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Tamura A, Ohashi N, Urakami H, Miyamura S. Classification of Rickettsia tsutsugamushi in a new genus, Orientia gen. nov. as Orientia tsutsugamushi comb. nov. Int J Syst Bacteriol 1995;45:589-91.","DOI":"10.1099\/00207713-45-3-589"},{"key":"ref=2","unstructured":"2. Chogle AR. Diagnosis and treatment of scrub typhus - The Indian scenario. J Assoc Physicians India 2010;58:11-2."},{"key":"ref=3","doi-asserted-by":"crossref","unstructured":"3. Watt G, Parola P. Scrub typhus and tropical rickettsioses. Curr Opin Infect Dis 2003;16:429-36.","DOI":"10.1097\/00001432-200310000-00009"},{"key":"ref=4","unstructured":"4. Kothari VM, Karnad DR, Bichile LS. Tropical infections in the ICU. J Assoc Physicians India 2006;54:291-8."},{"key":"ref=5","unstructured":"5. Mahajan SK. Scrub typhus. J Assoc Physicians India 2005;53:954-8."},{"key":"ref=6","doi-asserted-by":"crossref","unstructured":"6. Wang CC, Liu SF, Liu JW, Chung YH, Su MC, Lin MC. Acute respiratory distress syndrome in scrub typhus. 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Varghese GM, Abraham OC, Mathai D, Thomas K, Aaron R, Kavitha ML, et al. Scrub typhus among hospitalised patients with febrile illness in South India: Magnitude and clinical predictors. J Infect 2006;52:56-60.","DOI":"10.1016\/j.jinf.2005.02.001"},{"key":"ref=14","unstructured":"14. Vivekanandan M, Mani A, Priya YS, Singh AP, Jayakumar S, Purty S. Outbreak of scrub typhus in Pondicherry. J Assoc Physicians India 2010;58:24-8."},{"key":"ref=15","doi-asserted-by":"crossref","unstructured":"15. Sharma A, Mahajan S, Gupta ML, Kanga A, Sharma V. Investigation of an outbreak of scrub typhus in the himalayan region of India. Jpn J Infect Dis 2005;58:208-10.","DOI":"10.7883\/yoken.JJID.2005.208"},{"key":"ref=16","doi-asserted-by":"crossref","unstructured":"16. Koh GC, Maude RJ, Paris DH, Newton PN, Blacksell SD. Diagnosis of scrub typhus. Am J Trop Med Hyg 2010;82:368-70.","DOI":"10.4269\/ajtmh.2010.09-0233"},{"key":"ref=17","doi-asserted-by":"crossref","unstructured":"17. Mathai E, Lloyd G, Cherian T, Abraham OC, Cherian AM. Serological evidence for the continued presence of human rickettsioses in southern India. Ann Trop Med Parasitol 2001;95:395-8.","DOI":"10.1080\/00034983.2001.11813652"},{"key":"ref=18","unstructured":"18. Kamarasu K, Malathi M, Rajagopal V, Subramani K, Jagadeeshramasamy D, Mathai E. Serological evidence for wide distribution of spotted fevers and typhus fever in Tamil Nadu. Indian J Med Res 2007;126:128-30."},{"key":"ref=19","doi-asserted-by":"crossref","unstructured":"19. Mahajan SK, Rolain JM, Sankhyan N, Kaushal RK, Raoult D. Pediatric scrub typhus in Indian Himalayas. Indian J Pediatr 2008;75:947-9.","DOI":"10.1007\/s12098-008-0198-z"},{"key":"ref=20","unstructured":"20. Mahajan SK, Kaushik M, Raina R. Relevance of Weil-Felix test in diagnosis of scrub typhus in India. J Asssoc Physicians India 2006;54:619-21."},{"key":"ref=21","doi-asserted-by":"crossref","unstructured":"21. Blacksell SD, Jenjaroen K, Phetsouvanh R, Tanganuchitcharnchai A, Phouminh P, Phongmany S, et al. Accuracy of rapid IgM-based immunochromatographic and immunoblot assays for diagnosis of acute scrub typhus and murine typhus infections in Laos. Am J Trop Med Hyg 2010;83:365-9.","DOI":"10.4269\/ajtmh.2010.09-0534"},{"key":"ref=22","doi-asserted-by":"crossref","unstructured":"22. Sonthayanon P, Chierakul W, Wuthiekanun V, Phimda K, Pukrittayakamee S, Day NP, et al. Association of high Orientia tsutsugamushi DNA loads with disease of greater severity in adults with scrub typhus. J Clin Microbiol 2009;47:430-4.","DOI":"10.1128\/JCM.01927-08"},{"key":"ref=23","doi-asserted-by":"crossref","unstructured":"23. Kim DM, Kang DW, Kim JO, Chung JH, Kim HL, Park CY, et al. Acute renal failure due to acute tubular necrosis caused by direct invasion of Orientia tsutsugamushi. 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