{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:32:23Z","timestamp":1787776343523,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,4]]},"abstract":"\n Context:<\/jats:title>\n Analgesia and sedation are required for the comfort of patient and the cardiologist during balloon mitral valvotomy.<\/jats:p>\n <\/jats:sec>\n \n Aims:<\/jats:title>\n In this study, efficacy of analgesia, sedation, and patient satisfaction with sufentanil was compared with fentanyl.<\/jats:p>\n <\/jats:sec>\n \n Settings and Design:<\/jats:title>\n Single-centered, prospective single-blind study of sixty patients.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n Patients between 15 and 45 years of rheumatic mitral stenosis with valve area of 0.8\u20131 cm\n 2<\/jats:sup>\n undergoing elective balloon mitral valvotomy, randomly divided to receive bolus injection fentanyl 1 mcg\/kg (Group 1,\n n<\/jats:italic>\n = 30) followed by infusion at 1 mcg\/kg\/h or bolus of injection sufentanil 0.1 mcg\/kg (Group 2,\n n<\/jats:italic>\n = 30) followed by continuous infusion at 0.1 mcg\/h. Both the groups received injection midazolam bolus 0.02 mg\/kg followed by infusion at 15 mcg\/kg\/h. Pain intensity (by visual analog score [VAS]), level of sedation (by Ramsay sedation scale), overall patient and operator's satisfaction, effect on cardiorespiratory parameters, and discharge score (by modified Aldrete score) were assessed.\n <\/jats:p>\n <\/jats:sec>\n \n Statistical Analysis Used:<\/jats:title>\n \n Statistical analysis used Student's unpaired\n t<\/jats:italic>\n -test and Chi-square test.\n P<\/jats:italic>\n < 0.05 was considered statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Mean number of bolus doses in fentanyl group was 0.9 versus 0.13 in sufentanil group (\n P<\/jats:italic>\n < 0.01). The mean value of mean blood pressure in fentanyl group was 83.52 mmHg versus 88 mmHg in sufentanil group (\n P<\/jats:italic>\n < 0.05), but the value was within normal range in both the groups. The mean VAS \u2013 patient's opinion in fentanyl group was 8.97 versus 9.53 in sufentanil group (\n P<\/jats:italic>\n < 0.05). Mean discharge score in fentanyl group was 17.87 versus 18.23 in sufentanil group (\n P<\/jats:italic>\n < 0.05). No statistically significant difference was found with respect to heart rate, respiratory rate, oxygen saturation, PaCO\n 2<\/jats:sub>\n values, and anxiety scores.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Sufentanil was found to be better with respect to analgesia, patient satisfaction, and recovery however not cost-effective for continuous infusion technique.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/0971-9784.203930","type":"journal-article","created":{"date-parts":[[2017,4,6]],"date-time":"2017-04-06T11:15:08Z","timestamp":1491477308000},"page":"163-168","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Conscious Sedation for Balloon Mitral Valvotomy: A Comparison of Fentanyl versus Sufentanil"],"prefix":"10.4103","volume":"20","author":[{"given":"Shailendra Deochandra","family":"Modak","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Lokmanya Tilak Municipal Medical and General Hospital, Sion, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepa G","family":"Kane","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Seth G. 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