{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:27:41Z","timestamp":1791491261056,"version":"4.3.4"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Orthostatic tremor (OT), is usually a disease of old age and is characterized by quivering movements of the legs during quiet standing or in the state of isometric contraction in the lower limbs. This is relieved on walking or on lying down. It is diagnosed by surface electromyography, particularly over the quadriceps femoris muscles which shows a distinctive frequency of 13 to 18 Hz on standing. Some investigators consider it as a variant of essential tremor (ET) and the two conditions often co-exist. The disease is usually non-familial. Two brothers presented with tremor in the lower limbs on standing and on the outstretched hands without any family history. Subsequently, they were proved to be suffering from OT and ET by clinical examination and surface EMG. Simultaneous occurrence of OT and ET in two young brothers without any family history in the previous generation has not been described before and they also appeared at a much earlier age than what is described in the literature.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0972-2327.112497","type":"journal-article","created":{"date-parts":[[2013,5,24]],"date-time":"2013-05-24T04:37:35Z","timestamp":1369370255000},"page":"276-278","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Familial orthostatic tremor and essential tremor in two young brothers"],"prefix":"10.4103","volume":"16","author":[{"given":"Kalyan B","family":"Bhattacharyya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-35-20260109","first-page":"450","article-title":"Su di un singolare disturbodeura stazione eretta (osservazione di tri casi)","volume":"96","author":"Pazzaglia","year":"1970","journal-title":"Riv Freniatr"},{"key":"R2-35-20260109","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1001\/archneur.1984.04050190086020","article-title":"Orthostatic tremor","volume":"41","author":"Heilman","year":"1984","journal-title":"Arch Neurol"},{"key":"R3-35-20260109","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/mds.10324","article-title":"Primary orthostatic tremor is an exaggeration of a physiological response to instability","volume":"18","author":"Sharott","year":"2003","journal-title":"Mov Disord"},{"key":"R4-35-20260109","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1212\/WNL.36.9.1241","article-title":"Orthostatic tremor in familial-essential tremor","volume":"36","author":"Wee","year":"1986","journal-title":"Neurology"},{"key":"R5-35-20260109","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/ana.410340115","article-title":"A positron emission tomography study of essential tremor: Evidence for over activity of cerebellar connections","volume":"34","author":"Jenkins","year":"1993","journal-title":"Ann Neurol"},{"key":"R6-35-20260109","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1001\/archneur.1995.00540270095025","article-title":"A positron emission tomography study of cerebral activation associated with essential and writing tremor","volume":"52","author":"Wills","year":"1995","journal-title":"Arch Neurol"},{"key":"R7-35-20260109","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1001\/archneur.1986.00520060048016","article-title":"The physiology of orthostatic tremor","volume":"43","author":"Thompson","year":"1986","journal-title":"Arch Neurol"},{"key":"R8-35-20260109","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1002\/mds.20132","article-title":"Natural history and syndromic associations of orthostatic tremor: A review of 41 patients","volume":"19","author":"Gerschlager","year":"2004","journal-title":"Mov Disord"},{"key":"R9-35-20260109","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1002\/mds.20588","article-title":"Clinical and neurophysiologic spectrum of orthostatic tremor: Case series of 26 subjects","volume":"20","author":"Piboolnurak","year":"2005","journal-title":"Mov Disord"},{"key":"R10-35-20260109","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/mds.870131303","article-title":"Consensus statement of the movement disorder society on tremor. 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