{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:25:45Z","timestamp":1787772345946,"version":"build-2784847793"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Crimean-Congo hemorrhagic fever is a tick-borne disease with high fatality rate that is endemic in some parts of Asia, Africa and Europe. Rapid diagnostics of Crimean-Congo hemorrhagic fever (CCHF) is necessary for appropriate clinical management of this disease and also can be useful in preventing of secondary spread from human-to-human, though, common tests which are used to diagnose Crimean-Congo hemorrhagic fever have some limitations. Here we review 1) common diagnostic tests for CCHF, 2) limitations in laboratories methods of CCHF and 3) biosensor researches for detection of CCHF. It is necessary to design and develop an effective, rapid, and also low-cost tool such as biosensor to detect Crimean-Congo hemorrhagic fever. Based on the key role of rapid detection of CCHF in the control of infection, development of a biosensor as a rapid tool seems very major in the diagnosis of CCHF, though, there are limited studies on this field and more researches are needed in this issue.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/0972-9062.328976","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T15:21:34Z","timestamp":1716909694000},"page":"383-385","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Biosensor-based methods for Crimean-Congo hemorrhagic fever virus detection"],"prefix":"10.4103","volume":"58","author":[{"given":"Milad","family":"Zandi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azadeh","family":"Rasooli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saber","family":"Soltani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samane","family":"Teymouri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shima","family":"Mohammadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samaneh","family":"Abbasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-14-20240830","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1007\/s00705-019-04253-6","article-title":"Taxonomy of the order Bunyavirales: update 2019","volume":"164","author":"Abudurexiti","year":"2019","journal-title":"Archives of virology"},{"key":"R2-14-20240830","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.3390\/v13071195","article-title":"Crimean-Congo Hemorrhagic Fever Virus: Current Advances and Future Prospects of Antiviral Strategies","volume":"13","author":"Dai","year":"2021","journal-title":"Viruses"},{"key":"R3-14-20240830","doi-asserted-by":"crossref","first-page":"162","DOI":"10.4103\/0972-9062.184851","article-title":"Examination of the specific clinical symptoms and laboratory findings of Crimean-Congo hemorrhagic fever","volume":"53","author":"Kilinc","year":"2016","journal-title":"Journal of vector borne diseases"},{"key":"R4-14-20240830","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1080\/14737159.2019.1615450","article-title":"Diagnostic approaches for crimean-congo hemorrhagic fever virus","volume":"19","author":"Papa","year":"2019","journal-title":"Expert review of molecular diagnostics"},{"key":"R5-14-20240830","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.ijid.2006.06.005","article-title":"Zoonotic infections among veterinarians in Turkey: Crimean-Congo hemorrhagic fever and beyond","volume":"10","author":"Erg\u00f6n\u00fcl","year":"2006","journal-title":"International journal of infectious diseases"},{"key":"R6-14-20240830","first-page":"57","article-title":"Evaluation of PCR and ELISA-IgM results in the laboratory diagnosis of Crimean-Congo haemorrhagic fever cases in 2008 in Turkey","volume":"44","author":"Uyar","year":"2010","journal-title":"Mikrobiyoloji bulteni"},{"key":"R7-14-20240830","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.antiviral.2004.08.001","article-title":"Crimean\u2013Congo hemorrhagic fever","volume":"64","author":"Whitehouse","year":"2004","journal-title":"Antiviral research"},{"key":"R8-14-20240830","first-page":"12","article-title":"Characteristics of headache and its relationship with disease severity in patients with Crimean\u2013Congo hemorrhagic fever","volume":"30","author":"Aksoy","year":"2018","journal-title":"Agri"},{"key":"R9-14-20240830","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1586\/14787210.2013.827890","article-title":"Epidemiological and behavioral factors associated with Crimean-Congo hemorrhagic fever virus infections in humans","volume":"11","author":"Sargianou","year":"2013","journal-title":"Expert review of anti-infective therapy"},{"key":"R10-14-20240830","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.jcv.2010.04.001","article-title":"Crimean\u2013Congo hemorrhagic fever in children","volume":"48","author":"Tezer","year":"2010","journal-title":"Journal of Clinical Virology"},{"key":"R11-14-20240830","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1002\/bab.2033","article-title":"Future developments in biosensors for field-ready SARS-CoV-2 virus diagnostics","volume":"68","author":"Fani","year":"2021","journal-title":"Biotechnology and applied biochemistry"},{"key":"R12-14-20240830","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3390\/ma12010121","article-title":"Immobilized enzymes in biosensor applications","volume":"12","author":"Nguyen","year":"2019","journal-title":"Materials"},{"key":"R14-14-20240830","doi-asserted-by":"crossref","first-page":"143","DOI":"10.4103\/1995-7645.280221","article-title":"Crimean-Congo hemorrhagic fever: etiology, diagnosis, management and potential alternative therapy","volume":"13","author":"Saleem","year":"2020","journal-title":"Asian Pacific Journal of Tropical Medicine"},{"key":"R15-14-20240830","doi-asserted-by":"crossref","first-page":"174","DOI":"10.4103\/0972-9062.263720","article-title":"Seroepidemiological survey of Crimean-Congo haemorrhagic fever among high-risk groups in the west of Iran","volume":"56","author":"Shahbazi","year":"2019","journal-title":"Journal of vector borne diseases"},{"key":"R16-14-20240830","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.coviro.2012.03.001","article-title":"Crimean\u2013Congo hemorrhagic fever virus: new outbreaks, new discoveries","volume":"2","author":"Ergonul","year":"2012","journal-title":"Current opinion in virology"},{"key":"R17-14-20240830","doi-asserted-by":"crossref","first-page":"387.e1","DOI":"10.1016\/j.cmi.2015.11.024","article-title":"Healthcare-associated Crimean-Congo haem- orrhagic fever in Turkey, 2002\u20132014: a multicentre retrospective cross-sectional study","volume":"22","author":"Leblebicioglu","year":"2016","journal-title":"Clinical Microbiology and Infection"},{"key":"R18-14-20240830","doi-asserted-by":"crossref","first-page":"e0007100","DOI":"10.1371\/journal.pntd.0007100","article-title":"Clinical and molecular epidemiology of Crimean- Congo hemorrhagic fever in Oman","volume":"13","author":"Al-Abri","year":"2019","journal-title":"PLoS neglected tropical diseases"},{"key":"R19-14-20240830","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.trac.2015.03.006","article-title":"Recent developments in recognition elements for chemical sensors and biosensors","volume":"68","author":"Justino","year":"2015","journal-title":"TrAC Trends in Analytical Chemistry"},{"key":"R21-14-20240830","doi-asserted-by":"crossref","first-page":"8394","DOI":"10.1021\/acs.analchem.5b01728","article-title":"Fiber-optic immunosensor for detection of Crimean- Congo hemorrhagic fever IgG antibodies in patients","volume":"87","author":"Algaar","year":"2015","journal-title":"Analytical chemistry"},{"key":"R22-14-20240830","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-021-91826-8","article-title":"Aptamer based diagnosis of crimean-congo hemorrhagic fever from clinical specimens","volume":"11","author":"Jalali","year":"2021","journal-title":"Scientific Reports"},{"key":"R23-14-20240830","doi-asserted-by":"crossref","first-page":"5613","DOI":"10.1039\/D0AY01137A","article-title":"A lateral flow biosensor based on gold nanoparticles detects four hemorrhagic fever viruses","volume":"12","author":"Zhao","year":"2020","journal-title":"Analytical Methods"}],"container-title":["Journal of Vector Borne Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/0972-9062.328976","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:40:17Z","timestamp":1787769617000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/0972-9062.328976"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/0972-9062.328976","relation":{},"ISSN":["0972-9062"],"issn-type":[{"value":"0972-9062","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]}}}