{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T15:42:04Z","timestamp":1786635724073,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Indian Soc Periodontol"],"published-print":{"date-parts":[[2009]]},"DOI":"10.4103\/0972-124x.60224","type":"journal-article","created":{"date-parts":[[2010,3,20]],"date-time":"2010-03-20T01:13:50Z","timestamp":1269047630000},"page":"126","source":"Crossref","is-referenced-by-count":13,"title":["Evaluation of two local drug delivery systems as adjuncts to mechanotherapy as compared to mechanotherapy alone in management of chronic periodontitis: A clinical, microbiological, and molecular study"],"prefix":"10.4103","volume":"13","author":[{"given":"Sangeeta","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subrata","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SK","family":"Chumber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0972-124X.60224-1","doi-asserted-by":"crossref","unstructured":"Sanz M, Lau L, Herrera D, Morillo JM, Silva A. Methods of detection of Actinobacillus actinomyctemcomitans, Porphyromonas gingivalis, Tannerella forsythensis in periodontal microbiology with special emphasis on advanced molecular techniques: A review. J Clin Periodontol 2004;1034-47.","DOI":"10.1111\/j.1600-051X.2004.00609.x"},{"key":"key-10.4103\/0972-124X.60224-2","first-page":"125","volume-title":"The role of controlled drug delivery for periodontitis","author":"AAP","year":"2000","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.60224-3","first-page":"305","volume-title":"Chemical treatment of periodontitis: Local delivery of antimicrobials","author":"Killoy","year":"1998","journal-title":"Int Dent J"},{"key":"key-10.4103\/0972-124X.60224-4","first-page":"509","volume-title":"Improved low cost selective culture medium for Actinobacillus actinomycetemcomitans","author":"Alsina","year":"2001","journal-title":"J Clin Microbiol"},{"key":"key-10.4103\/0972-124X.60224-5","first-page":"1","volume-title":"Structure of micro flora associated with periodontal disease and health in man: A light and electron microscopic study","author":"Listgarten","year":"1976","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.60224-6","first-page":"322","volume-title":"Bacterial etiology of destructive periodontal disease: Current concepts","author":"Socransky","year":"1992","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.60224-7","first-page":"59","volume-title":"Rapid detection of Actinobacillus actinomyctemcomitans, Prevotella intermedia and Porphyromonas gingivalis by multiplex PCR","author":"Garcia","year":"1998","journal-title":"J Periodont Res"},{"key":"key-10.4103\/0972-124X.60224-8","first-page":"2362","volume-title":"Quantitative Real time PCR for Porphyromonas gingivalis and total bacteria","author":"Lyons","year":"2000","journal-title":"J Clin Microbiol"},{"key":"key-10.4103\/0972-124X.60224-9","first-page":"1796","volume-title":"Simultaneous detection of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis by rapid PCR method","author":"Wahlfors","year":"1995","journal-title":"J Dent Res"},{"key":"key-10.4103\/0972-124X.60224-10","first-page":"265","volume-title":"Periodontal disease treatment by local drug delivery","author":"Goodson","year":"1985","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.60224-11","first-page":"693","volume-title":"The development and in vitro evaluation of acrylic strips and dialysis tubing for local drug delivery","author":"Addy","year":"1982","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.60224-12","first-page":"146","volume-title":"Topical metronidazole as an adjunct to sub gingival debridement in the treatment of chronic periodontitis","author":"Hitzig","year":"1994","journal-title":"J Clin Periodontitis"},{"key":"key-10.4103\/0972-124X.60224-13","first-page":"613","volume-title":"Effects of combined topical metronidazole and mechanical treatment on sub gingival flora in deep Periodontal pockets in cuspids and bicuspids","author":"Hitzig","year":"1997","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.60224-14","first-page":"124","volume-title":"The development and clinical use of acrylic strips containing antimicrobial agents in the management of chronic periodontitis","author":"Addy","year":"1985","journal-title":"Int Dent J"},{"key":"key-10.4103\/0972-124X.60224-15","first-page":"723","volume-title":"Clinical responses to sub gingival application of a metronidazole 25% dental gel compared to the effect of sub gingival scaling in adult periodontitis","author":"Ainamo","year":"1992","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0972-124X.60224-16","doi-asserted-by":"crossref","unstructured":"Klinge B, Attstrom R, Karring T, Kisch J, Lewin B, Stolzke K. Three regimens of topical metronidazole compared with sub gingival scaling on periodontal pathology in adults. J Clin Periodontol 1992; 708-714.","DOI":"10.1111\/j.1600-051X.1992.tb02533.x"},{"key":"key-10.4103\/0972-124X.60224-17","first-page":"715","volume-title":"Comparative clinical and microbiological effects of topical sub gingival application of metronidazole 25% dental gel and scaling in treatment of adult periodontitis","author":"Pedrazzoli","year":"1992","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0972-124X.60224-18","doi-asserted-by":"crossref","unstructured":"Rudhart A, Purucker P, Kage A, Hopfenm\u00fcller W, Bernimoulin JP. Local metronidazole application in maintenance patients. Clinical and microbiological evaluation. J Periodontol 1998;69:1148-54.","DOI":"10.1902\/jop.1998.69.10.1148"},{"key":"key-10.4103\/0972-124X.60224-19","first-page":"343","volume-title":"Effect of root debridement on elimination of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis from Periodontal pockets","author":"Renvert","year":"1990","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0972-124X.60224-20","first-page":"437","volume-title":"Effect of non surgical periodontal treatment on clinical parameters and the numbers of Porphyromonas gingivalis, Prevotella intermedia and Actinobacillus actinomycetemcomitans at adult periodontitis sites","author":"Doungudomdacha","year":"2001","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0972-124X.60224-21","first-page":"287","volume-title":"Therapeutic effects of combined treatment using tetracycline immobilized collagen film and root planing in periodontal furcation pockets","author":"Minabe","year":"1991","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0972-124X.60224-22","first-page":"700","volume-title":"Evaluation of periodontal treatments using controlled release tetracycline fibers: Microbiological response","author":"Lowenguth","year":"1995","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.60224-23","first-page":"715","volume-title":"Comparative clinical and microbiological effects of topical sub gingival application of metronidazole 25% dental gel and scaling in treatment of adult periodontitis","author":"Pedrazzoli","year":"1992","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0972-124X.60224-24","first-page":"671","volume-title":"Dark-field microscopic monitoring of sub gingival bacteria during periodontal therapy","author":"Singletary","year":"1982","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.60224-25","first-page":"579","volume-title":"Recolonization of the sub gingival micro flora following scaling and root planing in human periodontitis","author":"Sbordone","year":"1990","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.60224-26","first-page":"598","volume-title":"Effect of surgical and non surgical periodontal treatment on periodontal status and sub gingival micro biota","author":"Pedrazzoli","year":"1991","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0972-124X.60224-27","first-page":"906","volume-title":"Topographic distribution of black pigmented anaerobes before and after Periodontal treatment by local drug delivery of tetracycline","author":"Mombelli","year":"1996","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0972-124X.60224-28","first-page":"102","volume-title":"Longitudinal study of prognostic factors in established periodontitis patients","author":"Machtei","year":"1997","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0972-124X.60224-29","first-page":"3504","volume-title":"Improved multiplex PCR using conserved and species specific 16S rRNA gene primers for simultaneous detection of Actinobacillus actinomycetemcomitans, Bacteroides forsythus and Porphyromonas gingivalis","author":"Tran","year":"1999","journal-title":"J Clin Microbiol"},{"key":"key-10.4103\/0972-124X.60224-30","first-page":"59","volume-title":"Rapid detection of Actinobacillus actinomyctemcomitans, Prevotella intermedia and Porphyromonas gingivalis by multiplex PCR","author":"Garcia","year":"1998","journal-title":"J Periodont Res"}],"container-title":["Journal of Indian Society of Periodontology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T14:49:27Z","timestamp":1786632567000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0972-124X.60224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009]]}},"alternative-id":["60224"],"URL":"https:\/\/doi.org\/10.4103\/0972-124x.60224","relation":{},"ISSN":["0972-124X"],"issn-type":[{"value":"0972-124X","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]}}}