{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T15:31:53Z","timestamp":1786635113758,"version":"build-2736575974"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Indian Acad Neurol"],"published-print":{"date-parts":[[2008]]},"DOI":"10.4103\/0972-2327.42941","type":"journal-article","created":{"date-parts":[[2009,2,19]],"date-time":"2009-02-19T06:41:56Z","timestamp":1235025716000},"page":"190","source":"Crossref","is-referenced-by-count":5,"title":["Sotos syndrome: An interesting disorder with gigantism"],"prefix":"10.4103","volume":"11","author":[{"given":"A","family":"Nalini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arundhati","family":"Biswas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0972-2327.42941-1","doi-asserted-by":"crossref","unstructured":"Sotos JF, Dodge PR, Muirhead D, Crawford JD, Talbot NB. Cerebral gigantism in childhood. A syndrome of excessively rapid growth with acromegalic features and a non progressive neurologic disorder. N Engl J Med 1964;271:109.","DOI":"10.1056\/NEJM196407162710301"},{"key":"key-10.4103\/0972-2327.42941-2","first-page":"243","volume-title":"Sotos syndrome-autosomal dominant inheritance substantiated","author":"Winship","year":"1985","journal-title":"Clin Genet"},{"key":"key-10.4103\/0972-2327.42941-3","first-page":"900","volume-title":"Cerebral gigantism: Endocrinological and clinical observations of six patients including a congenital giant, concordant monozygotic twins and a child who achieved adult gigantic size","author":"Hook","year":"1967","journal-title":"J Pediatr"},{"key":"key-10.4103\/0972-2327.42941-4","first-page":"436","volume-title":"Spectrum of NSD1 mutations in Sotos and Weaver syndromes","author":"Rio","year":"2003","journal-title":"J Med Genet"},{"key":"key-10.4103\/0972-2327.42941-5","first-page":"20","volume-title":"Sotos syndrome: A study of the diagnostic criteria and natural history","author":"Cole","year":"1994","journal-title":"J Mol Genet"},{"key":"key-10.4103\/0972-2327.42941-6","first-page":"851","volume-title":"Unilateral glaucoma in sotos syndrome (cerebral gigantism","author":"Yen","year":"2000","journal-title":"Am J Ophthalmol"},{"key":"key-10.4103\/0972-2327.42941-7","doi-asserted-by":"crossref","unstructured":"Inoue K, Kato S, Numaga J, Sakurai M, Ohara C, Ouchi M, et al. Optic disk pallor and retinal atrophy in Sotos syndrome (cerebral gigantism) Am J Ophthalmol 2000;6:853-4.","DOI":"10.1016\/S0002-9394(00)00711-X"},{"key":"key-10.4103\/0972-2327.42941-8","first-page":"113","volume-title":"Gastric carcinoma in Sotos syndrome (cerebral gigantism)","author":"Le","year":"1999","journal-title":"Ann Genet"},{"key":"key-10.4103\/0972-2327.42941-9","first-page":"497","volume-title":"Sotos syndrome with septo-optic dysplasia","author":"Buyukgebiz","year":"1996","journal-title":"J Pediatr Endocrinol Metab"},{"key":"key-10.4103\/0972-2327.42941-10","first-page":"59","volume-title":"Sotos syndrome presenting with epilepsy","author":"Buyukgebiz","year":"1990","journal-title":"Turk J Pediatr"},{"key":"key-10.4103\/0972-2327.42941-11","first-page":"453","volume-title":"Congenital cardiopathy in a patient with Sotos syndrome: Description of a case","author":"Di","year":"1989","journal-title":"G Ital Cardiol"},{"key":"key-10.4103\/0972-2327.42941-12","first-page":"287","volume-title":"Diagnosing Sotos syndrome in the setting of global developmental delay and macrocephaly","author":"Srour","year":"2006","journal-title":"J Child Neurol"},{"key":"key-10.4103\/0972-2327.42941-13","first-page":"132","volume-title":"NSD1 mutations are the major cause of Sotos syndrome and occur in some cases of Weaver syndrome but are rare in other overgrowth phenotypes","author":"Douglas","year":"2003","journal-title":"Am J Hum Genet"},{"key":"key-10.4103\/0972-2327.42941-14","first-page":"56","volume-title":"Partial NSD1 deletions cause 5% of Sotos syndrome and are readily identifiable by multiplex ligation dependent probe amplification","author":"Douglas","year":"2005","journal-title":"J Med Genet"},{"key":"key-10.4103\/0972-2327.42941-15","first-page":"15","volume-title":"Analysis of the NSD 1 promoter region in patients with Sotos syndrome phenotype","author":"Visser","year":"2006","journal-title":"J Hum Genet"},{"key":"key-10.4103\/0972-2327.42941-16","first-page":"462","volume-title":"The neuroimaging findings in Sotos syndrome","author":"Schaefer","year":"1997","journal-title":"Am J Med Genet"},{"key":"key-10.4103\/0972-2327.42941-17","first-page":"614","volume-title":"Neuroradiologic findings in Sotos syndrome","author":"Horikoshi","year":"2006","journal-title":"J Child Neurol"},{"key":"key-10.4103\/0972-2327.42941-18","first-page":"197","volume-title":"Sotos syndrome(cerebral gigantism): A clinical and radiological study of 14 cases from Saudi Arabia","author":"al","year":"1999","journal-title":"Ann Trop Paediatr"},{"key":"key-10.4103\/0972-2327.42941-19","first-page":"673","volume-title":"Cerebral gigantism with West syndrome","author":"Ray","year":"2003","journal-title":"Indian Pediatr"}],"container-title":["Annals of Indian Academy of Neurology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T14:42:05Z","timestamp":1786632125000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0972-2327.42941"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008]]}},"alternative-id":["42941"],"URL":"https:\/\/doi.org\/10.4103\/0972-2327.42941","relation":{},"ISSN":["0972-2327"],"issn-type":[{"value":"0972-2327","type":"print"}],"subject":[],"published":{"date-parts":[[2008]]}}}