{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T14:57:59Z","timestamp":1792508279325,"version":"4.5.0"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Several immune-mediated inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus have been linked to an increased risk of venous thromboembolism (VTE). However, the data on ankylosing spondylitis (AS) are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a systematic review and meta-analysis of observational studies that reported odds ratio, relative risk, hazard ratio, or standardized incidence ratio comparing the risk of VTE and possible pulmonary embolism (PE) in patients with AS versus non-AS participants. Pooled risk ratio and 95% confidence intervals were calculated using a random-effect, generic inverse variance method of DerSimonian and Laird.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of 423 potentially relevant articles, three studies met our inclusion criteria and thus, were included in the data analysis. The pooled risk ratio of VTE in patients with AS was 1.60 (95% confidence interval: 1.05\u20132.44). The statistical heterogeneity of this study was high with an I\n                      <jats:sup>2<\/jats:sup>\n                      of 93%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our study demonstrated a statistically significant increased VTE risk among patients with AS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0970-2113.192862","type":"journal-article","created":{"date-parts":[[2017,1,20]],"date-time":"2017-01-20T02:12:03Z","timestamp":1484878323000},"page":"642-645","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":23,"title":["Ankylosing spondylitis and risk of venous thromboembolism: A systematic review and meta-analysis"],"prefix":"10.4103","volume":"33","author":[{"given":"Patompong","family":"Ungprasert","sequence":"first","affiliation":[{"name":"Division of Rheumatology, Mayo Clinic, Rochester, MN, USA"},{"name":"Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narat","family":"Srivali","sequence":"additional","affiliation":[{"name":"Division of Pulmonology and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wonngarm","family":"Kittanamongkolchai","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20251006","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1111\/j.1538-7836.2007.02450.x","article-title":"Incidence and mortality of venous thrombosis: A population-based study","volume":"5","author":"Naess","year":"2007","journal-title":"J Thromb Haemost"},{"key":"R2-20251006","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1002\/ajh.20983","article-title":"Estimated annual numbers of US acute-care hospital patients at risk for venous thromboembolism","volume":"82","author":"Anderson","year":"2007","journal-title":"Am J Hematol"},{"key":"R3-20251006","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/jth.12464","article-title":"Incidence of venous thromboembolism in different ethnic groups: A regional direct comparison study","volume":"12","author":"Liao","year":"2014","journal-title":"J Thromb Haemost"},{"key":"R4-20251006","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3324\/haematol.10516","article-title":"The risk of recurrent venous thromboembolism after discontinuing anticoagulation in patients with acute proximal deep vein thrombosis or pulmonary embolism. 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