{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:37:12Z","timestamp":1787071032991,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Introducer needle tip is not clearly visible during the real-time ultrasound (US)-guided central vein cannulation (CVC). Blind tip leads to mechanical complications. This study was designed to evaluate whether real-time US-guided CVC with a marked introducer needle is superior to the existing unmarked needle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>Sixty-two critically ill patients aged 18\u201360 years of either sex were included in the study. The patients were randomized into two groups based on whether a marked or unmarked introducer needle was used. Both groups underwent real-time US-guided CVC by a single experienced operator. Aseptically, introducer needle was indented with markings spaced 0.5 cm (single marking) and every 1 cm (double marking). This needle was used in the marked group. Approximate depths (centimeter) of the anterior and posterior wall of the internal jugular vein, anterior wall of the internal carotid artery, and lung pleura were appreciated from the midpoint of the probe in short-axis view at the level of the cricoid cartilage. Access time (seconds) was recorded using a stopwatch. A number of attempts and complications such as arterial puncture, hematoma, and pneumothorax of either procedure were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Both marked needle and unmarked needle groups were comparable with regard to age, gender, severity scores, platelet counts, prothrombin time, and distance from the midpoint of the probe to the vein, artery, and pleura and skin-to-guide wire insertion access time. However, an average number of attempts (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.03) and complications such as hematoma were significantly lower (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.02) with the marked introducer needle group. Pneumothorax was not reported in any of the groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our study supports the idea that marked introducer needle can further reduce the iatrogenic complications of US-guided CVC.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0971-9784.191563","type":"journal-article","created":{"date-parts":[[2016,10,7]],"date-time":"2016-10-07T02:21:40Z","timestamp":1475806900000},"page":"621-625","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Comparison between marked versus unmarked introducer needle in real-time ultrasound-guided central vein cannulation: A prospective randomized study"],"prefix":"10.4103","volume":"19","author":[{"given":"Tanmoy","family":"Ghatak","sequence":"first","affiliation":[{"name":"Department of Anesthesia and Critical Care Medicine, IIMS and R, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ratender Kumar","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, SGPGIMS, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvind Kumar","family":"Baronia","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, SGPGIMS, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250921","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1097\/CCM.0b013e318218a1ae","article-title":"Real-time ultrasound-guided subclavian vein cannulation versus the landmark method in critical care patients: A prospective randomized study","volume":"39","author":"Fragou","year":"2011","journal-title":"Crit Care Med"},{"key":"R2-20250921","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1136\/bmj.327.7411.361","article-title":"Ultrasonic locating devices for central venous cannulation: Meta-analysis","volume":"327","author":"Hind","year":"2003","journal-title":"BMJ"},{"key":"R3-20250921","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.annemergmed.2006.01.011","article-title":"Real-time ultrasonographically-guided internal jugular vein catheterization in the emergency department increases success rates and reduces complications: A randomized, prospective study","volume":"48","author":"Leung","year":"2006","journal-title":"Ann Emerg Med"},{"key":"R4-20250921","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.clineuro.2012.08.025","article-title":"Comparison of catheter-related large vein thrombosis in centrally inserted versus peripherally inserted central venous lines in the neurological intensive care unit","volume":"115","author":"Wilson","year":"2013","journal-title":"Clin Neurol Neurosurg"},{"key":"R5-20250921","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1097\/CCM.0b013e3181a067d4","article-title":"An unseen danger: Frequency of posterior vessel wall penetration by needles during attempts to place internal jugular vein central catheters using ultrasound guidance","volume":"37","author":"Blaivas","year":"2009","journal-title":"Crit Care Med"},{"key":"R6-20250921","doi-asserted-by":"crossref","first-page":"R162","DOI":"10.1186\/cc5101","article-title":"Real-time ultrasound-guided catheterisation of the internal jugular vein: A prospective comparison with the landmark technique in critical care patients","volume":"10","author":"Karakitsos","year":"2006","journal-title":"Crit Care"},{"key":"R7-20250921","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1097\/00003246-199206000-00025","article-title":"Members of the American College of Chest Physicians\/Society of Critical Care Medicine Consensus Conference Committee. American College of Chest Physicians\/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis","volume":"20","year":"1992","journal-title":"Crit Care Med"},{"key":"R8-20250921","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1097\/CCM.0b013e3181a9f694","article-title":"Before we go too far: Ultrasound-guided central catheter placement","volume":"37","author":"Levitov","year":"2009","journal-title":"Crit Care Med"},{"key":"R9-20250921","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/bja\/aes381","article-title":"Three-step method for ultrasound-guided central vein catheterization","volume":"110","author":"Tokumine","year":"2013","journal-title":"Br J Anaesth"},{"key":"R10-20250921","first-page":"617149","article-title":"Optimization of cannula visibility during ultrasound-guided subclavian vein catheterization, via a longitudinal approach, by implementing echogenic technology","author":"Stefanidis","year":"2012","journal-title":"Crit Care Res Pract 2012"},{"key":"R11-20250921","doi-asserted-by":"crossref","first-page":"296","DOI":"10.4103\/0971-9784.119185","article-title":"Use of optimized ultrasound axis along with marked introducer needle to prevent mechanical complications of internal jugular vein catheterization","volume":"16","author":"Ghatak","year":"2013","journal-title":"Ann Card Anaesth"}],"container-title":["Annals of Cardiac Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00660469-201619040-00011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:40:34Z","timestamp":1787067634000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00660469-201619040-00011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.4103\/0971-9784.191563","relation":{},"ISSN":["0971-9784","0974-5181"],"issn-type":[{"value":"0971-9784","type":"print"},{"value":"0974-5181","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"2016-02-20","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-07-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}