{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T15:56:30Z","timestamp":1786636590657,"version":"build-2736575974"},"reference-count":43,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Indian Soc Periodontol"],"published-print":{"date-parts":[[2010]]},"DOI":"10.4103\/0972-124x.75908","type":"journal-article","created":{"date-parts":[[2011,1,20]],"date-time":"2011-01-20T04:11:40Z","timestamp":1295496700000},"page":"148","source":"Crossref","is-referenced-by-count":74,"title":["The link between periodontal disease and cardiovascular disease: How far we have come in last two decades ?"],"prefix":"10.4103","volume":"14","author":[{"given":"Prasad","family":"Dhadse","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepti","family":"Gattani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0972-124X.75908-1","first-page":"89","volume-title":"Life time risk of developing coronary heart disease","author":"Lloyd-Jones","year":"1999","journal-title":"Lancet"},{"key":"key-10.4103\/0972-124X.75908-2","first-page":"197","volume-title":"Periodontal diseases and cardiovascular events: Meta-analysis of observational studies","author":"Blaizot","year":"2009","journal-title":"Int Dent J"},{"key":"key-10.4103\/0972-124X.75908-3","unstructured":"World health organization. World health report, Changing History; 2004."},{"key":"key-10.4103\/0972-124X.75908-4","first-page":"712","volume-title":"Prevalence and risk factors of prehypertension and hypertension in an affluent north Indian population","author":"Yadav","year":"2008","journal-title":"Indian J Med Res","ISSN":"https:\/\/id.crossref.org\/issn\/0971-5916","issn-type":"print"},{"key":"key-10.4103\/0972-124X.75908-5","first-page":"221","volume-title":"Oral hygiene, gingivitis and periodontal breakdown in adult Tanzanians","author":"Baehum","year":"1986","journal-title":"J Periodontal Res"},{"key":"key-10.4103\/0972-124X.75908-6","first-page":"NIDR; 1987","volume-title":"S","author":"U","year":"87-2","journal-title":"Public health service, National Institute of Dental Research; Oral Health of United States Adults; National Findings, NIH publ no"},{"key":"key-10.4103\/0972-124X.75908-7","first-page":"14S","volume-title":"Periodontal disease and cardiovascular disease: Epidemiology and possible mechanisms","author":"Genco","year":"2002","journal-title":"J Am Dent Assoc"},{"key":"key-10.4103\/0972-124X.75908-8","first-page":"7S","volume-title":"Infections and their role in atherosclerotic vascular disease","author":"Fong","year":"2002","journal-title":"J Am Dent Assoc"},{"key":"key-10.4103\/0972-124X.75908-9","unstructured":"Rose LF, Genco RJ, Cohen DW, Mealey BL. Periodontal Medicine. Hamilton: B.C.Decker Inc; 2000."},{"key":"key-10.4103\/0972-124X.75908-10","first-page":"483","volume-title":"Ischemic heart disease: Dental management considerations","author":"Hupp","year":"2006","journal-title":"Dent Clin North Am"},{"key":"key-10.4103\/0972-124X.75908-11","first-page":"142","volume-title":"Periodontal diseases\u2032 contributions to cardiovascular disease: An overview of potential mechanisms","author":"Kinane","year":"1998","journal-title":"Ann Periodontol"},{"key":"key-10.4103\/0972-124X.75908-12","first-page":"9","volume-title":"The association between periodontal diseases and cardiovascular diseases: A state-of-the-science review","author":"Beck","year":"2001","journal-title":"Ann Periodontol"},{"key":"key-10.4103\/0972-124X.75908-13","doi-asserted-by":"crossref","unstructured":"Kalayoglu MV, Byrne GI. A chlamydia pneumoniae component that induces macrophage foam cells formation in chlamydial lipopolysaccharides. Infect Immun 1998;66;5067-72.","DOI":"10.1128\/IAI.66.11.5067-5072.1998"},{"key":"key-10.4103\/0972-124X.75908-14","unstructured":"Falk E, Shah PK, Fuster V. Pathogenesis of plaque disruption. In: Fuster V, RossR, Topol EJ, editors. Atherosclerosis and coronary artery disease. Vol. 2. Philadelphia: Lippincott-Raven; 1996. p. 492-510."},{"key":"key-10.4103\/0972-124X.75908-15","first-page":"37S","volume-title":"Oral care for patients with cardiovascular disease and stroke","author":"Rose","year":"2002","journal-title":"J Am Dent Assoc"},{"key":"key-10.4103\/0972-124X.75908-16","first-page":"115","volume-title":"Atherosclerosis: An inflammatory disease","author":"Ross","year":"1999","journal-title":"N Engl J Med"},{"key":"key-10.4103\/0972-124X.75908-17","doi-asserted-by":"crossref","unstructured":"Danesh J, Collins R, Peto R. Chronic infections and coronary heart disease: Is there a link ? Lancet 1997;50;430-6.","DOI":"10.1016\/S0140-6736(97)03079-1"},{"key":"key-10.4103\/0972-124X.75908-18","first-page":"1138","volume-title":"Effects oral flora on platelets: Possible consequences in cardiovascular disease","author":"Herzberg","year":"1996","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.75908-19","first-page":"1554","volume-title":"Identification of periodontal pathogens in atheromatous plaques","author":"Haraszthy","year":"2007","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.75908-20","first-page":"41","volume-title":"Role of periodontal bacteria in cardiovascular disease","author":"Kuramitsu","year":"2001","journal-title":"Ann periodontal"},{"key":"key-10.4103\/0972-124X.75908-21","first-page":"779","volume-title":"Association between dental health and acute myocardial infarction","author":"Mattila","year":"1989","journal-title":"BMJ"},{"key":"key-10.4103\/0972-124X.75908-22","first-page":"588","volume-title":"Dental infections and the risk of new coronary events: Prospective study of patients with documented coronary artery disease","author":"Mattila","year":"1995","journal-title":"Clin Infect Dis"},{"key":"key-10.4103\/0972-124X.75908-23","first-page":"688","volume-title":"Dental disease and risk of coronary heart disease and mortality","author":"DeStefano","year":"1993","journal-title":"BMJ"},{"key":"key-10.4103\/0972-124X.75908-24","first-page":"1123","volume-title":"Periodontal disease and cardiovascular disease","author":"Beck","year":"1996","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.75908-25","first-page":"1631","volume-title":"Poor oral health and coronary heart disease","author":"Joshipura","year":"1996","journal-title":"J Dent Res"},{"key":"key-10.4103\/0972-124X.75908-26","first-page":"3158","volume-title":"Periodontal disease is a predictor of cardiovascular disease in a Native American population","author":"Genco","year":"1997","journal-title":"J Dent Res"},{"key":"key-10.4103\/0972-124X.75908-27","first-page":"1777","volume-title":"Association between extent of periodontal attachment loss and self reported history of heart attack: An analysis of NHANES III data","author":"Arbes","year":"1999","journal-title":"J Dent Res"},{"key":"key-10.4103\/0972-124X.75908-28","first-page":"457","volume-title":"Periodontal microflora related to the risk for myocardial infarction; a case control study","author":"Genco","year":"1999","journal-title":"J Dent Res"},{"key":"key-10.4103\/0972-124X.75908-29","first-page":"7","volume-title":"Periodontal disease aand risk of fatal coronary heart and cerebrovascular diseases","author":"Morrison","year":"1996","journal-title":"J Cardiovasc Risk"},{"key":"key-10.4103\/0972-124X.75908-30","first-page":"2749","volume-title":"Periodontal disease and risk of cerebrovascular disease: The first national health and nutrition examination survey and its follow-up study","author":"Wu","year":"2000","journal-title":"Arch Intern Med"},{"key":"key-10.4103\/0972-124X.75908-31","first-page":"1406","volume-title":"Periodontal disease and coronary heart disease risk","author":"Hujoel","year":"2000","journal-title":"JAMA"},{"key":"key-10.4103\/0972-124X.75908-32","doi-asserted-by":"crossref","unstructured":"Howell TH, Ridker PM, Ajani UA, Hennekens CH, Christen WG. Periodontal disease and risk of subsequent cardiovascular disease in U.S. male physicians. J Am Coll Cardiol 2001;37:445-50.","DOI":"10.1016\/S0735-1097(00)01130-X"},{"key":"key-10.4103\/0972-124X.75908-33","first-page":"559","volume-title":"Meta-analysis of periodontal disease and risk of coronary heart disease and stroke","author":"Janket","year":"2003","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"key-10.4103\/0972-124X.75908-34","first-page":"38","volume-title":"Associations between periodontal disease and risk for atherosclerosis, cardiovascular disease and stroke: A systematic review","author":"Scannapieco","year":"2003","journal-title":"Ann Periodontol"},{"key":"key-10.4103\/0972-124X.75908-35","first-page":"1046","volume-title":"Periodontal diseases and the risk of coronary heart and cerebrovascular diseases: A meta-analysis","author":"Khader","year":"2004","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.75908-36","first-page":"2008","volume-title":"Meta-analysis of observational studies in epidemiology: A proposal for reporting Meta- analysis of observational studies in epidemiology (MOOSE) group","author":"Stroup","year":"2000","journal-title":"JAMA"},{"key":"key-10.4103\/0972-124X.75908-37","first-page":"1221","volume-title":"Relation between periodontal infection and C- reactive protein","author":"Noack","year":"2001","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.75908-38","first-page":"97","volume-title":"C- reactive protein localizes with complement in human heart during acute myocardial infarction","author":"Lagrand","year":"1997","journal-title":"Circulation"},{"key":"key-10.4103\/0972-124X.75908-39","first-page":"c2451","volume-title":"Tooth brushing, inflammation and risk of cardiovascular disease: Results from Scottish Health Survey","author":"de","year":"2010","journal-title":"BMJ"},{"key":"key-10.4103\/0972-124X.75908-40","first-page":"347","volume-title":"Systemic acute phase reactants, C-reactive protein and haptoglobin in adult periodontitis","author":"Ebersole","year":"1997","journal-title":"Clin Exp Immunol"},{"key":"key-10.4103\/0972-124X.75908-41","first-page":"756","volume-title":"Age, dental infections and coronary heart disease","author":"Mattila","year":"2000","journal-title":"J Dent Res"},{"key":"key-10.4103\/0972-124X.75908-42","first-page":"686","volume-title":"Population distribution of high sensitivity C- Reactive protein among U.S Men: Finding from National Health and nutrition Examination survey 1999 - 2000","author":"Ford","year":"2003","journal-title":"Clin Chem"},{"key":"key-10.4103\/0972-124X.75908-43","first-page":"222","volume-title":"Inadequate adjustment for smoking in periodontitis: Systemic disease associations","author":"Spiekerman","year":"2001","journal-title":"Ann Periodontol"}],"container-title":["Journal of Indian Society of Periodontology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T14:58:44Z","timestamp":1786633124000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0972-124X.75908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010]]}},"alternative-id":["75908"],"URL":"https:\/\/doi.org\/10.4103\/0972-124x.75908","relation":{},"ISSN":["0972-124X"],"issn-type":[{"value":"0972-124X","type":"print"}],"subject":[],"published":{"date-parts":[[2010]]}}}