{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T14:31:09Z","timestamp":1786717869060,"version":"build-2736575974"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Dent Res"],"published-print":{"date-parts":[[2016]]},"DOI":"10.4103\/0970-9290.179808","type":"journal-article","created":{"date-parts":[[2016,4,7]],"date-time":"2016-04-07T05:24:50Z","timestamp":1460006690000},"page":"15","source":"Crossref","is-referenced-by-count":23,"title":["Efficacy of 10% whole Azadirachta indica (neem) chip as an adjunct to scaling and root planning in chronic periodontitis: A clinical and microbiological study"],"prefix":"10.4103","volume":"27","author":[{"given":"K","family":"Vennila","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Elanchezhiyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sugumari","family":"Ilavarasu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0970-9290.179808-1","first-page":"159","volume-title":"Periodontal diseases: A risk factor to cardiovascular disease","author":"Saini","year":"2010","journal-title":"Ann Card Anaesth","ISSN":"https:\/\/id.crossref.org\/issn\/0971-9784","issn-type":"print"},{"key":"key-10.4103\/0970-9290.179808-2","first-page":"82","volume-title":"Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in human periodontal disease: Occurrence and treatment","author":"Slots","year":"2000","journal-title":"Periodontol"},{"key":"key-10.4103\/0970-9290.179808-3","unstructured":"Newman MG, Takei HH, Klokkevold PR, Carranza KA. Carranza\u2032s Clinical Periodontology. 10 th ed. Los Angeles: Elsevier; 2006. p. 228."},{"key":"key-10.4103\/0970-9290.179808-4","first-page":"79","volume-title":"The acquisition of antibiotic resistance in the periodontal microflora","author":"Walker","year":"2000","journal-title":"Periodontol"},{"key":"key-10.4103\/0970-9290.179808-5","first-page":"507","volume-title":"The role of local drug delivery in the management of periodontal diseases: A comprehensive review","author":"Greenstein","year":"1998","journal-title":"J Periodontol"},{"key":"key-10.4103\/0970-9290.179808-6","first-page":"113","volume-title":"Antibiotic resistance of the subgingival microbiota following local tetracycline therapy","author":"Goodson","year":"1992","journal-title":"Oral Microbiol Immunol"},{"key":"key-10.4103\/0970-9290.179808-7","first-page":"89","volume-title":"Occurrence of doxycycline resistant bacteria in the oral cavity after local administration of doxycycline in patients with periodontal disease","author":"Larsen","year":"1991","journal-title":"Scand J Infect Dis"},{"key":"key-10.4103\/0970-9290.179808-8","first-page":"43","volume-title":"A comparative evaluation of atrigel delivery system (10% doxycycline hyclate) atridox with scaling and root planing and combination therapy in treatment of periodontitis: A clinical study","author":"Javali","year":"2012","journal-title":"J Indian Soc Periodontol","ISSN":"https:\/\/id.crossref.org\/issn\/0972-124X","issn-type":"print"},{"key":"key-10.4103\/0970-9290.179808-9","first-page":"637","volume-title":"Sub gingival minocycline hydrochloride ointment in moderate to severe chronic adult periodontitis: A random, double blind, vehicle controlled, multicenter study","author":"Steenberghe","year":"1993","journal-title":"J Periodontol"},{"key":"key-10.4103\/0970-9290.179808-10","first-page":"24","volume-title":"Topical metronidazole application compared with subgingival scaling.A clinical and microbiological study on recall patients","author":"Stelzel","year":"1996","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0970-9290.179808-11","first-page":"32","volume-title":"Sustained local delivery of chlorhexidine in the treatment of periodontitis: A multi-center study","author":"Soskolne","year":"1997","journal-title":"J Periodontol"},{"key":"key-10.4103\/0970-9290.179808-12","first-page":"97","volume-title":"Review of neem (Azadirachta indica): Thousand problems one solution","author":"Sharma","year":"2011","journal-title":"Int Res J Pharm"},{"key":"key-10.4103\/0970-9290.179808-13","first-page":"102","volume-title":"Neem - A green treasure","author":"Girish","year":"2008","journal-title":"Electron J Biol"},{"key":"key-10.4103\/0970-9290.179808-14","first-page":"1336","volume-title":"Biological activities and medicinal properties of neem (Azadirachta indica)","author":"Biswas","year":"2002","journal-title":"Curr Sci"},{"key":"key-10.4103\/0970-9290.179808-15","first-page":"443","volume-title":"Non-surgical pocket therapy: Mechanical","author":"Cobb","year":"1996","journal-title":"Ann Periodontol"},{"key":"key-10.4103\/0970-9290.179808-16","first-page":"142","volume-title":"Antimicrobial strategies for treatment of periodontal diseases","author":"Goodson","year":"2000","journal-title":"Periodontol"},{"key":"key-10.4103\/0970-9290.179808-17","first-page":"232","volume-title":"Effect of stannous fluoride mouthrinse on dental plaque formation","author":"Tinanoff","year":"1980","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0970-9290.179808-18","first-page":"139","volume-title":"Local delivery of antimicrobial agents in the periodontal pocket","author":"Rams","year":"2000","journal-title":"Periodontol"},{"key":"key-10.4103\/0970-9290.179808-19","first-page":"39","volume-title":"Effect of green tea catechin, a local drug delivery system as an adjunct to scaling and root planing in chronic periodontitis patients: A clinicomicrobiological study","author":"Kudva","year":"2011","journal-title":"J Indian Soc Periodontol","ISSN":"https:\/\/id.crossref.org\/issn\/0972-124X","issn-type":"print"},{"key":"key-10.4103\/0970-9290.179808-20","first-page":"84","volume-title":"Effect of locally delivered Aloe vera gel as an adjunct to scaling and root planning in treatment of chronic periodontitis: A clinical study","author":"Virdi","year":"2012","journal-title":"Indian J Oral Sci","ISSN":"https:\/\/id.crossref.org\/issn\/0976-6944","issn-type":"print"},{"key":"key-10.4103\/0970-9290.179808-21","first-page":"15","volume-title":"Therapeutic potentials of tulsi: From experience to facts","author":"Sen","year":"1993","journal-title":"Drugs News Views"},{"key":"key-10.4103\/0970-9290.179808-22","first-page":"408","volume-title":"Antipyretic, antidiarrhoel, hyporlycemic and hepatoprotective activities of ethyl acetate extract of Acacia catechu in albino rats","author":"Ray","year":"2006","journal-title":"Indian J Pharmacol","ISSN":"https:\/\/id.crossref.org\/issn\/0253-7613","issn-type":"print"},{"key":"key-10.4103\/0970-9290.179808-23","first-page":"314","volume-title":"In vitro antibacterial activity of neem oil","author":"Rao","year":"1986","journal-title":"Indian J Med Res","ISSN":"https:\/\/id.crossref.org\/issn\/0971-5916","issn-type":"print"},{"key":"key-10.4103\/0970-9290.179808-24","first-page":"816","volume-title":"The inhibiting effect of aqueous Azadirachta indica (Neem) extract upon bacterial properties influencing in vitro plaque formation","author":"Wolinsky","year":"1996","journal-title":"J Dent Res"},{"key":"key-10.4103\/0970-9290.179808-25","first-page":"23","volume-title":"The antimicrobial effects of extracts of Azadirachta indica (Neem) and Salvadora persica (Arak) chewing sticks","author":"Almas","year":"1999","journal-title":"Indian J Dent Res","ISSN":"https:\/\/id.crossref.org\/issn\/0970-9290","issn-type":"print"},{"key":"key-10.4103\/0970-9290.179808-26","first-page":"149","volume-title":"Medicinal properties of neem leaves: A review","author":"Subapriya","year":"2005","journal-title":"Curr Med Chem Anticancer Agents"},{"key":"key-10.4103\/0970-9290.179808-27","doi-asserted-by":"crossref","unstructured":"Mahfuzul Hoque MD, Bari ML, Inatsu Y, Juneja VK, Kawamoto S. Antibacterial activity of guava (Psidium guajava L.) and neem (Azadirachta indica A. Juss.) extracts against foodborne pathogens and spoilage bacteria. Foodborne Pathog Dis 2007;4:481-8.","DOI":"10.1089\/fpd.2007.0040"},{"key":"key-10.4103\/0970-9290.179808-28","first-page":"341","volume-title":"Efficacy of a mouth rinse based on leaves of neem tree (Azadirachta indica) in treatment of patients with chronic gingivitis: A double blind randomized control trial","author":"Botelho","year":"2008","journal-title":"J Med Plants Res"},{"key":"key-10.4103\/0970-9290.179808-29","first-page":"638","volume-title":"A comparitive study of in vitro anti-bacterial activity of neem and Miswak extracts against isolated cariogens from dental caries patients","author":"Kumari","year":"2011","journal-title":"J Chem Pharm Res"},{"key":"key-10.4103\/0970-9290.179808-30","first-page":"42","volume-title":"To evaluate the efficacy of neem chip as an adjunct to scaling and root planning in patients with chronic periodontitis","author":"Jain","year":"2012","journal-title":"Indian J Dent Sci"},{"key":"key-10.4103\/0970-9290.179808-31","first-page":"398","volume-title":"To evaluate the antigingivitis and antipalque effect of an Azadirachta indica (neem) mouthrinse on plaque induced gingivitis: A double-blind, randomized, controlled trial","author":"Chatterjee","year":"2011","journal-title":"J Indian Soc Periodontol","ISSN":"https:\/\/id.crossref.org\/issn\/0972-124X","issn-type":"print"},{"key":"key-10.4103\/0970-9290.179808-32","first-page":"218","volume-title":"A new discriminative criterion for the development of Franz diffusion tests for transdermal pharmaceuticals","author":"Baert","year":"2010","journal-title":"J Pharm Pharm Sci"},{"key":"key-10.4103\/0970-9290.179808-33","first-page":"860","volume-title":"Response to intracrevicular controlled delivery of 25% tetracycline from poly(lactide\/glycolide) film strips in SPT patients","author":"Maze","year":"1995","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0970-9290.179808-34","first-page":"1054","volume-title":"Quantitative real-time polymerase chain reaction based on single copy gene sequence for detection of periodontal pathogens","author":"Morillo","year":"2004","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0970-9290.179808-35","first-page":"176","volume-title":"Quantitative analysis of multi-species oral biofilms by TaqMan Real-Time PCR","author":"Suzuki","year":"2005","journal-title":"Clin Med Res"},{"key":"key-10.4103\/0970-9290.179808-36","first-page":"427","volume-title":"The additional value of real-time PCR in the quantitative detection of periodontal pathogens","author":"Boutaga","year":"2006","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0970-9290.179808-37","first-page":"79","volume-title":"Comparison of subgingival bacterial sampling with oral lavage for detection and quantification of periodontal pathogens by real-time polymerase chain reaction","author":"Boutaga","year":"2007","journal-title":"J Periodontol"},{"key":"key-10.4103\/0970-9290.179808-38","first-page":"778","volume-title":"Comparison of culture and real-time PCR for detection and quantification of five putative periodontopathogenic bacteria in subgingival plaque samples","author":"Jerv\u00f8e-Storm","year":"2005","journal-title":"J Clin Periodontol"}],"container-title":["Indian Journal of Dental Research"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:28:52Z","timestamp":1786714132000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0970-9290.179808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016]]}},"alternative-id":["179808"],"URL":"https:\/\/doi.org\/10.4103\/0970-9290.179808","relation":{},"ISSN":["0970-9290"],"issn-type":[{"value":"0970-9290","type":"print"}],"subject":[],"published":{"date-parts":[[2016]]}}}