IL-10 responses rather than Th1 deficiency","author":"Lim","year":"2010","journal-title":"Clin Immunol"},{"key":"key-10.4103\/0378-6323.120723-25","first-page":"4187","volume-title":"Mycobacterium bovis BCG-specific Th17 cells confer partial protection against Mycobacterium tuberculosis infection in the absence of gamma interferon","author":"Wozniak","year":"2010","journal-title":"Infect Immun"},{"key":"key-10.4103\/0378-6323.120723-26","first-page":"1962","volume-title":"Distinct, specific IL-17- and IL-22-producing CD4+T cell subsets contribute to the human anti-mycobacterial immune response","author":"Scriba","year":"2008","journal-title":"J Immunol"},{"key":"key-10.4103\/0378-6323.120723-27","first-page":"79","volume-title":"IL-23 and IL-17 in tuberculosis","author":"Khader","year":"2008","journal-title":"Cytokine"},{"key":"key-10.4103\/0378-6323.120723-28","first-page":"132","volume-title":"IL-17 and regulatory cytokines (IL-10 and IL-27) in L.braziliensis infection","author":"Novoa","year":"2011","journal-title":"Parasite Immunol"},{"key":"key-10.4103\/0378-6323.120723-29","first-page":"76","volume-title":"Type 1\/Type 2 immunity in infectious diseases","author":"Spellberg","year":"2001","journal-title":"Clin Infect Dis"},{"key":"key-10.4103\/0378-6323.120723-30","first-page":"65","volume-title":"IgM anti-phenolic glycolipid I and IgG anti-10-kDa heat shock protein antibodies in sera and immune complexes isolated from leprosy patients with or without erythema nodosum leprosum and contacts","author":"Rojas","year":"1997","journal-title":"FEMS Immunol Med Microbiol"},{"key":"key-10.4103\/0378-6323.120723-31","first-page":"103","volume-title":"Serum levels of tumour necrosis factor-alpha and interleukin-1 beta during leprosy reactional states","author":"Sarno","year":"1991","journal-title":"Clin Exp Immunol"},{"key":"key-10.4103\/0378-6323.120723-32","unstructured":"El Saadany S, El Kalla F, Elwan N, El Tatawy R, Helmy A, El Shorbagy SH. Role of mast cells and cytokine profile [TNF-\u03b1, IFN-\u03b3, IL4 and IL-4 mRNA] in different types of leprosy. 2008. Available from: http:\/\/knol.google.com\/k\/sherif-el-saadany\/role-of-mast-cellsand-cytokine profile\/i2p6c6e8rrui\/3. [Last cited on 2013 Jan 10]."},{"key":"key-10.4103\/0378-6323.120723-33","doi-asserted-by":"crossref","unstructured":"Verhagen CE, Wierenga EA, Buffing AA, Chand MA, Faber WR, Das PK. Reversal reaction in borderline leprosy is associated with a polarized shift to type 1-like Mycobacterium leprae T cell reactivity in lesional skin: A follow-up study. J Immunol 1997;159:4474-83.","DOI":"10.4049\/jimmunol.159.9.4474"},{"key":"key-10.4103\/0378-6323.120723-34","first-page":"19","volume-title":"Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells","author":"Zurawski","year":"1994","journal-title":"Immunol Today"},{"key":"key-10.4103\/0378-6323.120723-35","first-page":"466","volume-title":"Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies","author":"Caramori","year":"2008","journal-title":"Eur Respir J"},{"key":"key-10.4103\/0378-6323.120723-36","first-page":"218","volume-title":"Treatment strategies for allergy and asthma","author":"Holgate","year":"2008","journal-title":"Nat Rev Immunol"}],"container-title":["Indian Journal of Dermatology, Venereology, and Leprology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T18:40:18Z","timestamp":1688582418000},"score":1,"resource":{"primary":{"URL":"https:\/\/ijdvl.com\/estimation-of-serum-level-of-interleukin-17-and-interleukin-4-in-leprosy-towards-more-understanding-of-leprosy-immunopathogenesis\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013]]}},"alternative-id":["120723"],"URL":"https:\/\/doi.org\/10.4103\/0378-6323.120723","relation":{},"ISSN":["0378-6323"],"issn-type":[{"value":"0378-6323","type":"print"}],"subject":[],"published":{"date-parts":[[2013]]}}}