{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T19:30:30Z","timestamp":1792006230021,"version":"4.4.0"},"reference-count":17,"publisher":"Scientific Scholar","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec>\n            <jats:title>Background &amp; objectives:<\/jats:title>\n            <jats:p>Various conventional methods such as gaseous, vapour and misting systems, fogging, manual spray and wipe techniques employing a number of chemical agents are used for decontamination of enclosed spaces. Among all these methods, use of aerosolized formaldehyde is the most preferred method due to cost-effectiveness and practical aspects. However, being extremely corrosive in nature generating very irritating fumes and difficulty in maintaining a high level of gas concentration, many laboratories prefer the vaporization of hydrogen peroxide (H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub>) as an alternative. We present here the results of using H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> vapour in combination with plasma irradiation for quick decontamination of closed chambers.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>The present study describes a decontamination method, using plasma irradiation in combination with H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> (5%). Effect of plasma irradiation and H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> on the viability of bacterial spores (<jats:italic toggle=\"yes\">Bacillus subtilis<\/jats:italic>), Chikungunya and Kyasanur Forest Disease viruses was assessed.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>Data suggest that with the combination of H<jats:sub>2<\/jats:sub>O<jats:sub>2<\/jats:sub> vapour and plasma irradiation, within short time (three minutes), decontamination of surfaces and space volume could be achieved. Although it showed damage of spores present on the strips, it did not show any penetration power.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Interpretation &amp; conclusions:<\/jats:title>\n            <jats:p>The results were encouraging, and this method was found to be efficient for achieving surface sterilization in a short time. This application may be useful in laboratories and industries particularly, those working on clean facility concept following good laboratory and manufacturing practices.<\/jats:p>\n          <\/jats:sec>","DOI":"10.4103\/0971-5916.195039","type":"journal-article","created":{"date-parts":[[2016,12,12]],"date-time":"2016-12-12T09:44:36Z","timestamp":1481535876000},"page":"245-249","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Use of hydrogen peroxide vapour &amp; plasma irradiation in combination for quick decontamination of closed chambers"],"prefix":"10.25259","volume":"144","author":[{"given":"Devendra T.","family":"Mourya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamish C.","family":"Shahani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pragya D.","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradip V.","family":"Barde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","reference":[{"key":"R2-13-20241212","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/153567601201700107","article-title":"Gaseous decontamination methods in high-containment laboratories","volume":"17","author":"Gordon","year":"2012","journal-title":"Appl Biosafety"},{"key":"R4-13-20241212","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jhin.2005.07.020","article-title":"Decontamination of rooms, medical equipment and ambulances using an aerosol of hydrogen peroxide disinfectant","volume":"62","author":"Andersen","year":"2006","journal-title":"J Hosp 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Photobiol"},{"key":"R12-13-20241212","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/j.1472-765X.2007.02209.x","article-title":"Bacterial endospore inactivation caused by outgassing of vapourous hydrogen peroxide from polymethyl methacrylate (Plexiglas\u00ae)","volume":"45","author":"Baron","year":"2007","journal-title":"Lett Appl Microbiol"},{"key":"R13-13-20241212","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.jhin.2007.08.020","article-title":"Prion inactivation using a new gaseous hydrogen peroxide sterilisation process","volume":"67","author":"Fichet","year":"2007","journal-title":"J Hosp Infect"},{"key":"R14-13-20241212","doi-asserted-by":"crossref","first-page":"2955","DOI":"10.1128\/JCM.00250-08","article-title":"Efficacy of dry mist of hydrogen peroxide (DMHP) against Mycobacterium tuberculosis and use of DMHP for routine decontamination of biosafety level 3 laboratories","volume":"46","author":"Grare","year":"2008","journal-title":"J Clin Microbiol"},{"key":"R15-13-20241212","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jhin.2007.07.019","article-title":"Assessing the biological efficacy and rate of recontamination following hydrogen peroxide vapour decontamination","volume":"67","author":"Otter","year":"2007","journal-title":"J Hosp Infect"},{"key":"R16-13-20241212","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1111\/j.1365-2672.2005.02686.x","article-title":"Decontamination assessment of Bacillus anthracis, Bacillus subtilis, and Geobacillus stearothermophilus spores on indoor surfaces using a hydrogen peroxide gas generator","volume":"99","author":"Rogers","year":"2005","journal-title":"J Appl Microbiol"},{"key":"R17-13-20241212","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1128\/JCM.01797-06","article-title":"Use of hydrogen peroxide vapor for deactivation of Mycobacterium tuberculosis in a biological safety cabinet and a room","volume":"45","author":"Hall","year":"2007","journal-title":"J Clin Microbiol"},{"key":"R18-13-20241212","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-5173(01)00752-9","article-title":"Low-temperature sterilization using gas plasmas: a review of the experiments and an analysis of the inactivation mechanisms","volume":"226","author":"Moisan","year":"2001","journal-title":"Int J Pharm"},{"key":"R19-13-20241212","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1109\/TPS.2002.804220","article-title":"Nonthermal decontamination of biological media by atmospheric-pressure plasmas: review, analysis, and prospects","volume":"30","author":"Laroussi","year":"2003","journal-title":"IEEE Trans Plasma Sci"},{"key":"R20-13-20241212","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1615\/PlasmaMed.2014011720","article-title":"Comparative study on the use of different metal electrodes in low-pressure glow discharge plasma 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plasma","volume":"20","author":"Wintenberg","year":"1998","journal-title":"J Ind Microbiol Biotechnol"}],"container-title":["Indian Journal of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/02223309-201644020-00013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T22:58:08Z","timestamp":1751497088000},"score":1,"resource":{"primary":{"URL":"https:\/\/ijmr.org.in\/use-of-hydrogen-peroxide-vapour-plasma-irradiation-in-combination-for-quick-decontamination-of-closed-chambers\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.4103\/0971-5916.195039","relation":{},"ISSN":["0971-5916"],"issn-type":[{"value":"0971-5916","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]}}}