{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:37:21Z","timestamp":1761896241966},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T00:00:00Z","timestamp":1626048000000},"content-version":"vor","delay-in-days":1928,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Med Paediatr Oncol"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background: Data concerning treatment outcome and prognostic factors in sarcomas of abdomen and pelvis are sparse in literature.Methods and Results: Of 696 patients with nonrhabdomyosarcomatous soft tissue sarcoma registered at our center between June 2003 and December 2012, 112 (16%) patients of sarcomas arising from abdomen and pelvis were identified, of which 88 patients were analyzed for treatment outcome and prognostic factors. The median age was 40 years (range: 1\u201378 years) with a male: female ratio of 0.7:1. Twenty-one (24%) patients were metastatic at baseline. The most common tumor sites were retroperitoneum in 70% patients and abdominal wall in 18% patients. Leiomyosarcoma was the most common histological subtype in 36% patients followed by liposarcoma in 17% patients. Thirty-five (40%) patients had Grade III tumors. Forty-six (52%) patients underwent surgical resection. At a median follow-up of 43 months (range: 2\u201394 months), the 5-year event-free survival (EFS) and overall survival (OS) were 35% and 42%, with a median of 22 months and 43 months, respectively. Multivariate analysis identified male gender (P - 0.03, hazard ratio [HR] - 0.46, 95% confidence interval [CI] - 0.23\u20130.92), baseline metastatic disease (P - 0.01, HR - 2.98, 95% CI - 1.27\u20136.98) and Grade III tumors (P - 0.02, HR - 1.84, 95% CI - 1.08\u20133.13) as factors associated with poor EFS, whereas baseline metastatic disease (P &lt; 0.001, HR - 5.45, 95% CI - 2.31\u201312.87) and unresectability (P - 0.01, HR - 2.72, 95% CI - 1.27\u20135.83) were associated with poor OS. Conclusion: This is a single-institutional study of patients with abdominopelvic sarcomas where gender was identified as a new factor affecting survival apart from baseline presentation, histologic grade, and surgical resection.<\/jats:p>","DOI":"10.4103\/0971-5851.180134","type":"journal-article","created":{"date-parts":[[2016,4,12]],"date-time":"2016-04-12T09:25:22Z","timestamp":1460453122000},"page":"100-105","source":"Crossref","is-referenced-by-count":3,"title":["Nonrhabdomyosarcomatous abdominopelvic sarcomas: Analysis of prognostic factors"],"prefix":"10.1055","volume":"37","author":[{"given":"Nida","family":"Iqbal","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nootan K","family":"Shukla","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. V. S.","family":"Deo","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Agarwala","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meher C","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Pathology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameer","family":"Bakhshi","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,7,12]]},"container-title":["Indian Journal of Medical and Paediatric Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/0971-5851.180134.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T04:42:41Z","timestamp":1717735361000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.4103\/0971-5851.180134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":0,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2021,7,12]]},"published-print":{"date-parts":[[2016,4]]}},"URL":"https:\/\/doi.org\/10.4103\/0971-5851.180134","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0971-5851","0975-2129"],"issn-type":[{"value":"0971-5851","type":"print"},{"value":"0975-2129","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4]]}}}