{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T10:52:04Z","timestamp":1776077524294,"version":"3.50.1"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2019,8,26]],"date-time":"2019-08-26T00:00:00Z","timestamp":1566777600000},"content-version":"vor","delay-in-days":1089,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Plast Surg"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Background: Silicone oil injection can cause several complications including pain, cellulitis, abscesses, skin compromise, migration, embolism and multiorgan failure. Oil-infested tissue excision remains the solely treatment to prevent such complications. Objectives: The authors evaluate tumor-like excision of the oil-infested tissue as a treatment for patients experiencing silicone injections in the lower limbs, to both preserve aesthetic appearance and solve further risk of complication from silicone. Methods: Between January 2004 and January 2011 a total of 12 consecutive, nonrandomized female patients underwent surgical management of siliconoma of the lower limb. The mean age was 41-years, range from 22 to 61 years and all patients didn\u2019t referred comorbidities. Eight siliconomas were located on the leg and 4 were on the thigh. The mean area of siliconoma was 35 cm2, range from 25 to 60 cm2. Each patient was evaluated by ultrasonography and EchocolorDoppler of the soft tissue and in order to achieve a \u201cstaging\u201d of siliconoma. Results: Healing was uneventful in all cases. Three patients (25%) suffering hypertrophic scarring underwent further injection of corticosteroids to improve hypertrophic scars quality. Two patients (16.6%) required a further session of structural fat grafting to improve thigh\u2019s profile. All patients were satisfied with the cosmetic results and indispositions requiring medical therapy disappeared. Conclusions: Tumor-like excision and immediate reconstruction appears to be a safe and consistent surgical option that preserves aesthetic appearance for patients victims of illegal oil silicone injection of the lower limbs.<\/jats:p>","DOI":"10.4103\/0970-0358.197228","type":"journal-article","created":{"date-parts":[[2016,12,30]],"date-time":"2016-12-30T11:01:46Z","timestamp":1483095706000},"page":"384-389","source":"Crossref","is-referenced-by-count":3,"title":["Siliconomas of the lower limb: Tumour-like excision and reconstruction"],"prefix":"10.1055","volume":"49","author":[{"given":"Tommaso","family":"Agostini","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Centro Chirurgico San Paolo, Pistoia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaella","family":"Perello","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Centro Chirurgico San Paolo, Pistoia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,8,26]]},"reference":[{"key":"key-10.4103\/0970-0358.197228-1","first-page":"95","volume-title":"Rare complication of silicone fluid injection presenting as multiple calcification and skin defect in both legs: A case report","author":"Lee","year":"2015","journal-title":"Int J Low Extrem Wounds"},{"key":"key-10.4103\/0970-0358.197228-2","first-page":"92","volume-title":"Silicone migration and granuloma formation","author":"Altmeyer","year":"2009","journal-title":"J Cosmet Dermatol"},{"key":"key-10.4103\/0970-0358.197228-3","first-page":"95","volume-title":"Severe granulomatous reaction associated with hypercalcemia occurring after silicone soft tissue augmentation of the buttocks: A case report","author":"Camuzard","year":"2014","journal-title":"Aesthetic Plast Surg"},{"key":"key-10.4103\/0970-0358.197228-4","doi-asserted-by":"crossref","unstructured":"Gold HL, Wang I, Meehan S, Sanchez M, Smith GP. Gluteal silicone injections leading to extensive filler migration with induration and arthralgia. Dermatol Online J 2014;21. pii: 13030\/qt4xf2m886.","DOI":"10.5070\/D3212022246"},{"key":"key-10.4103\/0970-0358.197228-5","first-page":"1659","volume-title":"Vulvar siliconoma migrating from injected silicone breast augmentation","author":"Jeng","year":"2005","journal-title":"BJOG"},{"key":"key-10.4103\/0970-0358.197228-6","doi-asserted-by":"crossref","unstructured":"d'Ythurbide G, Kerrou K, Brocheriou I, Hertig A. Reactive amyloidosis complicated by end-stage renal disease 28 years after liquid silicone injection in the buttocks. BMJ Case Rep 2012;2012. pii: Bcr2012006803.","DOI":"10.1136\/bcr-2012-006803"},{"key":"key-10.4103\/0970-0358.197228-7","first-page":"572","volume-title":"Massive injections of adulterated liquid silicone: Local complications and development of autoimmune diseases","author":"Guerrissi","year":"1998","journal-title":"Ann Plast Surg"},{"key":"key-10.4103\/0970-0358.197228-8","first-page":"1220","volume-title":"Skin ulcer: A long-term complication after massive liquid silicone oil infiltration","author":"Carella","year":"2013","journal-title":"Aesthetic Plast Surg"},{"key":"key-10.4103\/0970-0358.197228-9","first-page":"e377","volume-title":"A serious complication due to liquid silicone injection in the legs for cosmetic purpose","author":"Fumo","year":"2013","journal-title":"Clin Ter"},{"key":"key-10.4103\/0970-0358.197228-10","first-page":"342","volume-title":"Secondary lymphoedema of the lower leg as an unusual side-effect of a liquid silicone injection in the hips and buttocks","author":"Gaber","year":"2004","journal-title":"Dermatology"},{"key":"key-10.4103\/0970-0358.197228-11","first-page":"407","volume-title":"Tarsal tunnel syndrome secondary to cosmetic silicone injections","author":"Frey","year":"1993","journal-title":"Foot Ankle"},{"key":"key-10.4103\/0970-0358.197228-12","first-page":"241","volume-title":"Silicone injection causing acute pneumonitis: A case series","author":"Zamora","year":"2009","journal-title":"Lung"},{"key":"key-10.4103\/0970-0358.197228-13","first-page":"233","volume-title":"Silicone pulmonary embolism: Report of 10 cases and review of the literature","author":"Restrepo","year":"2009","journal-title":"J Comput Assist Tomogr"},{"key":"key-10.4103\/0970-0358.197228-14","first-page":"97","volume-title":"Massive systemic silicone embolism: A case report and review of literature","author":"Price","year":"2006","journal-title":"Am J Forensic Med Pathol"},{"key":"key-10.4103\/0970-0358.197228-15","first-page":"834","volume-title":"Subcutaneous silicone injection leading to multi-system organ failure","author":"Clark","year":"2008","journal-title":"Clin Toxicol (Phila)"},{"key":"key-10.4103\/0970-0358.197228-16","doi-asserted-by":"crossref","unstructured":"Anastassov GE, Schulhof S, Lumerman H. Complications after facial contour augmentation with injectable silicone. Diagnosis and treatment. Report of a severe case. Int J Oral Maxillofac Surg 2008;37:955-60.","DOI":"10.1016\/j.ijom.2008.04.020"},{"key":"key-10.4103\/0970-0358.197228-17","first-page":"e120","volume-title":"Facial granuloma after occult silicone injection (siliconoma): A diagnosis not to be missed","author":"Kluger","year":"2009","journal-title":"Eur J Intern Med"},{"key":"key-10.4103\/0970-0358.197228-18","first-page":"635","volume-title":"The employment of suction for the removal of siliconomas","author":"Almeida","year":"1990","journal-title":"Plast Reconstr Surg"},{"key":"key-10.4103\/0970-0358.197228-19","first-page":"21","volume-title":"Ultrasound-assisted liposuction for the removal of siliconomas","author":"Grippaudo","year":"2004","journal-title":"Scand J Plast Reconstr Surg Hand Surg"},{"key":"key-10.4103\/0970-0358.197228-20","first-page":"220","volume-title":"Ultrasound-assisted liposuction as a safe and effective method for the removal of siliconomas","author":"Bassetto","year":"2012","journal-title":"Aesthetic Plast Surg"},{"key":"key-10.4103\/0970-0358.197228-21","first-page":"571","volume-title":"Liposuction and lipofilling for treatment of symptomatic silicone toxicosis of the gluteal region","author":"Salgado","year":"2014","journal-title":"Aesthet Surg J"},{"key":"key-10.4103\/0970-0358.197228-22","first-page":"657","volume-title":"Dermolipectomy of the thighs and buttocks to solve a massive silicone oil injection","author":"Loustau","year":"2009","journal-title":"Aesthetic Plast Surg"},{"key":"key-10.4103\/0970-0358.197228-23","first-page":"367","volume-title":"Use of tissue expanders in reconstruction after excision of multiple large silicone granulomas","author":"Wilke","year":"1993","journal-title":"Ann Plast Surg"},{"key":"key-10.4103\/0970-0358.197228-24","first-page":"331","volume-title":"Breast reconstruction with TRAM flap after subcutaneous mastectomy for injected material (siliconoma)","author":"Lai","year":"2001","journal-title":"Br J Plast Surg"},{"key":"key-10.4103\/0970-0358.197228-25","first-page":"734","volume-title":"The devastating outcome of massive subcutaneous injection of highly viscous fluids in male-to-female transsexuals","author":"Hage","year":"2001","journal-title":"Plast Reconstr Surg"},{"key":"key-10.4103\/0970-0358.197228-26","first-page":"473","volume-title":"A serious complication of illicit silicone injections: Latent silicone embolization syndrome after incision and drainage of local injection site","author":"Purdy-Payne","year":"2015","journal-title":"Surg Infect (Larchmt)"},{"key":"key-10.4103\/0970-0358.197228-27","first-page":"48","volume-title":"Silicone granulomas, a growing problem?","author":"Park","year":"2016","journal-title":"J Clin Aesthet Dermatol"},{"key":"key-10.4103\/0970-0358.197228-28","first-page":"239","volume-title":"Dermal skin substitutes for upper limb reconstruction: Current status, indications, and contraindications","author":"Rehim","year":"2014","journal-title":"Hand Clin"},{"key":"key-10.4103\/0970-0358.197228-29","first-page":"386","volume-title":"Massive de-gloving thigh injury treated by vacuum therapy, dermal regeneration matrix and lipografting","author":"Cherubino","year":"2013","journal-title":"Afr J Paediatr Surg","ISSN":"https:\/\/id.crossref.org\/issn\/0189-6725","issn-type":"print"},{"key":"key-10.4103\/0970-0358.197228-30","first-page":"957","volume-title":"Vacuum-assisted closure, dermal regeneration template and degloved cryopreserved skin as useful tools in subtotal degloving of the lower limb","author":"Dini","year":"2012","journal-title":"Injury"},{"key":"key-10.4103\/0970-0358.197228-31","first-page":"368","volume-title":"The histopathologic features of Integra \u00ae dermal regeneration template","author":"Lee","year":"2015","journal-title":"J Cutan Pathol"}],"container-title":["Indian Journal of Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/0970-0358.197228.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,20]],"date-time":"2022-07-20T08:22:04Z","timestamp":1658305324000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.4103\/0970-0358.197228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":31,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2019,8,26]]},"published-print":{"date-parts":[[2016,9]]}},"URL":"https:\/\/doi.org\/10.4103\/0970-0358.197228","relation":{},"ISSN":["0970-0358","1998-376X"],"issn-type":[{"value":"0970-0358","type":"print"},{"value":"1998-376X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9]]}}}